Project measure / variable:   Schoonjans1   TCDCA_plasma_t60_HFD

ID, description, units MPD:112743   TCDCA_plasma_t60_HFD   plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means49.007   ng/mL
Median of the strain means44.797   ng/mL
SD of the strain means± 26.38
Coefficient of variation (CV)0.5383
Min–max range of strain means9.0965   –   113.8   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 100427.3767 2869.3536 2.5393 < 0.0001
Residuals 121 136729.9748 1129.9998


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 14.317 5.6298   5 2.5177 0.3932 10.284, 24.25 -1.32
BXD100 m 24.721 14.987   9 4.9956 0.6062 2.95, 53.87 -0.92
BXD11 m 30.919 10.25   3 5.9177 0.3315 20.224, 40.656 -0.69
BXD12 m 44.395 43.377   4 21.689 0.9771 8.416, 107.5 -0.17
BXD27 m 95.33 35.92   5 16.064 0.3768 57.35, 142.2 1.76
BXD32 m 28.275 9.2854   4 4.6427 0.3284 19.358, 40.666 -0.79
BXD34 m 55.41 22.924   4 11.462 0.4138 31.774, 86.62 0.24
BXD39 m 49.838 35.601   3 20.554 0.7143 24.722, 90.58 0.03
BXD40 m 66.57 24.136   4 12.068 0.3626 40.796, 91.96 0.67
BXD43 m 19.272 6.0777   5 2.718 0.3154 11.008, 27.096 -1.13
BXD45 m 57.7 25.631   5 11.462 0.4442 23.7, 86.84 0.33
BXD48 m 72.6 47.254   5 21.133 0.6509 22.482, 134.6 0.89
BXD48a m 100.9 63.52   4 31.762 0.6295 48.06, 176.0 1.97
BXD49 m 49.784 24.582   5 10.993 0.4938 31.494, 92.97 0.03
BXD51 m 45.199 19.263   3 11.121 0.4262 33.842, 67.44 -0.14
BXD53 m 54.59 40.286   5 18.016 0.738 17.846, 110.8 0.21
BXD55 m 33.828 10.97   5 4.906 0.3243 17.586, 48.202 -0.58
BXD6 m 27.147 26.476   5 11.84 0.9753 6.648, 69.82 -0.83
BXD62 m 63.58 20.697   4 10.348 0.3255 33.32, 78.46 0.55
BXD63 m 19.645 6.8879   5 3.0804 0.3506 11.894, 29.016 -1.11
BXD64 m 43.309 34.219   5 15.303 0.7901 18.824, 102.9 -0.22
BXD66 m 30.251 16.706   3 9.6453 0.5522 18.99, 49.446 -0.71
BXD67 m 9.0965 2.9544   5 1.3212 0.3248 6.628, 13.916 -1.51
BXD69 m 113.8 83.89   4 41.945 0.7374 29.0, 221.9 2.46
BXD73 m 52.55 22.366   3 12.913 0.4256 31.754, 76.21 0.13
BXD75 m 72.89 56.06   4 28.032 0.7691 36.496, 155.2 0.91
BXD77 m 64.15 49.948   5 22.337 0.7786 28.668, 147.4 0.57
BXD79 m 65.08 54.03   5 24.165 0.8303 17.722, 123.6 0.61
BXD8 m 34.364 17.542   3 10.128 0.5105 21.938, 54.43 -0.56
BXD81 m 61.48 39.968   5 17.874 0.6501 12.7, 121.0 0.47
BXD84 m 23.3 24.762   5 11.074 1.0627 3.136, 66.2 -0.97
BXD87 m 32.004 11.93   4 5.9648 0.3728 17.892, 42.008 -0.64
BXD89 m 42.287 12.569   5 5.6211 0.2972 24.514, 58.29 -0.25
BXD90 m 40.161 19.471   4 9.7355 0.4848 16.179, 62.97 -0.34
C57BL/6J m 108.5 94.46   2   66.8 0.8706 41.708, 175.3 2.26
DBA/2J m 17.027 14.028   3 8.0993 0.8239 7.922, 33.182 -1.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 14.3172 15.033294993 44.0795726582 -15.4451726582
BXD100 m 24.7211111111 11.20515651 46.9046739229 2.5375482993
BXD11 m 30.9193333333 19.4079003822 69.3423912162 -7.5037245496
BXD12 m 44.3955 16.8077347651 77.6708442177 11.1201557823
BXD27 m 95.328 15.033294993 125.0903726582 65.5656273418
BXD32 m 28.2755 16.8077347651 61.5508442177 -4.9998442177
BXD34 m 55.405 16.8077347651 88.6803442177 22.1296557823
BXD39 m 49.838 19.4079003822 88.2610578829 11.4149421171
BXD40 m 66.574 16.8077347651 99.8493442177 33.2986557823
BXD43 m 19.2724 15.033294993 49.0347726582 -10.4899726582
BXD45 m 57.7012 15.033294993 87.4635726582 27.9388273418
BXD48 m 72.5976 15.033294993 102.3599726582 42.8352273418
BXD48a m 100.9155 16.8077347651 134.1908442177 67.6401557823
BXD49 m 49.784 15.033294993 79.5463726582 20.0216273418
BXD51 m 45.199 19.4079003822 83.6220578829 6.7759421171
BXD53 m 54.5912 15.033294993 84.3535726582 24.8288273418
BXD55 m 33.8284 15.033294993 63.5907726582 4.0660273418
BXD6 m 27.147 15.033294993 56.9093726582 -2.6153726582
BXD62 m 63.5825 16.8077347651 96.8578442177 30.3071557823
BXD63 m 19.6446 15.033294993 49.4069726582 -10.1177726582
BXD64 m 43.3092 15.033294993 73.0715726582 13.5468273418
BXD66 m 30.2513333333 19.4079003822 68.6743912162 -8.1717245496
BXD67 m 9.09652 15.033294993 38.8588926582 -20.6658526582
BXD69 m 113.7675 16.8077347651 147.0428442177 80.4921557823
BXD73 m 52.5493333333 19.4079003822 90.9723912162 14.1262754504
BXD75 m 72.8945 16.8077347651 106.1698442177 39.6191557823
BXD77 m 64.15 15.033294993 93.9123726582 34.3876273418
BXD79 m 65.0768 15.033294993 94.8391726582 35.3144273418
BXD8 m 34.364 19.4079003822 72.7870578829 -4.0590578829
BXD81 m 61.4836 15.033294993 91.2459726582 31.7212273418
BXD84 m 23.3 15.033294993 53.0623726582 -6.4623726582
BXD87 m 32.0035 16.8077347651 65.2788442177 -1.2718442177
BXD89 m 42.2872 15.033294993 72.0495726582 12.5248273418
BXD90 m 40.16075 16.8077347651 73.4360942177 6.8854057823
C57BL/6J m 108.504 23.7697264575 155.5624430853 61.4455569147
DBA/2J m 17.0268333333 19.4079003822 55.4498912162 -21.3962245496




  GWAS USING LINEAR MIXED MODELS