Project measure / variable:   Schoonjans1   TCDCA_plasma_t60_CD

ID, description, units MPD:112742   TCDCA_plasma_t60_CD   plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means26.96   ng/mL
Median of the strain means28.66   ng/mL
SD of the strain means± 12.467
Coefficient of variation (CV)0.4624
Min–max range of strain means6.9875   –   58.42   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 25215.8438 720.4527 2.1721 0.0009
Residuals 130 43119.4642 331.6882


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 9.8684 4.623   5 2.0675 0.4685 4.47, 15.632 -1.37
BXD100 m 34.829 9.8341   5 4.3979 0.2824 24.14, 49.116 0.63
BXD11 m 33.544 23.361   4 11.68 0.6964 13.514, 66.77 0.53
BXD12 m 32.996 13.356   3 7.711 0.4048 18.682, 45.124 0.48
BXD27 m 33.265 27.913   4 13.957 0.8391 16.206, 74.87 0.51
BXD32 m 19.27 14.687   5 6.5682 0.7622 2.344, 40.106 -0.62
BXD34 m 21.726 9.3545   5 4.1835 0.4306 15.826, 38.192 -0.42
BXD39 m 13.036 6.9356   3 4.0043 0.532 5.028, 17.118 -1.12
BXD40 m 28.937 12.275   4 6.1373 0.4242 14.856, 42.306 0.16
BXD43 m 9.306 8.4234   7 3.1837 0.9052 2.87, 27.292 -1.42
BXD45 m 28.705 4.724   4 2.362 0.1646 23.48, 34.936 0.14
BXD48 m 29.107 23.695   5 10.597 0.8141 13.894, 70.88 0.17
BXD48a m 52.41 50.26   4 25.132 0.9591 8.044, 111.9 2.04
BXD49 m 28.916 13.904   5 6.218 0.4808 13.96, 50.51 0.16
BXD51 m 22.542 8.1279   5 3.6349 0.3606 12.598, 35.23 -0.35
BXD53 m 29.542 15.756   4 7.8778 0.5333 8.948, 45.226 0.21
BXD55 m 14.534 9.4116   5 4.209 0.6476 6.414, 29.928 -1.0
BXD6 m 33.431 30.936   5 13.835 0.9254 6.81, 80.61 0.52
BXD62 m 34.654 11.878   5 5.3122 0.3428 25.644, 54.79 0.62
BXD63 m 11.646 8.5318   4 4.2659 0.7326 3.98, 19.576 -1.23
BXD64 m 38.41 9.9468   5 4.4484 0.259 28.414, 54.21 0.92
BXD66 m 28.614 10.767   5 4.8152 0.3763 16.684, 43.048 0.13
BXD67 m 6.9875 7.1303   4 3.5651 1.0204 2.164, 17.516 -1.6
BXD69 m 37.288 13.198   5 5.9025 0.354 23.368, 56.29 0.83
BXD73 m 23.145 25.481   4 12.74 1.1009 2.856, 60.05 -0.31
BXD75 m 41.171 35.12   5 15.706 0.853 20.138, 102.9 1.14
BXD77 m 24.03 12.449   5 5.5672 0.5181 9.032, 39.686 -0.24
BXD79 m 33.192 9.9819   5 4.4641 0.3007 21.802, 43.356 0.5
BXD8 m 58.42 20.081   5 8.9805 0.3437 31.834, 86.84 2.52
BXD81 m 9.9867 5.9827   3 3.4541 0.5991 6.362, 16.892 -1.36
BXD84 m 25.932 10.418   5 4.6589 0.4017 12.804, 41.428 -0.08
BXD87 m 14.721 4.9141   5 2.1976 0.3338 9.11, 21.082 -0.98
BXD89 m 49.928 39.602   5 17.711 0.7932 17.298, 115.4 1.84
BXD90 m 14.416 9.2195   5 4.1231 0.6395 6.886, 26.508 -1.01
C57BL/6J m 28.378 12.358   5 5.5267 0.4355 14.902, 41.666 0.11
DBA/2J m 13.676 12.124   4 6.062 0.8866 4.264, 31.482 -1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 9.8684 8.1447920326 25.9818969637 -6.2450969637
BXD100 m 34.8292 8.1447920326 50.9426969637 18.7157030363
BXD11 m 33.5435 9.1061543237 51.5589372831 15.5280627169
BXD12 m 32.996 10.5148813002 53.7984351299 12.1935648701
BXD27 m 33.26475 9.1061543237 51.2801872831 15.2493127169
BXD32 m 19.2696 8.1447920326 35.3830969637 3.1561030363
BXD34 m 21.726 8.1447920326 37.8394969637 5.6125030363
BXD39 m 13.036 10.5148813002 33.8384351299 -7.7664351299
BXD40 m 28.937 9.1061543237 46.9524372831 10.9215627169
BXD43 m 9.306 6.8836056402 22.9243905174 -4.3123905174
BXD45 m 28.7045 9.1061543237 46.7199372831 10.6890627169
BXD48 m 29.1068 8.1447920326 45.2202969637 12.9933030363
BXD48a m 52.4075 9.1061543237 70.4229372831 34.3920627169
BXD49 m 28.9164 8.1447920326 45.0298969637 12.8029030363
BXD51 m 22.5416 8.1447920326 38.6550969637 6.4281030363
BXD53 m 29.542 9.1061543237 47.5574372831 11.5265627169
BXD55 m 14.534 8.1447920326 30.6474969637 -1.5794969637
BXD6 m 33.4312 8.1447920326 49.5446969637 17.3177030363
BXD62 m 34.6536 8.1447920326 50.7670969637 18.5401030363
BXD63 m 11.6465 9.1061543237 29.6619372831 -6.3689372831
BXD64 m 38.4096 8.1447920326 54.5230969637 22.2961030363
BXD66 m 28.6136 8.1447920326 44.7270969637 12.5001030363
BXD67 m 6.9875 9.1061543237 25.0029372831 -11.0279372831
BXD69 m 37.288 8.1447920326 53.4014969637 21.1745030363
BXD73 m 23.1445 9.1061543237 41.1599372831 5.1290627169
BXD75 m 41.1712 8.1447920326 57.2846969637 25.0577030363
BXD77 m 24.0296 8.1447920326 40.1430969637 7.9161030363
BXD79 m 33.192 8.1447920326 49.3054969637 17.0785030363
BXD8 m 58.4208 8.1447920326 74.5342969637 42.3073030363
BXD81 m 9.9866666667 10.5148813002 30.7891017966 -10.8157684632
BXD84 m 25.932 8.1447920326 42.0454969637 9.8185030363
BXD87 m 14.7208 8.1447920326 30.8342969637 -1.3926969637
BXD89 m 49.9276 8.1447920326 66.0410969637 33.8141030363
BXD90 m 14.416 8.1447920326 30.5294969637 -1.6974969637
C57BL/6J m 28.3784 8.1447920326 44.4918969637 12.2649030363
DBA/2J m 13.6755 9.1061543237 31.6909372831 -4.3399372831




  GWAS USING LINEAR MIXED MODELS