Project measure / variable:   Schoonjans1   TCA_plasma_t60_CD

ID, description, units MPD:112740   TCA_plasma_t60_CD   plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means264.1   ng/mL
Median of the strain means262.1   ng/mL
SD of the strain means± 126.1
Coefficient of variation (CV)0.4775
Min–max range of strain means81.98   –   645.7   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 2546156.4344 72747.3267 1.5469 0.0417
Residuals 130 6113718.0697 47028.6005


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 248.3 88.74   5 39.684 0.3574 112.5, 336.5 -0.12
BXD100 m 287.0 58.01   5 25.944 0.2021 191.7, 332.5 0.18
BXD11 m 305.3 191.6   4 95.81 0.6276 70.22, 491.1 0.33
BXD12 m 133.1 27.84   3 16.074 0.2092 111.1, 164.4 -1.04
BXD27 m 239.8 179.1   4 89.55 0.7471 139.6, 508.1 -0.19
BXD32 m 330.1 277.9   5 124.3 0.8417 73.37, 750.0 0.52
BXD34 m 169.3 38.105   5 17.041 0.225 120.7, 223.0 -0.75
BXD39 m 323.0 138.0   3 79.7 0.4273 197.9, 471.1 0.47
BXD40 m 277.2 108.9   4 54.47 0.3929 166.3, 423.2 0.1
BXD43 m 122.4 131.1   7 49.54 1.0708 27.408, 386.9 -1.12
BXD45 m 206.3 55.7   4 27.849 0.2699 144.7, 277.9 -0.46
BXD48 m 269.3 224.3   5 100.3 0.8328 136.0, 667.8 0.04
BXD48a m 290.0 302.0   4 151.0 1.0412 29.046, 654.3 0.21
BXD49 m 233.8 116.9   5 52.29 0.5001 91.27, 404.7 -0.24
BXD51 m 330.9 130.4   5 58.3 0.3939 171.1, 480.7 0.53
BXD53 m 549.4 540.7   4 270.3 0.9842 48.664, 1297.0 2.26
BXD55 m 111.9 67.29   5 30.095 0.6012 43.058, 217.1 -1.21
BXD6 m 645.7 743.9   5 332.7 1.1522 73.07, 1856.0 3.03
BXD62 m 286.8 166.0   5 74.24 0.5788 163.0, 559.1 0.18
BXD63 m 156.3 123.2   4 61.58 0.7878 37.392, 293.2 -0.85
BXD64 m 226.8 74.86   5 33.478 0.3301 144.3, 336.3 -0.3
BXD66 m 276.1 132.1   5 59.05 0.4782 137.9, 453.7 0.1
BXD67 m 131.8 80.91   4 40.457 0.614 49.328, 243.1 -1.05
BXD69 m 336.1 111.7   5 49.965 0.3324 198.7, 472.7 0.57
BXD73 m 411.8 389.2   4 194.6 0.9452 117.9, 971.7 1.17
BXD75 m 315.5 299.0   5 133.7 0.9476 85.14, 776.6 0.41
BXD77 m 130.1 59.18   5 26.465 0.4547 54.9, 194.5 -1.06
BXD79 m 464.0 206.6   5 92.38 0.4451 116.3, 658.5 1.59
BXD8 m 384.4 89.53   5 40.04 0.2329 285.4, 519.4 0.95
BXD81 m 81.98 57.36   3 33.117 0.6997 37.774, 146.8 -1.44
BXD84 m 249.8 91.15   5 40.762 0.3649 138.6, 366.1 -0.11
BXD87 m 255.0 95.2   5 42.577 0.3734 149.4, 373.9 -0.07
BXD89 m 186.2 174.5   5 78.05 0.9374 45.202, 485.2 -0.62
BXD90 m 91.45 65.75   5 29.405 0.719 37.278, 183.7 -1.37
C57BL/6J m 354.4 140.1   5 62.63 0.3952 170.4, 488.6 0.72
DBA/2J m 94.51 68.64   4 34.321 0.7263 20.684, 182.3 -1.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 248.28 96.9830918625 440.1494486005 56.4105513995
BXD100 m 287.02 96.9830918625 478.8894486005 95.1505513995
BXD11 m 305.305 108.4303930363 519.821564938 90.788435062
BXD12 m 133.1 125.2046332157 380.8023930252 -114.6023930252
BXD27 m 239.75 108.4303930363 454.266564938 25.233435062
BXD32 m 330.12 96.9830918625 521.9894486005 138.2505513995
BXD34 m 169.34 96.9830918625 361.2094486005 -22.5294486005
BXD39 m 323.0333333333 125.2046332157 570.7357263585 75.3309403081
BXD40 m 277.25 108.4303930363 491.766564938 62.733435062
BXD43 m 122.402 81.9656727243 284.5612808371 -39.7572808371
BXD45 m 206.35 108.4303930363 420.866564938 -8.166564938
BXD48 m 269.28 96.9830918625 461.1494486005 77.4105513995
BXD48a m 290.004 108.4303930363 504.520564938 75.487435062
BXD49 m 233.834 96.9830918625 425.7034486005 41.9645513995
BXD51 m 330.92 96.9830918625 522.7894486005 139.0505513995
BXD53 m 549.366 108.4303930363 763.882564938 334.849435062
BXD55 m 111.9296 96.9830918625 303.7990486005 -79.9398486005
BXD6 m 645.654 96.9830918625 837.5234486005 453.7845513995
BXD62 m 286.84 96.9830918625 478.7094486005 94.9705513995
BXD63 m 156.3255 108.4303930363 370.842064938 -58.191064938
BXD64 m 226.8 96.9830918625 418.6694486005 34.9305513995
BXD66 m 276.14 96.9830918625 468.0094486005 84.2705513995
BXD67 m 131.782 108.4303930363 346.298564938 -82.734564938
BXD69 m 336.14 96.9830918625 528.0094486005 144.2705513995
BXD73 m 411.8 108.4303930363 626.316564938 197.283435062
BXD75 m 315.508 96.9830918625 507.3774486005 123.6385513995
BXD77 m 130.134 96.9830918625 322.0034486005 -61.7354486005
BXD79 m 464.04 96.9830918625 655.9094486005 272.1705513995
BXD8 m 384.36 96.9830918625 576.2294486005 192.4905513995
BXD81 m 81.9813333333 125.2046332157 329.6837263585 -165.7210596919
BXD84 m 249.8 96.9830918625 441.6694486005 57.9305513995
BXD87 m 254.98 96.9830918625 446.8494486005 63.1105513995
BXD89 m 186.1864 96.9830918625 378.0558486005 -5.6830486005
BXD90 m 91.4464 96.9830918625 283.3158486005 -100.4230486005
C57BL/6J m 354.38 96.9830918625 546.2494486005 162.5105513995
DBA/2J m 94.5085 108.4303930363 309.025064938 -120.008064938




  GWAS USING LINEAR MIXED MODELS