Project measure / variable:   Schoonjans1   TbMCA_plasma_t60_CD

ID, description, units MPD:112738   TbMCA_plasma_t60_CD   plasma bile acid tauro-β-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-β-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means151.2   ng/mL
Median of the strain means114.7   ng/mL
SD of the strain means± 101.8
Coefficient of variation (CV)0.6736
Min–max range of strain means27.072   –   404.0   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1660051.0205 47430.0292 2.3062 0.0004
Residuals 129 2653022.2057 20566.0636


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 51.94 23.328   5 10.433 0.4491 16.41, 70.79 -0.97
BXD100 m 144.6 19.355   5 8.6558 0.1338 125.8, 177.3 -0.06
BXD11 m 175.6 118.3   4 59.13 0.6733 27.396, 280.9 0.24
BXD12 m 101.0 19.991   3 11.542 0.1979 80.0, 119.8 -0.49
BXD27 m 315.8 183.6   4 91.8 0.5815 195.5, 589.0 1.62
BXD32 m 112.4 73.8   5 33.005 0.6569 19.932, 196.1 -0.38
BXD34 m 60.26 17.448   5 7.803 0.2896 38.496, 81.38 -0.89
BXD39 m 192.5 122.2   3 70.55 0.6349 110.3, 332.9 0.41
BXD40 m 117.0 43.66   4 21.83 0.3733 77.5, 157.6 -0.34
BXD43 m 78.02 78.13   7 29.532 1.0015 17.472, 239.9 -0.72
BXD45 m 182.4 26.532   4 13.266 0.1455 145.1, 203.0 0.31
BXD48 m 80.68 58.2   5 26.027 0.7214 42.33, 182.1 -0.69
BXD48a m 110.6 113.5   4 56.73 1.026 10.146, 260.0 -0.4
BXD49 m 102.7 30.21   5 13.51 0.2943 69.63, 140.0 -0.48
BXD51 m 248.6 137.0   5 61.27 0.551 102.0, 387.3 0.96
BXD53 m 404.0 525.4   4 262.7 1.3004 21.062, 1174.0 2.48
BXD55 m 48.853 20.021   5 8.9538 0.4098 34.704, 80.1 -1.0
BXD6 m 396.9 472.3   5 211.2 1.1901 26.004, 1113.0 2.41
BXD62 m 297.6 150.3   5 67.2 0.5049 194.3, 560.7 1.44
BXD63 m 43.769 26.1   4 13.05 0.5963 17.68, 75.76 -1.05
BXD64 m 167.2 87.55   5 39.152 0.5237 63.45, 276.5 0.16
BXD66 m 201.1 111.0   5 49.638 0.552 95.53, 368.6 0.49
BXD67 m 105.0 93.95   4 46.973 0.8951 19.048, 234.6 -0.45
BXD69 m 85.17 30.56   5 13.667 0.3588 48.906, 125.3 -0.65
BXD73 m 174.6 194.9   4 97.46 1.1167 50.52, 463.5 0.23
BXD75 m 152.5 149.9   5 67.02 0.9826 37.648, 391.4 0.01
BXD77 m 65.52 40.091   5 17.929 0.6119 20.724, 116.3 -0.84
BXD79 m 206.2 78.12   5 34.937 0.3788 83.79, 301.6 0.54
BXD8 m 357.1 85.19   5 38.097 0.2385 256.2, 460.8 2.02
BXD81 m 27.072 17.051   3 9.8447 0.6299 12.48, 45.816 -1.22
BXD84 m 146.5 51.53   5 23.047 0.3517 87.38, 203.7 -0.05
BXD87 m 105.8 39.598   4 19.799 0.3743 66.55, 146.0 -0.45
BXD89 m 93.13 95.24   5 42.595 1.0227 30.762, 260.7 -0.57
BXD90 m 32.387 24.347   5 10.888 0.7517 13.032, 72.39 -1.17
C57BL/6J m 226.4 91.23   5 40.8 0.403 124.3, 366.8 0.74
DBA/2J m 31.017 17.7   4 8.8502 0.5707 8.548, 46.358 -1.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 51.9448 64.1343334103 178.836149397 -74.946549397
BXD100 m 144.62 64.1343334103 271.511349397 17.728650603
BXD11 m 175.649 71.7043645985 317.5178415042 33.7801584958
BXD12 m 101.0 82.7970684061 264.8160276641 -62.8160276641
BXD27 m 315.75 71.7043645985 457.6188415042 173.8811584958
BXD32 m 112.3544 64.1343334103 239.245749397 -14.536949397
BXD34 m 60.2568 64.1343334103 187.148149397 -66.634549397
BXD39 m 192.4666666667 82.7970684061 356.2826943308 28.6506390026
BXD40 m 116.965 71.7043645985 258.8338415042 -24.9038415042
BXD43 m 78.0194285714 54.2034047559 185.2621924025 -29.2233352597
BXD45 m 182.375 71.7043645985 324.2438415042 40.5061584958
BXD48 m 80.6768 64.1343334103 207.568149397 -46.214549397
BXD48a m 110.5825 71.7043645985 252.4513415042 -31.2863415042
BXD49 m 102.668 64.1343334103 229.559349397 -24.223349397
BXD51 m 248.64 64.1343334103 375.531349397 121.748650603
BXD53 m 404.0405 71.7043645985 545.9093415042 262.1716584958
BXD55 m 48.8528 64.1343334103 175.744149397 -78.038549397
BXD6 m 396.9068 64.1343334103 523.798149397 270.015450603
BXD62 m 297.62 64.1343334103 424.511349397 170.728650603
BXD63 m 43.769 71.7043645985 185.6378415042 -98.0998415042
BXD64 m 167.17 64.1343334103 294.061349397 40.278650603
BXD66 m 201.086 64.1343334103 327.977349397 74.194650603
BXD67 m 104.9545 71.7043645985 246.8233415042 -36.9143415042
BXD69 m 85.1732 64.1343334103 212.064549397 -41.718149397
BXD73 m 174.56 71.7043645985 316.4288415042 32.6911584958
BXD75 m 152.5136 64.1343334103 279.404949397 25.622250603
BXD77 m 65.5172 64.1343334103 192.408549397 -61.374149397
BXD79 m 206.218 64.1343334103 333.109349397 79.326650603
BXD8 m 357.14 64.1343334103 484.031349397 230.248650603
BXD81 m 27.072 82.7970684061 190.8880276641 -136.7440276641
BXD84 m 146.546 64.1343334103 273.437349397 19.654650603
BXD87 m 105.7825 71.7043645985 247.6513415042 -36.0863415042
BXD89 m 93.1264 64.1343334103 220.017749397 -33.764949397
BXD90 m 32.3868 64.1343334103 159.278149397 -94.504549397
C57BL/6J m 226.38 64.1343334103 353.271349397 99.488650603
DBA/2J m 31.0165 71.7043645985 172.8853415042 -110.8523415042




  GWAS USING LINEAR MIXED MODELS