Project measure / variable:   Schoonjans1   GCA_plasma_t60_HFD

ID, description, units MPD:112733   GCA_plasma_t60_HFD   plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   33 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested33 strains
Mean of the strain means1.6811   ng/mL
Median of the strain means0.90467   ng/mL
SD of the strain means± 1.8279
Coefficient of variation (CV)1.0873
Min–max range of strain means0.05   –   7.077   ng/mL
Mean sample size per strain3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 30 360.8853 12.0295 2.2401 0.0019
Residuals 89 477.9383 5.3701


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.666 0.42909   5 0.1919 0.6443 0.22, 1.344 -0.56
BXD100 m 0.1328 0.18656   5 0.08343 1.4048 0.01, 0.46 -0.85
BXD11 m 0.20133 0.30215   3 0.17445 1.5008 0.016, 0.55 -0.81
BXD12 m 0.75667 0.51328   3 0.29635 0.6784 0.174, 1.142 -0.51
BXD27 m 0.8505 1.5745   4 0.78723 1.8512 0.014, 3.21 -0.45
BXD32 m 1.4275 0.39193   4 0.19596 0.2746 0.92, 1.872 -0.14
BXD34 m 2.5025 3.5488   4 1.7744 1.4181 0.238, 7.778 0.45
BXD39 m 0.90467 1.2397   3 0.71574 1.3703 0.122, 2.334 -0.42
BXD40 m 0.977 0.71403   4 0.35701 0.7308 0.102, 1.846 -0.39
BXD45 m 0.4528 0.23443   5 0.10484 0.5177 0.082, 0.732 -0.67
BXD48 m 0.868 1.2056   5 0.53917 1.389 0.06, 2.966 -0.44
BXD48a m 3.055 3.9078   4 1.9539 1.2791 0.158, 8.466 0.75
BXD49 m 2.6048 1.5963   5 0.71388 0.6128 0.982, 5.14 0.51
BXD51 m 0.123 0.00989949   2   0.007 0.0805 0.116, 0.13 -0.85
BXD53 m 2.592 3.5137   4 1.7569 1.3556 0.032, 7.702 0.5
BXD55 m 1.2568 0.42974   5 0.19219 0.3419 0.61, 1.684 -0.23
BXD6 m 2.8685 3.6591   4 1.8296 1.2756 0.18182, 8.258 0.65
BXD63 m 1.0616 1.1291   5 0.50496 1.0636 0.062, 2.3476 -0.34
BXD64 m 4.516 3.8655   5 1.7287 0.856 2.386, 11.398 1.55
BXD66 m 0.148 0.0   1   0.0 0.0 0.148, 0.148 -0.84
BXD67 m 0.2328 0.13465   5 0.06022 0.5784 0.07, 0.4 -0.79
BXD69 m 4.035 3.6704   4 1.8352 0.9096 0.278, 8.58 1.29
BXD73 m 3.8767 1.3163   3 0.75997 0.3395 2.722, 5.31 1.2
BXD75 m 2.1255 2.6792   4 1.3396 1.2605 0.452, 6.126 0.24
BXD77 m 2.4205 2.5457   4 1.2728 1.0517 0.082, 6.046 0.4
BXD79 m 0.29933 0.261   3 0.15069 0.8719 0.038, 0.56 -0.76
BXD8 m 0.41667 0.35113   3 0.20272 0.8427 0.124, 0.806 -0.69
BXD81 m 6.3968 4.9655   5 2.2207 0.7763 0.526, 11.416 2.58
BXD84 m 0.309 0.21637   2   0.153 0.7002 0.156, 0.462 -0.75
BXD87 m 0.05 0.02546   2   0.018 0.5091 0.032, 0.068 -0.89
BXD89 m 0.2125 0.0971   4 0.04855 0.4569 0.158, 0.358 -0.8
BXD90 m 0.06 0.0   1   0.0 0.0 0.06, 0.06 -0.89
C57BL/6J m 7.077 6.0995   2   4.313 0.8619 2.764, 11.39 2.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.666 1.036348681 2.7252027544 -1.3932027544
BXD100 m 0.1328 1.036348681 2.1920027544 -1.9264027544
BXD11 m 0.2013333333 1.3379203941 2.8597526581 -2.4570859914
BXD12 m 0.7566666667 1.3379203941 3.4150859914 -1.9017526581
BXD27 m 0.8505 1.1586730495 3.1527586691 -1.4517586691
BXD32 m 1.4275 1.1586730495 3.7297586691 -0.8747586691
BXD34 m 2.5025 1.1586730495 4.8047586691 0.2002413309
BXD39 m 0.9046666667 1.3379203941 3.5630859914 -1.7537526581
BXD40 m 0.977 1.1586730495 3.2792586691 -1.3252586691
BXD45 m 0.4528 1.036348681 2.5120027544 -1.6064027544
BXD48 m 0.868 1.036348681 2.9272027544 -1.1912027544
BXD48a m 3.055 1.1586730495 5.3572586691 0.7527413309
BXD49 m 2.6048 1.036348681 4.6640027544 0.5455972456
BXD51 m 0.123 1.638611141 3.378885434 -3.132885434
BXD53 m 2.592 1.1586730495 4.8942586691 0.2897413309
BXD55 m 1.2568 1.036348681 3.3160027544 -0.8024027544
BXD6 m 2.868455 1.1586730495 5.1707136691 0.5661963309
BXD63 m 1.061594 1.036348681 3.1207967544 -0.9976087544
BXD64 m 4.516 1.036348681 6.5752027544 2.4567972456
BXD67 m 0.2328 1.036348681 2.2920027544 -1.8264027544
BXD69 m 4.035 1.1586730495 6.3372586691 1.7327413309
BXD73 m 3.8766666667 1.3379203941 6.5350859914 1.2182473419
BXD75 m 2.1255 1.1586730495 4.4277586691 -0.1767586691
BXD77 m 2.4205 1.1586730495 4.7227586691 0.1182413309
BXD79 m 0.2993333333 1.3379203941 2.9577526581 -2.3590859914
BXD8 m 0.4166666667 1.3379203941 3.0750859914 -2.2417526581
BXD81 m 6.3968 1.036348681 8.4560027544 4.3375972456
BXD84 m 0.309 1.638611141 3.564885434 -2.946885434
BXD87 m 0.05 1.638611141 3.305885434 -3.205885434
BXD89 m 0.2125 1.1586730495 2.5147586691 -2.0897586691
C57BL/6J m 7.077 1.638611141 10.332885434 3.821114566




  GWAS USING LINEAR MIXED MODELS