Project measure / variable:   Schoonjans1   GCA_plasma_t60_CD

ID, description, units MPD:112732   GCA_plasma_t60_CD   plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means1.3705   ng/mL
Median of the strain means0.9037   ng/mL
SD of the strain means± 1.1726
Coefficient of variation (CV)0.8556
Min–max range of strain means0.066   –   4.9624   ng/mL
Mean sample size per strain4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 198.0285 5.8244 4.2215 < 0.0001
Residuals 110 151.7664 1.3797


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.9524 0.56482   5 0.2526 0.5931 0.49, 1.816 -0.36
BXD100 m 0.8132 0.46345   5 0.20726 0.5699 0.452, 1.592 -0.48
BXD11 m 0.855 0.56943   4 0.28471 0.666 0.186, 1.568 -0.44
BXD12 m 1.0173 0.21214   3 0.12248 0.2085 0.79, 1.21 -0.3
BXD27 m 0.53959 0.75635   4 0.37818 1.4017 0.07, 1.666 -0.71
BXD32 m 2.3864 1.7102   5 0.76481 0.7166 0.72, 4.794 0.87
BXD34 m 1.6932 0.73926   5 0.33061 0.4366 0.52, 2.572 0.28
BXD39 m 0.50667 0.78245   3 0.45175 1.5443 0.04, 1.41 -0.74
BXD40 m 2.8655 1.4975   4 0.74873 0.5226 0.814, 4.192 1.27
BXD43 m 0.416 0.0   1   0.0 0.0 0.416, 0.416 -0.81
BXD45 m 0.5195 0.24713   4 0.12357 0.4757 0.326, 0.876 -0.73
BXD48 m 1.1668 0.88821   5 0.39722 0.7612 0.424, 2.682 -0.17
BXD48a m 2.416 2.0511   3 1.1842 0.849 0.226, 4.292 0.89
BXD49 m 2.3908 1.1393   5 0.50949 0.4765 0.84, 3.586 0.87
BXD51 m 0.23267 0.17317   3 0.09998 0.7443 0.106, 0.43 -0.97
BXD53 m 1.4765 1.113   4 0.55648 0.7538 0.006, 2.6 0.09
BXD55 m 0.7332 0.34196   5 0.15293 0.4664 0.314, 1.07 -0.54
BXD6 m 0.6805 0.43081   4 0.2154 0.6331 0.064, 1.048 -0.59
BXD62 m 0.484 0.4702   4 0.2351 0.9715 0.12, 1.14 -0.76
BXD63 m 0.78533 0.84615   3 0.48853 1.0774 0.02, 1.694 -0.5
BXD64 m 1.8196 0.19064   5 0.08526 0.1048 1.536, 2.066 0.38
BXD66 m 0.214 0.13355   3 0.07711 0.6241 0.098, 0.36 -0.99
BXD67 m 1.757 0.25012   4 0.12506 0.1424 1.528, 2.094 0.33
BXD69 m 3.1008 1.1728   5 0.5245 0.3782 2.232, 5.088 1.48
BXD73 m 4.558 2.2865   4 1.1432 0.5016 2.056, 7.578 2.72
BXD75 m 2.7612 2.5561   5 1.1431 0.9257 0.49, 5.962 1.19
BXD77 m 1.478 1.2437   5 0.5562 0.8415 0.278, 3.214 0.09
BXD79 m 1.031 0.43071   4 0.21535 0.4178 0.41, 1.394 -0.29
BXD8 m 0.8484 0.36898   5 0.16501 0.4349 0.462, 1.338 -0.45
BXD81 m 0.35 0.36204   2   0.256 1.0344 0.094, 0.606 -0.87
BXD84 m 0.7604 0.35234   5 0.15757 0.4634 0.424, 1.264 -0.52
BXD87 m 1.8108 0.87755   5 0.39245 0.4846 0.744, 3.114 0.38
BXD89 m 0.7755 0.74999   4 0.375 0.9671 0.204, 1.866 -0.51
BXD90 m 0.116 0.06713   4 0.03357 0.5787 0.054, 0.178 -1.07
C57BL/6J m 4.9624 3.1931   5 1.428 0.6435 1.962, 9.75 3.06
DBA/2J m 0.066 0.07071   2   0.05 1.0714 0.016, 0.116 -1.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.9524 0.5252988342 1.9934189923 -0.0886189923
BXD100 m 0.8132 0.5252988342 1.8542189923 -0.2278189923
BXD11 m 0.855 0.5873019508 2.0188946163 -0.3088946163
BXD12 m 1.0173333333 0.6781578788 2.3612830734 -0.3266164067
BXD27 m 0.53959 0.5873019508 1.7034846163 -0.6243046163
BXD32 m 2.3864 0.5252988342 3.4274189923 1.3453810077
BXD34 m 1.6932 0.5252988342 2.7342189923 0.6521810077
BXD39 m 0.5066666667 0.6781578788 1.8506164067 -0.8372830734
BXD40 m 2.8655 0.5873019508 4.0293946163 1.7016053837
BXD45 m 0.5195 0.5873019508 1.6833946163 -0.6443946163
BXD48 m 1.1668 0.5252988342 2.2078189923 0.1257810077
BXD48a m 2.416 0.6781578788 3.7599497401 1.0720502599
BXD49 m 2.3908 0.5252988342 3.4318189923 1.3497810077
BXD51 m 0.2326666667 0.6781578788 1.5766164067 -1.1112830734
BXD53 m 1.4765 0.5873019508 2.6403946163 0.3126053837
BXD55 m 0.7332 0.5252988342 1.7742189923 -0.3078189923
BXD6 m 0.6805 0.5873019508 1.8443946163 -0.4833946163
BXD62 m 0.484 0.5873019508 1.6478946163 -0.6798946163
BXD63 m 0.7853333333 0.6781578788 2.1292830734 -0.5586164067
BXD64 m 1.8196 0.5252988342 2.8606189923 0.7785810077
BXD66 m 0.214 0.6781578788 1.5579497401 -1.1299497401
BXD67 m 1.757 0.5873019508 2.9208946163 0.5931053837
BXD69 m 3.1008 0.5252988342 4.1418189923 2.0597810077
BXD73 m 4.558 0.5873019508 5.7218946163 3.3941053837
BXD75 m 2.7612 0.5252988342 3.8022189923 1.7201810077
BXD77 m 1.478 0.5252988342 2.5190189923 0.4369810077
BXD79 m 1.031 0.5873019508 2.1948946163 -0.1328946163
BXD8 m 0.8484 0.5252988342 1.8894189923 -0.1926189923
BXD81 m 0.35 0.8305703841 1.9959955516 -1.2959955516
BXD84 m 0.7604 0.5252988342 1.8014189923 -0.2806189923
BXD87 m 1.8108 0.5252988342 2.8518189923 0.7697810077
BXD89 m 0.7755 0.5873019508 1.9393946163 -0.3883946163
BXD90 m 0.116 0.5873019508 1.2798946163 -1.0478946163
C57BL/6J m 4.9624 0.5252988342 6.0034189923 3.9213810077
DBA/2J m 0.066 0.8305703841 1.7119955516 -1.5799955516




  GWAS USING LINEAR MIXED MODELS