Project measure / variable:   Schoonjans1   DCA_plasma_t60_CD

ID, description, units MPD:112730   DCA_plasma_t60_CD   plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means45.249   ng/mL
Median of the strain means35.662   ng/mL
SD of the strain means± 36.547
Coefficient of variation (CV)0.8077
Min–max range of strain means0.236   –   144.9   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 211964.1037 6234.2383 7.7683 < 0.0001
Residuals 125 100315.4842 802.5239


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 79.09 13.679   5 6.1173 0.173 64.27, 100.1 0.93
BXD100 m 14.714 5.1092   5 2.2849 0.3472 8.032, 21.818 -0.84
BXD11 m 16.587 9.9861   4 4.9931 0.602 7.93, 29.44 -0.78
BXD12 m 8.0987 1.696   3 0.9792 0.2094 7.064, 10.056 -1.02
BXD27 m 35.48 27.113   4 13.556 0.7642 14.806, 74.63 -0.27
BXD32 m 63.89 28.12   5 12.576 0.4401 31.014, 101.1 0.51
BXD34 m 15.709 0.92782   5 0.41493 0.0591 14.66, 17.012 -0.81
BXD39 m 20.361 2.5131   3 1.4509 0.1234 18.072, 23.05 -0.68
BXD40 m 14.371 4.1002   4 2.0501 0.2853 8.586, 17.404 -0.84
BXD43 m 7.2117 3.4866   7 1.3178 0.4835 1.558, 11.94 -1.04
BXD45 m 52.03 15.871   4 7.9356 0.305 35.506, 69.47 0.19
BXD48 m 98.1 41.508   5 18.563 0.4231 52.17, 161.2 1.45
BXD48a m 23.864 11.722   4 5.8611 0.4912 9.026, 35.43 -0.59
BXD49 m 59.69 37.226   5 16.648 0.6237 25.02, 120.2 0.4
BXD51 m 37.471 22.426   4 11.213 0.5985 16.052, 68.18 -0.21
BXD53 m 35.845 17.71   4 8.8551 0.4941 21.526, 61.68 -0.26
BXD55 m 68.27 18.761   5 8.3901 0.2748 53.64, 101.0 0.63
BXD6 m 0.236 0.0   1   0.0 0.0 0.236, 0.236 -1.23
BXD62 m 83.66 43.244   5 19.339 0.5169 22.488, 129.6 1.05
BXD63 m 69.58 25.874   4 12.937 0.3719 36.05, 94.9 0.67
BXD64 m 7.656 1.9866   5 0.88845 0.2595 5.268, 10.402 -1.03
BXD66 m 10.861 5.5161   5 2.4669 0.5079 4.992, 17.924 -0.94
BXD67 m 10.597 7.9221   4 3.9611 0.7476 3.254, 20.33 -0.95
BXD69 m 64.53 41.385   5 18.508 0.6414 26.568, 131.4 0.53
BXD73 m 115.4 28.383   4 14.191 0.2461 85.29, 142.8 1.92
BXD75 m 70.79 16.481   5 7.3707 0.2328 56.17, 89.49 0.7
BXD77 m 16.684 12.884   5 5.7621 0.7723 5.404, 38.584 -0.78
BXD79 m 83.26 70.68   5 31.607 0.8488 4.86, 187.1 1.04
BXD8 m 15.457 7.6776   5 3.4335 0.4967 4.29, 25.78 -0.82
BXD81 m 62.56 57.93   3 33.447 0.926 20.816, 128.7 0.47
BXD84 m 41.78 15.459   5 6.9133 0.37 29.572, 65.55 -0.09
BXD87 m 144.9 61.89   5 27.677 0.4272 104.0, 253.6 2.73
BXD89 m 20.765 16.721   5 7.4777 0.8052 6.904, 47.62 -0.67
BXD90 m 11.083 13.783   5 6.1641 1.2437 3.362, 35.514 -0.93
C57BL/6J m 114.7 45.236   5 20.23 0.3944 54.74, 168.4 1.9
DBA/2J m 33.7 26.397   4 13.198 0.7833 8.288, 70.13 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 79.088 12.669047902 104.1616181462 54.0143818538
BXD100 m 14.7144 12.669047902 39.7880181462 -10.3592181462
BXD11 m 16.587 14.1644261595 44.6201573084 -11.4461573084
BXD12 m 8.0986666667 16.3556705122 40.4685685031 -24.2712351698
BXD27 m 35.48025 14.1644261595 63.5134073084 7.4470926916
BXD32 m 63.8948 12.669047902 88.9684181462 38.8211818538
BXD34 m 15.7092 12.669047902 40.7828181462 -9.3644181462
BXD39 m 20.3606666667 16.3556705122 52.7305685031 -12.0092351698
BXD40 m 14.3715 14.1644261595 42.4046573084 -13.6616573084
BXD43 m 7.2117142857 10.7072997377 28.4027893434 -13.979360772
BXD45 m 52.031 14.1644261595 80.0641573084 23.9978426916
BXD48 m 98.102 12.669047902 123.1756181462 73.0283818538
BXD48a m 23.8635 14.1644261595 51.8966573084 -4.1696573084
BXD49 m 59.6896 12.669047902 84.7632181462 34.6159818538
BXD51 m 37.471 14.1644261595 65.5041573084 9.4378426916
BXD53 m 35.845 14.1644261595 63.8781573084 7.8118426916
BXD55 m 68.272 12.669047902 93.3456181462 43.1983818538
BXD62 m 83.6616 12.669047902 108.7352181462 58.5879818538
BXD63 m 69.575 14.1644261595 97.6081573084 41.5418426916
BXD64 m 7.656 12.669047902 32.7296181462 -17.4176181462
BXD66 m 10.8612 12.669047902 35.9348181462 -14.2124181462
BXD67 m 10.597 14.1644261595 38.6301573084 -17.4361573084
BXD69 m 64.5272 12.669047902 89.6008181462 39.4535818538
BXD73 m 115.35 14.1644261595 143.3831573084 87.3168426916
BXD75 m 70.792 12.669047902 95.8656181462 45.7183818538
BXD77 m 16.684 12.669047902 41.7576181462 -8.3896181462
BXD79 m 83.2648 12.669047902 108.3384181462 58.1911818538
BXD8 m 15.4572 12.669047902 40.5308181462 -9.6164181462
BXD81 m 62.56 16.3556705122 94.9299018365 30.1900981635
BXD84 m 41.7804 12.669047902 66.8540181462 16.7067818538
BXD87 m 144.88 12.669047902 169.9536181462 119.8063818538
BXD89 m 20.7652 12.669047902 45.8388181462 -4.3084181462
BXD90 m 11.0828 12.669047902 36.1564181462 -13.9908181462
C57BL/6J m 114.708 12.669047902 139.7816181462 89.6343818538
DBA/2J m 33.7005 14.1644261595 61.7336573084 5.6673426916




  GWAS USING LINEAR MIXED MODELS