Project measure / variable:   Schoonjans1   CDCA_plasma_t60_HFD

ID, description, units MPD:112729   CDCA_plasma_t60_HFD   plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means2.517   ng/mL
Median of the strain means1.536   ng/mL
SD of the strain means± 4.2391
Coefficient of variation (CV)1.6842
Min–max range of strain means0.1685   –   25.718   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 3060.7651 87.4504 1.3 0.1524
Residuals 114 7668.8164 67.2703


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.008 0.6543   5 0.29261 0.6491 0.396, 1.848 -0.36
BXD100 m 0.6 0.39356   7 0.14875 0.6559 0.002, 1.252 -0.45
BXD11 m 1.246 0.51103   3 0.29505 0.4101 0.942, 1.836 -0.3
BXD12 m 3.068 2.8692   4 1.4346 0.9352 0.778, 7.266 0.13
BXD27 m 4.6684 8.8394   5 3.9531 1.8935 0.006, 20.46 0.51
BXD32 m 1.2105 0.65866   4 0.32933 0.5441 0.558, 1.932 -0.31
BXD34 m 0.897 0.84166   4 0.42083 0.9383 0.08, 1.894 -0.38
BXD39 m 2.0567 2.2849   3 1.3192 1.111 0.24, 4.622 -0.11
BXD40 m 4.827 0.499   4 0.2495 0.1034 4.276, 5.482 0.54
BXD43 m 0.357 0.3182   2   0.225 0.8913 0.132, 0.582 -0.51
BXD45 m 1.7224 0.57835   5 0.25864 0.3358 1.008, 2.268 -0.19
BXD48 m 1.4648 1.6494   5 0.73761 1.126 0.248, 4.32 -0.25
BXD48a m 2.535 0.56802   4 0.28401 0.2241 1.706, 2.994 0.0
BXD49 m 25.718 41.463   5 18.543 1.6122 1.026, 98.1 5.47
BXD51 m 1.915 2.4565   2   1.737 1.2828 0.178, 3.652 -0.14
BXD53 m 1.7848 1.0193   5 0.45585 0.5711 0.576, 2.97 -0.17
BXD55 m 4.1496 3.1174   5 1.3941 0.7512 1.55, 8.078 0.39
BXD6 m 1.6072 1.6864   5 0.75416 1.0493 0.148, 4.346 -0.21
BXD62 m 6.111 8.1831   4 4.0915 1.3391 0.622, 17.94 0.85
BXD63 m 0.51 0.17615   5 0.07878 0.3454 0.31562, 0.726 -0.47
BXD64 m 1.162 1.4891   5 0.66596 1.2815 0.324, 3.806 -0.32
BXD66 m 0.38467 0.03349   3 0.01933 0.0871 0.346, 0.404 -0.5
BXD67 m 0.7386 0.58305   5 0.26075 0.7894 0.108, 1.425 -0.42
BXD69 m 5.502 6.2962   4 3.1481 1.1443 1.71, 14.918 0.7
BXD73 m 1.8153 0.93994   3 0.54268 0.5178 0.772, 2.596 -0.17
BXD75 m 1.344 1.0727   4 0.53636 0.7982 0.334, 2.68 -0.28
BXD77 m 1.2352 0.83362   5 0.3728 0.6749 0.348, 2.392 -0.3
BXD79 m 1.968 1.3625   5 0.60935 0.6923 0.418, 4.102 -0.13
BXD8 m 1.0227 0.85309   3 0.49253 0.8342 0.11, 1.8 -0.35
BXD81 m 1.8172 1.1921   5 0.53313 0.656 0.408, 3.446 -0.17
BXD84 m 0.1685 0.12002   4 0.06001 0.7123 0.082, 0.344 -0.55
BXD87 m 1.3425 0.69327   4 0.34663 0.5164 0.686, 2.31 -0.28
BXD89 m 1.6788 1.4074   5 0.6294 0.8383 0.504, 4.044 -0.2
BXD90 m 1.0369 0.56763   4 0.28382 0.5474 0.52857, 1.784 -0.35
C57BL/6J m 1.6634 0.41486   2   0.29335 0.2494 1.37, 1.9567 -0.2
DBA/2J m 0.27459 0.01563   3 0.00902575 0.0569 0.26176, 0.292 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.008 3.667978174 8.2742365118 -6.2582365118
BXD100 m 0.6 3.10000736 6.7410907038 -5.5410907038
BXD11 m 1.246 4.7353394607 10.626671 -8.134671
BXD12 m 3.068 4.1009242685 11.1918993905 -5.0558993905
BXD27 m 4.6684 3.667978174 11.9346365118 -2.5978365118
BXD32 m 1.2105 4.1009242685 9.3343993905 -6.9133993905
BXD34 m 0.897 4.1009242685 9.0208993905 -7.2268993905
BXD39 m 2.0566666667 4.7353394607 11.4373376667 -7.3240043333
BXD40 m 4.827 4.1009242685 12.9508993905 -3.2968993905
BXD43 m 0.357 5.7995827188 11.8459286975 -11.1319286975
BXD45 m 1.7224 3.667978174 8.9886365118 -5.5438365118
BXD48 m 1.4648 3.667978174 8.7310365118 -5.8014365118
BXD48a m 2.535 4.1009242685 10.6588993905 -5.5888993905
BXD49 m 25.7184 3.667978174 32.9846365118 18.4521634882
BXD51 m 1.915 5.7995827188 13.4039286975 -9.5739286975
BXD53 m 1.7848 3.667978174 9.0510365118 -5.4814365118
BXD55 m 4.1496 3.667978174 11.4158365118 -3.1166365118
BXD6 m 1.60716 3.667978174 8.8733965118 -5.6590765118
BXD62 m 6.111 4.1009242685 14.2348993905 -2.0128993905
BXD63 m 0.51 3.667978174 7.7762365118 -6.7562365118
BXD64 m 1.162 3.667978174 8.4282365118 -6.1042365118
BXD66 m 0.3846666667 4.7353394607 9.7653376667 -8.9960043333
BXD67 m 0.7386 3.667978174 8.0048365118 -6.5276365118
BXD69 m 5.502 4.1009242685 13.6258993905 -2.6218993905
BXD73 m 1.8153333333 4.7353394607 11.1960043333 -7.5653376667
BXD75 m 1.344 4.1009242685 9.4678993905 -6.7798993905
BXD77 m 1.2352 3.667978174 8.5014365118 -6.0310365118
BXD79 m 1.968 3.667978174 9.2342365118 -5.2982365118
BXD8 m 1.0226666667 4.7353394607 10.4033376667 -8.3580043333
BXD81 m 1.8172 3.667978174 9.0834365118 -5.4490365118
BXD84 m 0.1685 4.1009242685 8.2923993905 -7.9553993905
BXD87 m 1.3425 4.1009242685 9.4663993905 -6.7813993905
BXD89 m 1.6788 3.667978174 8.9450365118 -5.5874365118
BXD90 m 1.036885 4.1009242685 9.1607843905 -7.0870143905
C57BL/6J m 1.66335 5.7995827188 13.1522786975 -9.8255786975
DBA/2J m 0.2745866667 4.7353394607 9.6552576667 -9.1060843333




  GWAS USING LINEAR MIXED MODELS