Project measure / variable:   Schoonjans1   bMCA_plasma_t60_HFD

ID, description, units MPD:112725   bMCA_plasma_t60_HFD   plasma bile acid β-muricholic acid, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid β-muricholic acid, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means40.583   ng/mL
Median of the strain means24.85   ng/mL
SD of the strain means± 42.353
Coefficient of variation (CV)1.0436
Min–max range of strain means7.9668   –   222.1   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 264415.6459 7554.7327 1.9406 0.0044
Residuals 121 471042.5013 3892.9132


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 24.648 10.088   5 4.5117 0.4093 12.242, 36.814 -0.38
BXD100 m 15.832 11.667   9 3.889 0.7369 2.078, 41.828 -0.58
BXD11 m 53.07 22.01   3 12.707 0.4148 27.88, 68.6 0.29
BXD12 m 84.26 55.99   4 27.995 0.6645 32.688, 155.6 1.03
BXD27 m 49.183 48.754   5 21.803 0.9913 8.462, 113.9 0.2
BXD32 m 35.346 15.43   4 7.7149 0.4365 22.172, 52.83 -0.12
BXD34 m 25.052 10.794   4 5.3969 0.4309 13.43, 39.11 -0.37
BXD39 m 14.622 8.9566   3 5.1711 0.6125 8.292, 24.87 -0.61
BXD40 m 88.22 25.586   4 12.793 0.29 58.93, 114.9 1.12
BXD43 m 23.89 13.888   5 6.2109 0.5813 9.782, 46.15 -0.39
BXD45 m 32.151 11.755   5 5.2569 0.3656 17.74, 46.738 -0.2
BXD48 m 13.165 10.853   5 4.8536 0.8244 5.89, 31.194 -0.65
BXD48a m 21.055 7.7637   4 3.8819 0.3687 11.886, 30.444 -0.46
BXD49 m 85.41 127.3   5 56.93 1.4906 21.052, 312.9 1.06
BXD51 m 8.5569 6.8544   3 3.9574 0.801 2.456, 15.974 -0.76
BXD53 m 10.645 5.3675   5 2.4004 0.5042 4.58, 18.502 -0.71
BXD55 m 48.45 31.87   5 14.253 0.6578 22.846, 100.8 0.19
BXD6 m 134.1 167.2   5 74.78 1.2468 7.612, 422.2 2.21
BXD62 m 222.1 277.3   4 138.6 1.2485 28.302, 622.0 4.29
BXD63 m 23.557 9.4512   5 4.2267 0.4012 12.856, 38.51 -0.4
BXD64 m 13.978 21.208   5 9.4845 1.5172 3.926, 51.9 -0.63
BXD66 m 9.5813 4.9783   3 2.8742 0.5196 5.474, 15.118 -0.73
BXD67 m 13.369 11.379   5 5.0888 0.8512 4.864, 32.616 -0.64
BXD69 m 20.65 10.655   4 5.3274 0.516 8.23, 29.99 -0.47
BXD73 m 68.13 19.514   3 11.266 0.2864 56.14, 90.65 0.65
BXD75 m 22.344 28.758   4 14.379 1.287 3.202, 64.39 -0.43
BXD77 m 40.279 52.92   5 23.665 1.3137 11.568, 134.3 -0.01
BXD79 m 72.34 39.967   5 17.874 0.5525 46.074, 142.9 0.75
BXD8 m 38.708 3.3859   3 1.9548 0.0875 35.018, 41.672 -0.04
BXD81 m 30.068 18.732   5 8.3771 0.623 10.66, 50.83 -0.25
BXD84 m 28.593 37.232   5 16.651 1.3022 3.678, 93.76 -0.28
BXD87 m 50.88 24.648   4 12.324 0.4844 19.288, 76.36 0.24
BXD89 m 13.408 6.7066   5 2.9993 0.5002 6.348, 23.044 -0.64
BXD90 m 7.9668 3.539   4 1.7695 0.4442 4.3393, 12.712 -0.77
C57BL/6J m 8.5146 1.402   2   0.99135 0.1647 7.5233, 9.506 -0.76
DBA/2J m 8.8767 3.6965   3 2.1342 0.4164 6.036, 13.056 -0.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 24.648 27.9030938579 79.8895340817 -30.5935340817
BXD100 m 15.8324444444 20.7977382163 57.0070529071 -25.3421640182
BXD11 m 53.0666666667 36.0227392731 124.3831805058 -18.2498471724
BXD12 m 84.2605 31.1966073244 146.022412694 22.498587306
BXD27 m 49.1828 27.9030938579 104.4243340817 -6.0587340817
BXD32 m 35.346 31.1966073244 97.107912694 -26.415912694
BXD34 m 25.052 31.1966073244 86.813912694 -36.709912694
BXD39 m 14.622 36.0227392731 85.9385138391 -56.6945138391
BXD40 m 88.2175 31.1966073244 149.979412694 26.455587306
BXD43 m 23.8896 27.9030938579 79.1311340817 -31.3519340817
BXD45 m 32.1508 27.9030938579 87.3923340817 -23.0907340817
BXD48 m 13.1648 27.9030938579 68.4063340817 -42.0767340817
BXD48a m 21.055 31.1966073244 82.816912694 -40.706912694
BXD49 m 85.408 27.9030938579 140.6495340817 30.1664659183
BXD51 m 8.5569 36.0227392731 79.8734138391 -62.7596138391
BXD53 m 10.6452 27.9030938579 65.8867340817 -44.5963340817
BXD55 m 48.4496 27.9030938579 103.6911340817 -6.7919340817
BXD6 m 134.1096 27.9030938579 189.3511340817 78.8680659183
BXD62 m 222.081 31.1966073244 283.842912694 160.319087306
BXD63 m 23.5568 27.9030938579 78.7983340817 -31.6847340817
BXD64 m 13.978 27.9030938579 69.2195340817 -41.2635340817
BXD66 m 9.5813333333 36.0227392731 80.8978471724 -61.7351805058
BXD67 m 13.3688 27.9030938579 68.6103340817 -41.8727340817
BXD69 m 20.65 31.1966073244 82.411912694 -41.111912694
BXD73 m 68.1333333333 36.0227392731 139.4498471724 -3.1831805058
BXD75 m 22.344 31.1966073244 84.105912694 -39.417912694
BXD77 m 40.2792 27.9030938579 95.5207340817 -14.9623340817
BXD79 m 72.3428 27.9030938579 127.5843340817 17.1012659183
BXD8 m 38.708 36.0227392731 110.0245138391 -32.6085138391
BXD81 m 30.0676 27.9030938579 85.3091340817 -25.1739340817
BXD84 m 28.5928 27.9030938579 83.8343340817 -26.6487340817
BXD87 m 50.885 31.1966073244 112.646912694 -10.876912694
BXD89 m 13.4076 27.9030938579 68.6491340817 -41.8339340817
BXD90 m 7.96675 31.1966073244 69.728662694 -53.795162694
C57BL/6J m 8.51465 44.1186651782 95.85918457 -78.82988457
DBA/2J m 8.8767333333 36.0227392731 80.1932471724 -62.4397805058




  GWAS USING LINEAR MIXED MODELS