Project measure / variable:   Schoonjans1   aMCA_plasma_t60_HFD

ID, description, units MPD:112723   aMCA_plasma_t60_HFD   plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means7.2864   ng/mL
Median of the strain means5.176   ng/mL
SD of the strain means± 6.2166
Coefficient of variation (CV)0.8532
Min–max range of strain means1.444   –   26.781   ng/mL
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 5487.6005 161.4 1.272 0.1772
Residuals 107 13576.8012 126.886


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.5832 1.8101   5 0.80952 0.5052 1.764, 5.954 -0.6
BXD100 m 2.3363 1.3764   6 0.56193 0.5891 1.186, 5.036 -0.8
BXD11 m 4.9147 3.7617   3 2.1718 0.7654 2.358, 9.234 -0.38
BXD12 m 16.444 20.056   4 10.028 1.2196 3.466, 45.946 1.47
BXD27 m 14.931 12.046   3 6.9546 0.8067 4.086, 27.896 1.23
BXD32 m 4.95 3.6429   4 1.8215 0.7359 1.882, 9.812 -0.38
BXD34 m 3.715 2.0111   4 1.0056 0.5414 1.216, 6.124 -0.57
BXD39 m 5.758 4.0035   3 2.3114 0.6953 1.458, 9.378 -0.25
BXD40 m 10.639 2.212   4 1.106 0.2079 8.072, 12.796 0.54
BXD43 m 1.444 0.15556   2   0.11 0.1077 1.334, 1.554 -0.94
BXD45 m 6.0936 1.7128   5 0.76597 0.2811 4.234, 8.044 -0.19
BXD48 m 7.1796 6.8915   5 3.082 0.9599 2.678, 19.39 -0.02
BXD48a m 8.298 4.8179   4 2.409 0.5806 3.716, 15.03 0.16
BXD49 m 7.9596 11.539   5 5.1602 1.4496 1.948, 28.576 0.11
BXD51 m 1.746 0.93904   2   0.664 0.5378 1.082, 2.41 -0.89
BXD53 m 3.7028 1.4482   5 0.64763 0.3911 2.398, 6.13 -0.58
BXD55 m 11.164 9.6744   5 4.3265 0.8665 2.478, 26.162 0.62
BXD6 m 15.606 8.0393   3 4.6415 0.5152 7.47, 23.545 1.34
BXD62 m 26.757 30.942   4 15.471 1.1564 2.484, 67.66 3.13
BXD63 m 3.4157 1.5516   5 0.69391 0.4543 2.2188, 5.6595 -0.62
BXD64 m 4.8428 6.748   5 3.0178 1.3934 1.216, 16.854 -0.39
BXD66 m 3.358 2.2663   3 1.3084 0.6749 1.594, 5.914 -0.63
BXD67 m 2.2173 1.4535   5 0.65 0.6555 1.14, 4.6344 -0.82
BXD69 m 6.0885 5.4341   4 2.7171 0.8925 2.008, 13.742 -0.19
BXD73 m 9.5393 2.3166   3 1.3375 0.2428 6.91, 11.28 0.36
BXD75 m 3.8655 3.5752   4 1.7876 0.9249 1.01, 8.82 -0.55
BXD77 m 26.781 40.436   5 18.083 1.5099 4.23, 98.88 3.14
BXD79 m 5.6016 4.492   5 2.0089 0.8019 2.3, 13.476 -0.27
BXD8 m 2.1493 1.2005   3 0.69309 0.5585 1.204, 3.5 -0.83
BXD81 m 9.2924 6.9942   5 3.1279 0.7527 1.89, 17.402 0.32
BXD84 m 10.969 13.492   4 6.7461 1.23 1.266, 30.376 0.59
BXD87 m 3.121 2.0646   4 1.0323 0.6615 1.302, 5.218 -0.67
BXD89 m 3.476 1.2622   5 0.56445 0.3631 2.058, 5.074 -0.61
BXD90 m 3.505 1.6654   4 0.83272 0.4752 1.8107, 5.164 -0.61
C57BL/6J m 5.402 0.35072   2   0.248 0.0649 5.154, 5.65 -0.3
DBA/2J m 1.466 0.0   1   0.0 0.0 1.466, 1.466 -0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.5832 5.0375786401 13.5696121221 -6.4032121221
BXD100 m 2.3363333333 4.598659094 11.4526386464 -6.7799719797
BXD11 m 4.9146666667 6.5034860595 17.8070692791 -7.9777359458
BXD12 m 16.444 5.6321841407 27.6091481782 5.2788518218
BXD27 m 14.9313333333 6.5034860595 27.8237359458 2.0389307209
BXD32 m 4.95 5.6321841407 16.1151481782 -6.2151481782
BXD34 m 3.715 5.6321841407 14.8801481782 -7.4501481782
BXD39 m 5.758 6.5034860595 18.6504026124 -7.1344026124
BXD40 m 10.6385 5.6321841407 21.8036481782 -0.5266481782
BXD43 m 1.444 7.9651111975 17.2339039795 -14.3459039795
BXD45 m 6.0936 5.0375786401 16.0800121221 -3.8928121221
BXD48 m 7.1796 5.0375786401 17.1660121221 -2.8068121221
BXD48a m 8.298 5.6321841407 19.4631481782 -2.8671481782
BXD49 m 7.9596 5.0375786401 17.9460121221 -2.0268121221
BXD51 m 1.746 7.9651111975 17.5359039795 -14.0439039795
BXD53 m 3.7028 5.0375786401 13.6892121221 -6.2836121221
BXD55 m 11.1644 5.0375786401 21.1508121221 1.1779878779
BXD6 m 15.6056666667 6.5034860595 28.4980692791 2.7132640542
BXD62 m 26.7575 5.6321841407 37.9226481782 15.5923518218
BXD63 m 3.41566 5.0375786401 13.4020721221 -6.5707521221
BXD64 m 4.8428 5.0375786401 14.8292121221 -5.1436121221
BXD66 m 3.358 6.5034860595 16.2504026124 -9.5344026124
BXD67 m 2.21728 5.0375786401 12.2036921221 -7.7691321221
BXD69 m 6.0885 5.6321841407 17.2536481782 -5.0766481782
BXD73 m 9.5393333333 6.5034860595 22.4317359458 -3.3530692791
BXD75 m 3.8655 5.6321841407 15.0306481782 -7.2996481782
BXD77 m 26.7812 5.0375786401 36.7676121221 16.7947878779
BXD79 m 5.6016 5.0375786401 15.5880121221 -4.3848121221
BXD8 m 2.1493333333 6.5034860595 15.0417359458 -10.7430692791
BXD81 m 9.2924 5.0375786401 19.2788121221 -0.6940121221
BXD84 m 10.969 5.6321841407 22.1341481782 -0.1961481782
BXD87 m 3.121 5.6321841407 14.2861481782 -8.0441481782
BXD89 m 3.476 5.0375786401 13.4624121221 -6.5104121221
BXD90 m 3.505 5.6321841407 14.6701481782 -7.6601481782
C57BL/6J m 5.402 7.9651111975 21.1919039795 -10.3879039795




  GWAS USING LINEAR MIXED MODELS