Project measure / variable:   Schoonjans1   keto_DCA_plasma_t60_HFD

ID, description, units MPD:112721   keto_DCA_plasma_t60_HFD   plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   35 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means1.4937   ng/mL
Median of the strain means0.948   ng/mL
SD of the strain means± 1.875
Coefficient of variation (CV)1.2552
Min–max range of strain means0.212   –   10.484   ng/mL
Mean sample size per strain3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 31 522.8682 16.8667 0.891 0.632
Residuals 84 1590.111 18.9299


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.846 1.772   4 0.88598 0.9599 0.542, 4.45 0.19
BXD100 m 0.366 0.24619   5 0.1101 0.6726 0.208, 0.802 -0.6
BXD11 m 0.73133 0.72374   3 0.41785 0.9896 0.278, 1.566 -0.41
BXD12 m 1.7707 0.954   3 0.55079 0.5388 0.68, 2.45 0.15
BXD27 m 0.83733 0.67424   3 0.38927 0.8052 0.278, 1.586 -0.35
BXD32 m 0.6165 0.47937   4 0.23969 0.7776 0.208, 1.19 -0.47
BXD34 m 0.43933 0.26746   3 0.15442 0.6088 0.276, 0.748 -0.56
BXD39 m 2.315 1.7126   2   1.211 0.7398 1.104, 3.526 0.44
BXD40 m 1.0535 0.39139   4 0.19569 0.3715 0.64, 1.552 -0.23
BXD45 m 0.6304 0.35792   5 0.16007 0.5678 0.25, 1.202 -0.46
BXD48 m 0.948 1.3297   5 0.59465 1.4026 0.222, 3.31 -0.29
BXD48a m 1.3995 0.66526   4 0.33263 0.4754 0.56, 2.17 -0.05
BXD49 m 10.484 18.358   5 8.2101 1.7512 1.148, 43.264 4.79
BXD51 m 0.496 0.0   1   0.0 0.0 0.496, 0.496 -0.53
BXD53 m 0.5955 0.39049   4 0.19524 0.6557 0.216, 1.138 -0.48
BXD55 m 2.4548 2.5149   5 1.1247 1.0245 0.464, 6.316 0.51
BXD6 m 4.146 3.6285   4 1.8143 0.8752 0.292, 8.6159 1.41
BXD62 m 4.9007 6.3769   3 3.6817 1.3012 0.29, 12.178 1.82
BXD63 m 0.41486 0.01993   3 0.0115 0.048 0.392, 0.42857 -0.58
BXD64 m 2.082 0.0   1   0.0 0.0 2.082, 2.082 0.31
BXD66 m 0.29267 0.11976   3 0.06914 0.4092 0.21, 0.43 -0.64
BXD67 m 0.38125 0.25633   2   0.18125 0.6723 0.2, 0.5625 -0.59
BXD69 m 2.115 2.5021   4 1.2511 1.183 0.372, 5.78 0.33
BXD73 m 0.96133 0.49894   3 0.28807 0.519 0.424, 1.41 -0.28
BXD75 m 1.7087 1.1921   3 0.68827 0.6977 0.382, 2.69 0.11
BXD77 m 1.6776 3.0792   5 1.377 1.8355 0.25, 7.184 0.1
BXD79 m 0.5732 0.55752   5 0.24933 0.9726 0.272, 1.568 -0.49
BXD8 m 0.702 0.42992   2   0.304 0.6124 0.398, 1.006 -0.42
BXD81 m 1.0828 0.81632   5 0.36507 0.7539 0.224, 2.068 -0.22
BXD84 m 0.57933 0.14643   3 0.08454 0.2528 0.412, 0.684 -0.49
BXD87 m 1.044 1.166   4 0.58298 1.1168 0.34, 2.778 -0.24
BXD89 m 0.69 0.37139   4 0.1857 0.5383 0.308, 1.144 -0.43
BXD90 m 0.446 0.23193   2   0.164 0.52 0.282, 0.61 -0.56
C57BL/6J m 1.287 0.03818   2   0.027 0.0297 1.26, 1.314 -0.11
DBA/2J m 0.212 0.0   1   0.0 0.0 0.212, 0.212 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.846 2.1754248622 6.1720709107 -2.4800709107
BXD100 m 0.366 1.9457591487 4.2353554527 -3.5033554527
BXD11 m 0.7313333333 2.5119642596 5.726649743 -4.2639830763
BXD12 m 1.7706666667 2.5119642596 6.7659830763 -3.224649743
BXD27 m 0.8373333333 2.5119642596 5.832649743 -4.1579830763
BXD32 m 0.6165 2.1754248622 4.9425709107 -3.7095709107
BXD34 m 0.4393333333 2.5119642596 5.434649743 -4.5559830763
BXD39 m 2.315 3.076515344 8.4329881537 -3.8029881537
BXD40 m 1.0535 2.1754248622 5.3795709107 -3.2725709107
BXD45 m 0.6304 1.9457591487 4.4997554527 -3.2389554527
BXD48 m 0.948 1.9457591487 4.8173554527 -2.9213554527
BXD48a m 1.3995 2.1754248622 5.7255709107 -2.9265709107
BXD49 m 10.4836 1.9457591487 14.3529554527 6.6142445473
BXD53 m 0.5955 2.1754248622 4.9215709107 -3.7305709107
BXD55 m 2.4548 1.9457591487 6.3241554527 -1.4145554527
BXD6 m 4.145975 2.1754248622 8.4720459107 -0.1800959107
BXD62 m 4.9006666667 2.5119642596 9.8959830763 -0.094649743
BXD63 m 0.4148566667 2.5119642596 5.4101730763 -4.580459743
BXD66 m 0.2926666667 2.5119642596 5.2879830763 -4.702649743
BXD67 m 0.38125 3.076515344 6.4992381537 -5.7367381537
BXD69 m 2.115 2.1754248622 6.4410709107 -2.2110709107
BXD73 m 0.9613333333 2.5119642596 5.956649743 -4.0339830763
BXD75 m 1.7086666667 2.5119642596 6.7039830763 -3.286649743
BXD77 m 1.6776 1.9457591487 5.5469554527 -2.1917554527
BXD79 m 0.5732 1.9457591487 4.4425554527 -3.2961554527
BXD8 m 0.702 3.076515344 6.8199881537 -5.4159881537
BXD81 m 1.0828 1.9457591487 4.9521554527 -2.7865554527
BXD84 m 0.5793333333 2.5119642596 5.574649743 -4.4159830763
BXD87 m 1.044 2.1754248622 5.3700709107 -3.2820709107
BXD89 m 0.69 2.1754248622 5.0160709107 -3.6360709107
BXD90 m 0.446 3.076515344 6.5639881537 -5.6719881537
C57BL/6J m 1.287 3.076515344 7.4049881537 -4.8309881537




  GWAS USING LINEAR MIXED MODELS