Project measure / variable:   Schoonjans1   keto_DCA_plasma_t60_CD

ID, description, units MPD:112720   keto_DCA_plasma_t60_CD   plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means5.2281   ng/mL
Median of the strain means1.3407   ng/mL
SD of the strain means± 8.5376
Coefficient of variation (CV)1.633
Min–max range of strain means0.238   –   39.036   ng/mL
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 31 11324.6064 365.3099 1.8859 0.0104
Residuals 94 18208.1888 193.7041


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 6.3468 13.004   5 5.8156 2.0489 0.204, 29.602 0.13
BXD100 m 0.5755 0.30153   4 0.15077 0.5239 0.34, 1.01 -0.54
BXD11 m 0.26733 0.07162   3 0.04135 0.2679 0.224, 0.35 -0.58
BXD12 m 11.831 18.648   3 10.766 1.5761 0.314, 33.346 0.77
BXD27 m 1.3174 1.0608   4 0.53039 0.8052 0.46364, 2.84 -0.46
BXD32 m 5.506 4.8048   5 2.1488 0.8726 0.82, 12.616 0.03
BXD34 m 2.0476 1.3615   5 0.60888 0.6649 0.694, 4.252 -0.37
BXD39 m 0.584 0.0   1   0.0 0.0 0.584, 0.584 -0.54
BXD40 m 5.7505 6.0624   4 3.0312 1.0542 0.908, 14.606 0.06
BXD43 m 0.878 0.0   1   0.0 0.0 0.878, 0.878 -0.51
BXD45 m 7.584 13.404   4 6.7022 1.7674 0.482, 27.676 0.28
BXD48 m 1.3724 0.68519   5 0.30642 0.4993 0.616, 2.182 -0.45
BXD48a m 4.338 2.9529   4 1.4765 0.6807 0.774, 7.698 -0.1
BXD49 m 39.036 48.886   5 21.863 1.2523 2.542, 117.8 3.96
BXD51 m 0.396 0.15143   3 0.08743 0.3824 0.294, 0.57 -0.57
BXD53 m 0.904 0.74265   4 0.37133 0.8215 0.236, 1.902 -0.51
BXD55 m 21.163 11.642   5 5.2063 0.5501 5.416, 37.01 1.87
BXD6 m 26.206 22.67   5 10.138 0.8651 5.42, 57.76 2.46
BXD62 m 0.8408 0.70462   5 0.31511 0.838 0.242, 1.994 -0.51
BXD63 m 0.566 0.16357   4 0.08178 0.289 0.332, 0.71 -0.55
BXD64 m 0.386 0.0   1   0.0 0.0 0.386, 0.386 -0.57
BXD66 m 0.238 0.04525   2   0.032 0.1901 0.206, 0.27 -0.58
BXD67 m 0.359 0.04101   2   0.029 0.1142 0.33, 0.388 -0.57
BXD69 m 2.5748 2.5881   5 1.1575 1.0052 0.542, 6.472 -0.31
BXD73 m 4.3885 3.933   4 1.9665 0.8962 0.906, 9.99 -0.1
BXD75 m 1.0772 1.1213   5 0.50146 1.0409 0.272, 2.936 -0.49
BXD77 m 6.4868 8.8987   5 3.9796 1.3718 0.356, 20.986 0.15
BXD79 m 2.014 1.996   5 0.89265 0.9911 0.22, 5.01 -0.38
BXD8 m 0.738 0.0   1   0.0 0.0 0.738, 0.738 -0.53
BXD81 m 1.364 1.2473   2   0.882 0.9145 0.482, 2.246 -0.45
BXD84 m 0.259 0.00707107   2   0.005 0.0273 0.254, 0.264 -0.58
BXD87 m 7.6772 5.6112   5 2.5094 0.7309 3.644, 17.28 0.29
BXD89 m 1.144 0.80563   3 0.46513 0.7042 0.218, 1.684 -0.48
BXD90 m 1.207 0.4879   2   0.345 0.4042 0.862, 1.552 -0.47
C57BL/6J m 20.183 28.959   5 12.951 1.4348 2.166, 71.15 1.75
DBA/2J m 0.603 0.06647   2   0.047 0.1102 0.556, 0.65 -0.54


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 6.3468 6.2242129743 18.7051207675 -6.0115207675
BXD100 m 0.5755 6.9588816584 14.392522662 -13.241522662
BXD11 m 0.2673333333 8.0354243975 16.2218568399 -15.6871901733
BXD12 m 11.8313333333 8.0354243975 27.7858568399 -4.1231901733
BXD27 m 1.31741 6.9588816584 15.134432662 -12.499612662
BXD32 m 5.506 6.2242129743 17.8643207675 -6.8523207675
BXD34 m 2.0476 6.2242129743 14.4059207675 -10.3107207675
BXD40 m 5.7505 6.9588816584 19.567522662 -8.066522662
BXD45 m 7.584 6.9588816584 21.401022662 -6.233022662
BXD48 m 1.3724 6.2242129743 13.7307207675 -10.9859207675
BXD48a m 4.338 6.9588816584 18.155022662 -9.479022662
BXD49 m 39.0356 6.2242129743 51.3939207675 26.6772792325
BXD51 m 0.396 8.0354243975 16.3505235066 -15.5585235066
BXD53 m 0.904 6.9588816584 14.721022662 -12.913022662
BXD55 m 21.1632 6.2242129743 33.5215207675 8.8048792325
BXD6 m 26.206 6.2242129743 38.5643207675 13.8476792325
BXD62 m 0.8408 6.2242129743 13.1991207675 -11.5175207675
BXD63 m 0.566 6.9588816584 14.383022662 -13.251022662
BXD66 m 0.238 9.8413448203 19.7782208402 -19.3022208402
BXD67 m 0.359 9.8413448203 19.8992208402 -19.1812208402
BXD69 m 2.5748 6.2242129743 14.9331207675 -9.7835207675
BXD73 m 4.3885 6.9588816584 18.205522662 -9.428522662
BXD75 m 1.0772 6.2242129743 13.4355207675 -11.2811207675
BXD77 m 6.4868 6.2242129743 18.8451207675 -5.8715207675
BXD79 m 2.014 6.2242129743 14.3723207675 -10.3443207675
BXD81 m 1.364 9.8413448203 20.9042208402 -18.1762208402
BXD84 m 0.259 9.8413448203 19.7992208402 -19.2812208402
BXD87 m 7.6772 6.2242129743 20.0355207675 -4.6811207675
BXD89 m 1.144 8.0354243975 17.0985235066 -14.8105235066
BXD90 m 1.207 9.8413448203 20.7472208402 -18.3332208402
C57BL/6J m 20.1832 6.2242129743 32.5415207675 7.8248792325
DBA/2J m 0.603 9.8413448203 20.1432208402 -18.9372208402




  GWAS USING LINEAR MIXED MODELS