Project measure / variable:   Schoonjans1   UDCA_plasma_t30_HFD

ID, description, units MPD:112715   UDCA_plasma_t30_HFD   plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   29 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested29 strains
Mean of the strain means5.0677   ng/mL
Median of the strain means3.596   ng/mL
SD of the strain means± 4.9332
Coefficient of variation (CV)0.9735
Min–max range of strain means1.3   –   26.456   ng/mL
Mean sample size per strain2.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 18 1730.8723 96.1596 1.1986 0.3086
Residuals 39 3128.8167 80.2261


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.693 0.29557   2   0.209 0.08 3.484, 3.902 -0.28
BXD100 m 4.04 0.0   1   0.0 0.0 4.04, 4.04 -0.21
BXD11 m 14.503 8.3651   2   5.915 0.5768 8.588, 20.418 1.91
BXD12 m 4.9507 3.3798   3 1.9513 0.6827 1.88, 8.572 -0.02
BXD27 m 7.2807 6.8315   3 3.9441 0.9383 2.232, 15.054 0.45
BXD32 m 2.47 0.03394   2   0.024 0.0137 2.446, 2.494 -0.53
BXD34 m 2.53 0.0   1   0.0 0.0 2.53, 2.53 -0.51
BXD39 m 2.658 0.0   1   0.0 0.0 2.658, 2.658 -0.49
BXD40 m 5.672 3.2254   4 1.6127 0.5687 1.592, 8.488 0.12
BXD45 m 4.4076 2.0608   5 0.92164 0.4676 1.894, 6.678 -0.13
BXD48 m 2.496 0.0   1   0.0 0.0 2.496, 2.496 -0.52
BXD48a m 2.183 0.732   4 0.366 0.3353 1.51, 3.17 -0.58
BXD49 m 26.456 35.644   3 20.579 1.3473 2.12, 67.37 4.34
BXD53 m 1.3 0.0   1   0.0 0.0 1.3, 1.3 -0.76
BXD55 m 3.3788 3.1393   5 1.404 0.9291 1.248, 8.86 -0.34
BXD6 m 4.616 2.257   3 1.3031 0.4889 2.01, 5.9421 -0.09
BXD62 m 8.7313 11.014   3 6.3592 1.2615 1.948, 21.44 0.74
BXD63 m 2.444 0.0   1   0.0 0.0 2.444, 2.444 -0.53
BXD64 m 3.596 0.0   1   0.0 0.0 3.596, 3.596 -0.3
BXD69 m 6.854 2.011   2   1.422 0.2934 5.432, 8.276 0.36
BXD73 m 2.766 2.0308   2   1.436 0.7342 1.33, 4.202 -0.47
BXD75 m 6.086 0.0   1   0.0 0.0 6.086, 6.086 0.21
BXD77 m 1.595 0.39457   2   0.279 0.2474 1.316, 1.874 -0.7
BXD79 m 3.9112 0.96351   5 0.4309 0.2463 2.92, 5.214 -0.23
BXD81 m 2.004 0.0   1   0.0 0.0 2.004, 2.004 -0.62
BXD84 m 7.571 5.91   2   4.179 0.7806 3.392, 11.75 0.51
BXD87 m 2.941 0.98005   2   0.693 0.3332 2.248, 3.634 -0.43
BXD89 m 2.5555 1.9638   4 0.98189 0.7685 1.226, 5.412 -0.51
BXD90 m 3.274 0.0   1   0.0 0.0 3.274, 3.274 -0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.693 6.3334851578 16.5036829209 -9.1176829209
BXD11 m 14.503 6.3334851578 27.3136829209 1.6923170791
BXD12 m 4.9506666667 5.1712689767 15.4105454709 -5.5092121376
BXD27 m 7.2806666667 5.1712689767 17.7405454709 -3.1792121376
BXD32 m 2.47 6.3334851578 15.2806829209 -10.3406829209
BXD40 m 5.672 4.4784503036 14.730520765 -3.386520765
BXD45 m 4.4076 4.0056477251 12.5097872824 -3.6945872824
BXD48a m 2.183 4.4784503036 11.241520765 -6.875520765
BXD49 m 26.456 5.1712689767 36.9158788043 15.9961211957
BXD55 m 3.3788 4.0056477251 11.4809872824 -4.7233872824
BXD6 m 4.6159666667 5.1712689767 15.0758454709 -5.8439121376
BXD62 m 8.7313333333 5.1712689767 19.1912121376 -1.7285454709
BXD69 m 6.854 6.3334851578 19.6646829209 -5.9566829209
BXD73 m 2.766 6.3334851578 15.5766829209 -10.0446829209
BXD77 m 1.595 6.3334851578 14.4056829209 -11.2156829209
BXD79 m 3.9112 4.0056477251 12.0133872824 -4.1909872824
BXD84 m 7.571 6.3334851578 20.3816829209 -5.2396829209
BXD87 m 2.941 6.3334851578 15.7516829209 -9.8696829209
BXD89 m 2.5555 4.4784503036 11.614020765 -6.503020765




  GWAS USING LINEAR MIXED MODELS