Project measure / variable:   Schoonjans1   TUDCA_plasma_t30_HFD

ID, description, units MPD:112713   TUDCA_plasma_t30_HFD   plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means35.149   ng/mL
Median of the strain means33.651   ng/mL
SD of the strain means± 24.49
Coefficient of variation (CV)0.6968
Min–max range of strain means5.2902   –   110.6   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 93337.1678 2666.7762 9.6603 < 0.0001
Residuals 122 33678.593 276.054


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 12.043 4.9552   5 2.216 0.4115 7.378, 17.719 -0.94
BXD100 m 16.876 10.06   9 3.3534 0.5961 2.026, 34.328 -0.75
BXD11 m 40.823 24.69   3 14.255 0.6048 13.054, 60.3 0.23
BXD12 m 86.61 67.08   4 33.538 0.7745 25.438, 178.5 2.1
BXD27 m 26.526 16.865   5 7.5422 0.6358 11.992, 51.33 -0.35
BXD32 m 13.737 8.0458   4 4.0229 0.5857 6.674, 25.12 -0.87
BXD34 m 30.684 9.2087   4 4.6044 0.3001 21.146, 39.292 -0.18
BXD39 m 22.188 13.891   3 8.0201 0.6261 11.2, 37.802 -0.53
BXD40 m 93.44 21.223   4 10.611 0.2271 77.39, 124.6 2.38
BXD43 m 17.239 4.1454   5 1.8539 0.2405 13.468, 23.664 -0.73
BXD45 m 110.6 29.287   5 13.098 0.2648 68.17, 138.2 3.08
BXD48 m 42.043 6.3947   5 2.8598 0.1521 37.576, 52.51 0.28
BXD48a m 73.09 13.839   4 6.9193 0.1893 59.77, 92.33 1.55
BXD49 m 62.36 8.8868   5 3.9743 0.1425 50.39, 75.45 1.11
BXD51 m 35.066 4.523   3 2.6114 0.129 29.964, 38.584 0.0
BXD53 m 38.288 6.7043   5 2.9982 0.1751 30.904, 48.804 0.13
BXD55 m 32.236 5.3485   5 2.3919 0.1659 24.592, 38.408 -0.12
BXD6 m 27.032 15.242   5 6.8165 0.5639 13.882, 49.337 -0.33
BXD62 m 38.472 8.9419   4 4.471 0.2324 25.684, 45.99 0.14
BXD63 m 10.768 1.6056   5 0.71803 0.1491 9.29, 13.17 -1.0
BXD64 m 14.845 6.7516   5 3.0194 0.4548 7.644, 24.054 -0.83
BXD66 m 23.606 1.2844   3 0.74157 0.0544 22.65, 25.066 -0.47
BXD67 m 5.2902 1.9455   5 0.87006 0.3678 3.892, 8.15 -1.22
BXD69 m 35.513 15.305   4 7.6527 0.431 19.74, 50.52 0.01
BXD73 m 9.156 4.9084   3 2.8339 0.5361 5.964, 14.808 -1.06
BXD75 m 39.531 16.758   4 8.3791 0.4239 25.492, 60.64 0.18
BXD77 m 15.991 3.9393   5 1.7617 0.2463 11.832, 22.226 -0.78
BXD79 m 22.133 13.45   5 6.0152 0.6077 13.212, 45.984 -0.53
BXD8 m 35.327 15.895   3 9.1772 0.45 17.71, 48.596 0.01
BXD81 m 36.639 14.474   5 6.473 0.395 18.922, 55.43 0.06
BXD84 m 36.938 32.464   5 14.518 0.8789 17.195, 93.18 0.07
BXD87 m 15.351 4.0407   4 2.0203 0.2632 12.91, 21.356 -0.81
BXD89 m 42.197 5.9964   5 2.6816 0.1421 36.41, 52.32 0.29
BXD90 m 42.176 8.8041   4 4.402 0.2087 32.868, 50.01 0.29
C57BL/6J m 54.57 4.1051   3 2.3701 0.0752 49.828, 57.06 0.79
DBA/2J m 5.9644 5.6792   3 3.2789 0.9522 2.6412, 12.522 -1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 12.0428 7.430397585 26.7520141564 -2.6664141564
BXD100 m 16.8764444444 5.5382913666 27.8400453609 5.912843528
BXD11 m 40.8226666667 9.5926020341 59.8121804878 21.8331528455
BXD12 m 86.6095 8.30743705 103.0549013747 70.1640986253
BXD27 m 26.5256 7.430397585 41.2348141564 11.8163858436
BXD32 m 13.7365 8.30743705 30.1819013747 -2.7089013747
BXD34 m 30.684 8.30743705 47.1294013747 14.2385986253
BXD39 m 22.188 9.5926020341 41.1775138212 3.1984861788
BXD40 m 93.4425 8.30743705 109.8879013747 76.9970986253
BXD43 m 17.2388 7.430397585 31.9480141564 2.5295858436
BXD45 m 110.596 7.430397585 125.3052141564 95.8867858436
BXD48 m 42.0428 7.430397585 56.7520141564 27.3335858436
BXD48a m 73.0925 8.30743705 89.5379013747 56.6470986253
BXD49 m 62.358 7.430397585 77.0672141564 47.6487858436
BXD51 m 35.066 9.5926020341 54.0555138212 16.0764861788
BXD53 m 38.2876 7.430397585 52.9968141564 23.5783858436
BXD55 m 32.2364 7.430397585 46.9456141564 17.5271858436
BXD6 m 27.0322 7.430397585 41.7414141564 12.3229858436
BXD62 m 38.4715 8.30743705 54.9169013747 22.0260986253
BXD63 m 10.7676 7.430397585 25.4768141564 -3.9416141564
BXD64 m 14.8448 7.430397585 29.5540141564 0.1355858436
BXD66 m 23.606 9.5926020341 42.5955138212 4.6164861788
BXD67 m 5.2902 7.430397585 19.9994141564 -9.4190141564
BXD69 m 35.513 8.30743705 51.9584013747 19.0675986253
BXD73 m 9.156 9.5926020341 28.1455138212 -9.8335138212
BXD75 m 39.531 8.30743705 55.9764013747 23.0855986253
BXD77 m 15.9908 7.430397585 30.7000141564 1.2815858436
BXD79 m 22.1328 7.430397585 36.8420141564 7.4235858436
BXD8 m 35.3266666667 9.5926020341 54.3161804878 16.3371528455
BXD81 m 36.6388 7.430397585 51.3480141564 21.9295858436
BXD84 m 36.9378 7.430397585 51.6470141564 22.2285858436
BXD87 m 15.351 8.30743705 31.7964013747 -1.0944013747
BXD89 m 42.1968 7.430397585 56.9060141564 27.4875858436
BXD90 m 42.176 8.30743705 58.6214013747 25.7305986253
C57BL/6J m 54.566 9.5926020341 73.5555138212 35.5764861788
DBA/2J m 5.9644 9.5926020341 24.9539138212 -13.0251138212




  GWAS USING LINEAR MIXED MODELS