Project measure / variable:   Schoonjans1   TUDCA_plasma_t30_CD

ID, description, units MPD:112712   TUDCA_plasma_t30_CD   plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means12.237   ng/mL
Median of the strain means9.4604   ng/mL
SD of the strain means± 9.3138
Coefficient of variation (CV)0.7611
Min–max range of strain means1.568   –   34.748   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 12818.8475 366.2528 10.3186 < 0.0001
Residuals 124 4401.316 35.4945


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 2.2773 0.37536   5 0.16787 0.1648 1.6687, 2.552 -1.07
BXD100 m 14.784 3.6359   5 1.626 0.2459 10.628, 20.348 0.27
BXD11 m 5.6185 3.7581   4 1.879 0.6689 2.51, 10.574 -0.71
BXD12 m 34.748 12.247   3 7.0706 0.3524 27.29, 48.882 2.42
BXD27 m 1.568 0.64845   3 0.37438 0.4136 1.11, 2.31 -1.15
BXD32 m 7.1696 2.6617   5 1.1904 0.3713 4.036, 10.164 -0.54
BXD34 m 4.2276 1.3998   5 0.62601 0.3311 2.32, 5.548 -0.86
BXD39 m 9.7007 5.4616   3 3.1533 0.563 3.95, 14.818 -0.27
BXD40 m 26.134 8.032   4 4.016 0.3073 14.556, 33.134 1.49
BXD43 m 4.1063 3.7267   7 1.4086 0.9076 0.822, 11.12 -0.87
BXD45 m 32.733 12.568   4 6.2842 0.384 21.884, 50.86 2.2
BXD48 m 16.022 4.5401   5 2.0304 0.2834 11.196, 22.202 0.41
BXD48a m 15.513 12.589   4 6.2943 0.8115 6.35, 34.056 0.35
BXD49 m 26.289 8.0518   5 3.6009 0.3063 16.916, 35.582 1.51
BXD51 m 14.54 6.832   5 3.0554 0.4699 7.694, 22.606 0.25
BXD53 m 12.911 4.0241   4 2.012 0.3117 9.752, 18.406 0.07
BXD55 m 7.4912 1.9877   5 0.8889 0.2653 4.32, 9.788 -0.51
BXD6 m 14.628 9.582   5 4.2852 0.655 5.092, 26.45 0.26
BXD62 m 21.893 5.6581   5 2.5304 0.2584 16.388, 30.496 1.04
BXD63 m 4.464 1.8281   4 0.91406 0.4095 2.456, 6.382 -0.83
BXD64 m 9.22 6.7958   5 3.0392 0.7371 4.656, 20.806 -0.32
BXD66 m 3.042 0.86349   3 0.49854 0.2839 2.504, 4.038 -0.99
BXD67 m 3.36 1.6759   4 0.83795 0.4988 1.428, 5.512 -0.95
BXD69 m 5.246 1.3047   5 0.58346 0.2487 4.264, 7.476 -0.75
BXD73 m 5.38 2.7757   3 1.6026 0.5159 3.704, 8.584 -0.74
BXD75 m 5.6887 1.5996   3 0.92354 0.2812 4.262, 7.418 -0.7
BXD77 m 4.3776 2.035   5 0.91008 0.4649 2.718, 7.908 -0.84
BXD79 m 17.394 10.933   5 4.8892 0.6285 5.496, 32.128 0.55
BXD8 m 10.682 5.234   5 2.3407 0.49 5.018, 17.794 -0.17
BXD81 m 16.739 9.7398   3 5.6233 0.5819 9.862, 27.884 0.48
BXD84 m 22.462 7.1815   5 3.2117 0.3197 14.006, 31.662 1.1
BXD87 m 5.5972 1.9751   5 0.88331 0.3529 3.958, 9.028 -0.71
BXD89 m 3.3668 1.2495   5 0.55877 0.3711 2.064, 5.288 -0.95
BXD90 m 13.586 5.9369   5 2.6551 0.437 7.69, 22.878 0.14
C57BL/6J m 31.887 5.9013   5 2.6391 0.1851 24.562, 39.822 2.11
DBA/2J m 5.697 4.4761   4 2.2381 0.7857 1.022, 11.798 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 2.27734 2.6643755056 7.5508854615 -2.9962054615
BXD100 m 14.784 2.6643755056 20.0575454615 9.5104545385
BXD11 m 5.6185 2.9788623741 11.5145030672 -0.2775030672
BXD12 m 34.748 3.4396939871 41.5561179159 27.9398820841
BXD27 m 1.568 3.4396939871 8.3761179159 -5.2401179159
BXD32 m 7.1696 2.6643755056 12.4431454615 1.8960545385
BXD34 m 4.2276 2.6643755056 9.5011454615 -1.0459454615
BXD39 m 9.7006666667 3.4396939871 16.5087845826 2.8925487507
BXD40 m 26.134 2.9788623741 32.0300030672 20.2379969328
BXD43 m 4.1062857143 2.2518082948 8.5632450986 -0.35067367
BXD45 m 32.733 2.9788623741 38.6290030672 26.8369969328
BXD48 m 16.022 2.6643755056 21.2955454615 10.7484545385
BXD48a m 15.513 2.9788623741 21.4090030672 9.6169969328
BXD49 m 26.2892 2.6643755056 31.5627454615 21.0156545385
BXD51 m 14.54 2.6643755056 19.8135454615 9.2664545385
BXD53 m 12.9105 2.9788623741 18.8065030672 7.0144969328
BXD55 m 7.4912 2.6643755056 12.7647454615 2.2176545385
BXD6 m 14.628 2.6643755056 19.9015454615 9.3544545385
BXD62 m 21.8932 2.6643755056 27.1667454615 16.6196545385
BXD63 m 4.464 2.9788623741 10.3600030672 -1.4320030672
BXD64 m 9.22 2.6643755056 14.4935454615 3.9464545385
BXD66 m 3.042 3.4396939871 9.8501179159 -3.7661179159
BXD67 m 3.36 2.9788623741 9.2560030672 -2.5360030672
BXD69 m 5.246 2.6643755056 10.5195454615 -0.0275454615
BXD73 m 5.38 3.4396939871 12.1881179159 -1.4281179159
BXD75 m 5.6886666667 3.4396939871 12.4967845826 -1.1194512493
BXD77 m 4.3776 2.6643755056 9.6511454615 -0.8959454615
BXD79 m 17.3936 2.6643755056 22.6671454615 12.1200545385
BXD8 m 10.6816 2.6643755056 15.9551454615 5.4080545385
BXD81 m 16.7386666667 3.4396939871 23.5467845826 9.9305487507
BXD84 m 22.462 2.6643755056 27.7355454615 17.1884545385
BXD87 m 5.5972 2.6643755056 10.8707454615 0.3236545385
BXD89 m 3.3668 2.6643755056 8.6403454615 -1.9067454615
BXD90 m 13.5856 2.6643755056 18.8591454615 8.3120545385
C57BL/6J m 31.8868 2.6643755056 37.1603454615 26.6132545385
DBA/2J m 5.697 2.9788623741 11.5930030672 -0.1990030672




  GWAS USING LINEAR MIXED MODELS