Project measure / variable:   Schoonjans1   THDCA_plasma_t30_CD

ID, description, units MPD:112710   THDCA_plasma_t30_CD   plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means18.901   ng/mL
Median of the strain means13.736   ng/mL
SD of the strain means± 16.489
Coefficient of variation (CV)0.8724
Min–max range of strain means0.11133   –   66.52   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 37269.9277 1064.8551 7.8719 < 0.0001
Residuals 127 17179.685 135.2731


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 5.083 1.9957   5 0.89252 0.3926 2.6969, 7.636 -0.84
BXD100 m 11.264 3.9051   5 1.7464 0.3467 6.34, 15.3 -0.46
BXD11 m 3.1205 3.1024   4 1.5512 0.9942 0.416, 7.228 -0.96
BXD12 m 57.23 20.68   3 11.94 0.3613 34.326, 74.53 2.32
BXD27 m 6.2765 3.2085   4 1.6043 0.5112 3.514, 10.79 -0.77
BXD32 m 18.738 9.7844   5 4.3757 0.5222 8.776, 34.852 -0.01
BXD34 m 13.785 9.5555   5 4.2734 0.6932 4.412, 26.036 -0.31
BXD39 m 13.687 6.7411   3 3.892 0.4925 7.046, 20.524 -0.32
BXD40 m 66.52 11.049   4 5.5245 0.1661 56.8, 82.38 2.89
BXD43 m 4.1241 3.7468   7 1.4162 0.9085 0.64, 10.224 -0.9
BXD45 m 51.97 16.118   4 8.0589 0.3101 37.578, 67.73 2.01
BXD48 m 33.394 21.002   5 9.3922 0.6289 16.756, 69.24 0.88
BXD48a m 6.7935 5.9869   4 2.9934 0.8813 2.342, 15.584 -0.73
BXD49 m 28.303 12.881   5 5.7606 0.4551 10.858, 44.45 0.57
BXD51 m 10.466 5.7184   5 2.5574 0.5464 1.296, 16.63 -0.51
BXD53 m 23.238 10.668   4 5.334 0.4591 16.912, 39.094 0.26
BXD55 m 10.789 6.2074   5 2.776 0.5753 4.196, 18.738 -0.49
BXD6 m 0.11133 0.05205   3 0.03005 0.4675 0.058, 0.162 -1.14
BXD62 m 7.6328 2.3267   5 1.0405 0.3048 5.042, 10.81 -0.68
BXD63 m 20.081 17.842   4 8.9212 0.8885 6.41, 44.734 0.07
BXD64 m 5.566 3.6883   5 1.6495 0.6627 1.84, 10.678 -0.81
BXD66 m 2.1552 1.7934   5 0.80205 0.8321 0.734, 5.242 -1.02
BXD67 m 0.828 0.4998   4 0.2499 0.6036 0.27, 1.486 -1.1
BXD69 m 18.155 14.971   5 6.6952 0.8246 5.804, 39.976 -0.05
BXD73 m 45.676 18.133   3 10.469 0.397 26.188, 62.05 1.62
BXD75 m 25.949 19.29   5 8.6268 0.7434 9.584, 47.914 0.43
BXD77 m 12.056 4.2534   5 1.9022 0.3528 6.144, 17.188 -0.42
BXD79 m 21.593 22.635   5 10.123 1.0483 6.026, 60.43 0.16
BXD8 m 25.432 14.577   5 6.519 0.5732 8.318, 46.634 0.4
BXD81 m 41.066 26.752   3 15.445 0.6514 11.556, 63.73 1.34
BXD84 m 21.548 11.641   5 5.2062 0.5403 13.0, 39.82 0.16
BXD87 m 24.162 15.623   5 6.9866 0.6466 12.328, 51.27 0.32
BXD89 m 7.866 4.831   5 2.1605 0.6142 3.094, 13.862 -0.67
BXD90 m 6.484 4.2594   5 1.9049 0.6569 2.02, 12.888 -0.75
C57BL/6J m 24.336 13.382   5 5.9848 0.5499 9.62, 44.552 0.33
DBA/2J m 4.9545 4.689   4 2.3445 0.9464 0.152, 11.4 -0.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 5.08298 5.2014057797 15.3756233649 -5.2096633649
BXD100 m 11.2644 5.2014057797 21.5570433649 0.9717566351
BXD11 m 3.1205 5.815348451 14.628025116 -8.387025116
BXD12 m 57.232 6.7149859873 70.5197454468 43.9442545532
BXD27 m 6.2765 5.815348451 17.784025116 -5.231025116
BXD32 m 18.738 5.2014057797 29.0306433649 8.4453566351
BXD34 m 13.7852 5.2014057797 24.0778433649 3.4925566351
BXD39 m 13.6873333333 6.7149859873 26.9750787802 0.3995878865
BXD40 m 66.515 5.815348451 78.022525116 55.007474884
BXD43 m 4.1241428571 4.3959902253 12.8230141894 -4.5747284751
BXD45 m 51.9735 5.815348451 63.481025116 40.465974884
BXD48 m 33.3944 5.2014057797 43.6870433649 23.1017566351
BXD48a m 6.7935 5.815348451 18.301025116 -4.714025116
BXD49 m 28.3028 5.2014057797 38.5954433649 18.0101566351
BXD51 m 10.466 5.2014057797 20.7586433649 0.1733566351
BXD53 m 23.2385 5.815348451 34.746025116 11.730974884
BXD55 m 10.7892 5.2014057797 21.0818433649 0.4965566351
BXD6 m 0.1113333333 6.7149859873 13.3990787802 -13.1764121135
BXD62 m 7.6328 5.2014057797 17.9254433649 -2.6598433649
BXD63 m 20.0805 5.815348451 31.588025116 8.572974884
BXD64 m 5.566 5.2014057797 15.8586433649 -4.7266433649
BXD66 m 2.1552 5.2014057797 12.4478433649 -8.1374433649
BXD67 m 0.828 5.815348451 12.335525116 -10.679525116
BXD69 m 18.1552 5.2014057797 28.4478433649 7.8625566351
BXD73 m 45.676 6.7149859873 58.9637454468 32.3882545532
BXD75 m 25.9492 5.2014057797 36.2418433649 15.6565566351
BXD77 m 12.0556 5.2014057797 22.3482433649 1.7629566351
BXD79 m 21.5928 5.2014057797 31.8854433649 11.3001566351
BXD8 m 25.4324 5.2014057797 35.7250433649 15.1397566351
BXD81 m 41.0663333333 6.7149859873 54.3540787802 27.7785878865
BXD84 m 21.5478 5.2014057797 31.8404433649 11.2551566351
BXD87 m 24.162 5.2014057797 34.4546433649 13.8693566351
BXD89 m 7.866 5.2014057797 18.1586433649 -2.4266433649
BXD90 m 6.484 5.2014057797 16.7766433649 -3.8086433649
C57BL/6J m 24.3364 5.2014057797 34.6290433649 14.0437566351
DBA/2J m 4.9545 5.815348451 16.462025116 -6.553025116




  GWAS USING LINEAR MIXED MODELS