Project measure / variable:   Schoonjans1   TDCA_plasma_t30_HFD

ID, description, units MPD:112709   TDCA_plasma_t30_HFD   plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means36.971   ng/mL
Median of the strain means29.584   ng/mL
SD of the strain means± 26.87
Coefficient of variation (CV)0.7268
Min–max range of strain means8.515   –   114.3   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 101074.3686 2972.7755 4.1103 < 0.0001
Residuals 116 83896.4153 723.245


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 35.047 15.855   5 7.0905 0.4524 14.306, 58.94 -0.07
BXD100 m 18.967 13.975   9 4.6582 0.7368 2.146, 34.792 -0.67
BXD11 m 14.632 0.0   1   0.0 0.0 14.632, 14.632 -0.83
BXD12 m 52.47 27.729   4 13.864 0.5285 13.436, 72.95 0.58
BXD27 m 22.513 14.39   5 6.4356 0.6392 5.516, 41.458 -0.54
BXD32 m 34.543 24.177   4 12.088 0.6999 16.318, 68.01 -0.09
BXD34 m 12.507 6.6478   4 3.3239 0.5315 6.364, 21.756 -0.91
BXD39 m 27.839 35.96   3 20.762 1.2917 3.322, 69.12 -0.34
BXD40 m 30.43 14.379   4 7.1896 0.4725 17.952, 49.364 -0.24
BXD43 m 18.96 8.8244   5 3.9464 0.4654 7.854, 32.012 -0.67
BXD45 m 20.969 15.518   5 6.94 0.74 10.268, 48.0 -0.6
BXD48 m 51.24 23.08   5 10.322 0.4505 14.414, 73.3 0.53
BXD48a m 67.88 31.393   4 15.697 0.4625 45.472, 113.0 1.15
BXD49 m 32.196 14.595   5 6.5269 0.4533 24.492, 58.15 -0.18
BXD51 m 30.076 6.872   3 3.9676 0.2285 25.72, 37.998 -0.26
BXD53 m 30.022 15.8   5 7.0658 0.5263 13.934, 56.07 -0.26
BXD55 m 20.554 8.7635   5 3.9192 0.4264 11.886, 33.87 -0.61
BXD6 m 22.569 18.351   3 10.595 0.8131 8.204, 43.242 -0.54
BXD62 m 23.86 4.555   4 2.2775 0.1909 17.736, 28.632 -0.49
BXD63 m 110.4 32.721   5 14.633 0.2963 74.68, 146.3 2.73
BXD64 m 8.515 5.4578   4 2.7289 0.641 2.926, 14.888 -1.06
BXD66 m 11.019 7.6373   3 4.4094 0.6931 5.796, 19.784 -0.97
BXD67 m 13.683 3.0176   5 1.3495 0.2205 11.04, 18.505 -0.87
BXD69 m 98.15 72.73   4 36.363 0.7409 24.506, 184.4 2.28
BXD73 m 8.974 8.0819   3 4.6661 0.9006 1.248, 17.37 -1.04
BXD75 m 63.7 34.84   4 17.42 0.547 37.574, 113.0 0.99
BXD77 m 27.515 7.3403   5 3.2827 0.2668 16.312, 35.902 -0.35
BXD79 m 41.549 57.38   5 25.661 1.381 13.138, 143.9 0.17
BXD8 m 30.825 5.1774   2   3.661 0.168 27.164, 34.486 -0.23
BXD81 m 58.07 18.301   5 8.1843 0.3151 36.686, 81.84 0.79
BXD84 m 63.58 56.02   5 25.055 0.8811 22.164, 154.1 0.99
BXD87 m 29.145 16.068   4 8.0341 0.5513 13.432, 46.948 -0.29
BXD89 m 46.622 47.406   5 21.201 1.0168 18.584, 130.6 0.36
BXD90 m 20.113 16.963   4 8.4815 0.8434 4.6176, 43.684 -0.63
C57BL/6J m 114.3 27.217   3 15.714 0.2381 82.87, 130.6 2.88
DBA/2J m 17.524 9.253   3 5.3422 0.528 7.472, 25.686 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 35.047 12.0270109275 58.8680105748 11.2259894252
BXD100 m 18.9666666667 8.9644046667 36.721799646 1.2115336873
BXD12 m 52.469 13.446607 79.1016994691 25.836300531
BXD27 m 22.5128 12.0270109275 46.3338105748 -1.3082105748
BXD32 m 34.543 13.446607 61.175699469 7.9103005309
BXD34 m 12.5075 13.446607 39.1401994691 -14.1251994691
BXD39 m 27.8386666667 15.5268043423 58.5914590821 -2.9141257487
BXD40 m 30.4305 13.446607 57.063199469 3.7978005309
BXD43 m 18.9596 12.0270109275 42.7806105748 -4.8614105748
BXD45 m 20.9692 12.0270109275 44.7902105748 -2.8518105748
BXD48 m 51.2364 12.0270109275 75.0574105748 27.4153894252
BXD48a m 67.88 13.446607 94.5126994691 41.247300531
BXD49 m 32.1964 12.0270109275 56.0174105748 8.3753894252
BXD51 m 30.076 15.5268043423 60.8287924154 -0.6767924154
BXD53 m 30.0224 12.0270109275 53.8434105748 6.2013894252
BXD55 m 20.5536 12.0270109275 44.3746105748 -3.2674105748
BXD6 m 22.5686666667 15.5268043423 53.3214590821 -8.1841257487
BXD62 m 23.8595 13.446607 50.4921994691 -2.7731994691
BXD63 m 110.416 12.0270109275 134.2370105748 86.5949894252
BXD64 m 8.515 13.446607 35.1476994691 -18.1176994691
BXD66 m 11.0186666667 15.5268043423 41.7714590821 -19.7341257487
BXD67 m 13.683 12.0270109275 37.5040105748 -10.1380105748
BXD69 m 98.154 13.446607 124.786699469 71.5213005309
BXD73 m 8.974 15.5268043423 39.7267924154 -21.7787924154
BXD75 m 63.6965 13.446607 90.3291994691 37.0638005309
BXD77 m 27.5148 12.0270109275 51.3358105748 3.6937894252
BXD79 m 41.5492 12.0270109275 65.3702105748 17.7281894252
BXD8 m 30.825 19.0163739873 68.4893247917 -6.8393247917
BXD81 m 58.0708 12.0270109275 81.8918105748 34.2497894252
BXD84 m 63.585 12.0270109275 87.4060105748 39.7639894252
BXD87 m 29.1455 13.446607 55.7781994691 2.5128005309
BXD89 m 46.6224 12.0270109275 70.4434105748 22.8013894252
BXD90 m 20.1129 13.446607 46.7455994691 -6.519799469
C57BL/6J m 114.29 15.5268043423 145.0427924154 83.5372075846
DBA/2J m 17.5243333333 15.5268043423 48.2771257487 -13.2284590821




  GWAS USING LINEAR MIXED MODELS