Project measure / variable:   Schoonjans1   TDCA_plasma_t30_CD

ID, description, units MPD:112708   TDCA_plasma_t30_CD   plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means44.048   ng/mL
Median of the strain means32.029   ng/mL
SD of the strain means± 36.049
Coefficient of variation (CV)0.8184
Min–max range of strain means1.564   –   148.3   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 207666.8877 6107.8496 5.0219 < 0.0001
Residuals 123 149596.711 1216.2334


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 52.41 21.093   5 9.4329 0.4024 23.484, 72.09 0.23
BXD100 m 22.81 5.2084   5 2.3293 0.2283 15.986, 28.906 -0.59
BXD11 m 38.375 31.967   4 15.983 0.833 10.026, 84.23 -0.16
BXD12 m 18.893 6.4922   3 3.7483 0.3436 12.012, 24.91 -0.7
BXD27 m 24.85 8.8361   4 4.418 0.3556 17.284, 34.772 -0.53
BXD32 m 62.13 33.183   5 14.84 0.5341 35.032, 105.9 0.5
BXD34 m 6.246 2.2712   5 1.0157 0.3636 3.56, 9.292 -1.05
BXD39 m 19.254 8.655   3 4.997 0.4495 10.608, 27.918 -0.69
BXD40 m 30.955 22.863   4 11.431 0.7386 11.12, 63.74 -0.36
BXD43 m 10.473 8.5008   7 3.213 0.8117 1.892, 24.24 -0.93
BXD45 m 85.69 31.05   4 15.525 0.3624 56.3, 113.7 1.16
BXD48 m 101.4 31.04   5 13.882 0.3062 61.2, 139.4 1.59
BXD48a m 22.21 17.733   4 8.8667 0.7984 11.24, 48.666 -0.61
BXD49 m 61.29 30.139   5 13.478 0.4918 20.306, 93.71 0.48
BXD51 m 22.233 12.527   5 5.6021 0.5634 13.034, 42.326 -0.61
BXD53 m 27.512 12.531   4 6.2654 0.4555 16.99, 45.37 -0.46
BXD55 m 58.87 30.697   5 13.728 0.5214 11.822, 88.85 0.41
BXD6 m 1.564 0.0   1   0.0 0.0 1.564, 1.564 -1.18
BXD62 m 60.64 21.241   5 9.4993 0.3503 33.152, 79.25 0.46
BXD63 m 63.14 33.768   4 16.884 0.5348 27.564, 104.9 0.53
BXD64 m 10.271 9.4079   4 4.7039 0.916 2.15, 23.448 -0.94
BXD66 m 9.7336 3.9199   5 1.753 0.4027 3.716, 14.426 -0.95
BXD67 m 3.9493 1.8033   3 1.0411 0.4566 1.874, 5.134 -1.11
BXD69 m 33.104 28.219   5 12.62 0.8524 12.314, 82.57 -0.3
BXD73 m 74.7 41.254   3 23.818 0.5523 29.486, 110.3 0.85
BXD75 m 81.29 35.7   5 15.965 0.4392 38.418, 122.3 1.03
BXD77 m 12.517 4.0881   5 1.8283 0.3266 8.15, 18.856 -0.87
BXD79 m 114.3 137.3   5 61.42 1.2015 8.98, 351.5 1.95
BXD8 m 29.339 19.107   5 8.5451 0.6513 18.13, 63.19 -0.41
BXD81 m 38.46 23.35   3 13.481 0.6071 12.992, 58.86 -0.15
BXD84 m 50.24 23.445   5 10.485 0.4666 25.192, 83.0 0.17
BXD87 m 120.7 41.601   5 18.604 0.3447 84.39, 192.1 2.13
BXD89 m 23.468 9.4628   5 4.2319 0.4032 13.748, 39.212 -0.57
BXD90 m 9.204 4.272   5 1.9105 0.4641 5.846, 16.394 -0.97
C57BL/6J m 148.3 56.01   5 25.046 0.3775 103.8, 244.6 2.89
DBA/2J m 35.191 37.19   4 18.595 1.0568 6.702, 89.9 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 52.4112 15.5963676694 83.2832535118 21.5391464882
BXD100 m 22.8096 15.5963676694 53.6816535118 -8.0624535118
BXD11 m 38.375 17.4372691554 72.8910051287 3.8589948713
BXD12 m 18.8926666667 20.1348240817 58.7483163714 -20.9629830381
BXD27 m 24.8505 17.4372691554 59.3665051287 -9.6655051287
BXD32 m 62.1336 15.5963676694 93.0056535118 31.2615464882
BXD34 m 6.246 15.5963676694 37.1180535118 -24.6260535118
BXD39 m 19.254 20.1348240817 59.1096497048 -20.6016497048
BXD40 m 30.955 17.4372691554 65.4710051287 -3.5610051287
BXD43 m 10.4731428571 13.1813364941 36.5647902348 -15.6185045205
BXD45 m 85.685 17.4372691554 120.2010051287 51.1689948713
BXD48 m 101.382 15.5963676694 132.2540535118 70.5099464882
BXD48a m 22.21 17.4372691554 56.7260051287 -12.3060051287
BXD49 m 61.288 15.5963676694 92.1600535118 30.4159464882
BXD51 m 22.2328 15.5963676694 53.1048535118 -8.6392535118
BXD53 m 27.5125 17.4372691554 62.0285051287 -7.0035051287
BXD55 m 58.8692 15.5963676694 89.7412535118 27.9971464882
BXD62 m 60.6448 15.5963676694 91.5168535118 29.7727464882
BXD63 m 63.1355 17.4372691554 97.6515051287 28.6194948713
BXD64 m 10.271 17.4372691554 44.7870051287 -24.2450051287
BXD66 m 9.7336 15.5963676694 40.6056535118 -21.1384535118
BXD67 m 3.9493333333 20.1348240817 43.8049830381 -35.9063163714
BXD69 m 33.1036 15.5963676694 63.9756535118 2.2315464882
BXD73 m 74.6953333333 20.1348240817 114.5509830381 34.8396836286
BXD75 m 81.2908 15.5963676694 112.1628535118 50.4187464882
BXD77 m 12.5168 15.5963676694 43.3888535118 -18.3552535118
BXD79 m 114.3056 15.5963676694 145.1776535118 83.4335464882
BXD8 m 29.3388 15.5963676694 60.2108535118 -1.5332535118
BXD81 m 38.46 20.1348240817 78.3156497048 -1.3956497048
BXD84 m 50.2436 15.5963676694 81.1156535118 19.3715464882
BXD87 m 120.678 15.5963676694 151.5500535118 89.8059464882
BXD89 m 23.4676 15.5963676694 54.3396535118 -7.4044535118
BXD90 m 9.204 15.5963676694 40.0760535118 -21.6680535118
C57BL/6J m 148.34 15.5963676694 179.2120535118 117.4679464882
DBA/2J m 35.1905 17.4372691554 69.7065051287 0.6744948713




  GWAS USING LINEAR MIXED MODELS