Project measure / variable:   Schoonjans1   TCA_plasma_t30_CD

ID, description, units MPD:112704   TCA_plasma_t30_CD   plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means191.6   ng/mL
Median of the strain means166.8   ng/mL
SD of the strain means± 100.5
Coefficient of variation (CV)0.5247
Min–max range of strain means52.31   –   481.7   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1626951.6205 46484.332 2.6055 < 0.0001
Residuals 130 2319334.5493 17841.035


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 157.6 25.513   5 11.41 0.1619 122.2, 184.8 -0.34
BXD100 m 225.7 60.9   5 27.234 0.2698 178.6, 328.1 0.34
BXD11 m 129.6 98.34   4 49.172 0.7591 43.78, 245.4 -0.62
BXD12 m 155.1 51.41   3 29.681 0.3314 113.8, 212.7 -0.36
BXD27 m 172.8 94.82   4 47.41 0.5488 67.66, 292.3 -0.19
BXD32 m 263.1 149.1   5 66.67 0.5667 134.7, 498.5 0.71
BXD34 m 164.9 65.25   5 29.181 0.3957 93.81, 232.3 -0.27
BXD39 m 409.6 91.24   3 52.68 0.2227 316.9, 499.3 2.17
BXD40 m 254.9 47.364   4 23.682 0.1858 212.6, 317.0 0.63
BXD43 m 123.2 108.6   7 41.058 0.8821 24.36, 303.4 -0.68
BXD45 m 222.9 87.39   4 43.696 0.3921 139.7, 339.5 0.31
BXD48 m 129.5 51.53   5 23.047 0.398 83.16, 208.8 -0.62
BXD48a m 62.67 58.2   4 29.099 0.9287 21.676, 148.7 -1.28
BXD49 m 182.0 81.14   5 36.285 0.4459 64.67, 271.9 -0.1
BXD51 m 386.1 204.0   5 91.24 0.5284 85.8, 601.8 1.94
BXD53 m 193.7 187.7   4 93.86 0.9691 85.28, 474.8 0.02
BXD55 m 138.8 58.52   5 26.171 0.4216 53.11, 216.4 -0.53
BXD6 m 245.9 168.5   5 75.36 0.6853 78.66, 490.8 0.54
BXD62 m 385.7 138.6   5 62.0 0.3594 215.5, 552.2 1.93
BXD63 m 172.9 139.4   4 69.72 0.8066 56.1, 363.9 -0.19
BXD64 m 135.4 105.2   5 47.042 0.7771 66.73, 312.9 -0.56
BXD66 m 112.8 36.588   5 16.362 0.3245 63.62, 151.4 -0.78
BXD67 m 86.06 40.723   4 20.361 0.4732 51.92, 138.6 -1.05
BXD69 m 124.1 83.37   5 37.285 0.672 50.33, 243.4 -0.67
BXD73 m 168.7 128.6   4 64.28 0.7619 0.936, 312.9 -0.23
BXD75 m 238.4 155.9   5 69.72 0.6538 88.14, 471.0 0.47
BXD77 m 103.1 27.19   5 12.16 0.2636 65.94, 136.4 -0.88
BXD79 m 481.7 498.5   5 223.0 1.035 100.1, 1318.0 2.89
BXD8 m 287.8 120.9   5 54.08 0.4201 107.2, 408.6 0.96
BXD81 m 116.0 49.609   3 28.642 0.4275 60.62, 156.3 -0.75
BXD84 m 134.6 73.6   5 32.916 0.5469 80.19, 258.1 -0.57
BXD87 m 230.4 116.5   5 52.11 0.5058 164.0, 435.9 0.39
BXD89 m 71.28 31.805   5 14.223 0.4462 32.618, 109.7 -1.2
BXD90 m 52.31 24.862   5 11.118 0.4753 26.414, 85.68 -1.39
C57BL/6J m 249.0 97.83   5 43.751 0.393 137.6, 405.7 0.57
DBA/2J m 128.5 91.75   4 45.875 0.7138 25.774, 249.1 -0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 157.58 59.7344707761 275.7575065131 39.4024934869
BXD100 m 225.7 59.7344707761 343.8775065131 107.5224934869
BXD11 m 129.55 66.7851686276 261.6764689874 -2.5764689874
BXD12 m 155.1333333333 77.1168701701 307.6998382072 2.5668284594
BXD27 m 172.79 66.7851686276 304.9164689874 40.6635310126
BXD32 m 263.08 59.7344707761 381.2575065131 144.9024934869
BXD34 m 164.922 59.7344707761 283.0995065131 46.7444934869
BXD39 m 409.6333333333 77.1168701701 562.1998382072 257.0668284594
BXD40 m 254.875 66.7851686276 387.0014689874 122.7485310126
BXD43 m 123.1545714286 50.4848421304 223.0327938714 23.2763489858
BXD45 m 222.9 66.7851686276 355.0264689874 90.7735310126
BXD48 m 129.49 59.7344707761 247.6675065131 11.3124934869
BXD48a m 62.6685 66.7851686276 194.7949689874 -69.4579689874
BXD49 m 181.974 59.7344707761 300.1515065131 63.7964934869
BXD51 m 386.1 59.7344707761 504.2775065131 267.9224934869
BXD53 m 193.695 66.7851686276 325.8214689874 61.5685310126
BXD55 m 138.802 59.7344707761 256.9795065131 20.6244934869
BXD6 m 245.912 59.7344707761 364.0895065131 127.7344934869
BXD62 m 385.72 59.7344707761 503.8975065131 267.5424934869
BXD63 m 172.8725 66.7851686276 304.9989689874 40.7460310126
BXD64 m 135.368 59.7344707761 253.5455065131 17.1904934869
BXD66 m 112.758 59.7344707761 230.9355065131 -5.4195065131
BXD67 m 86.0625 66.7851686276 218.1889689874 -46.0639689874
BXD69 m 124.064 59.7344707761 242.2415065131 5.8864934869
BXD73 m 168.734 66.7851686276 300.8604689874 36.6075310126
BXD75 m 238.448 59.7344707761 356.6255065131 120.2704934869
BXD77 m 103.132 59.7344707761 221.3095065131 -15.0455065131
BXD79 m 481.7 59.7344707761 599.8775065131 363.5224934869
BXD8 m 287.82 59.7344707761 405.9975065131 169.6424934869
BXD81 m 116.04 77.1168701701 268.6065048739 -36.5265048739
BXD84 m 134.59 59.7344707761 252.7675065131 16.4124934869
BXD87 m 230.4 59.7344707761 348.5775065131 112.2224934869
BXD89 m 71.2772 59.7344707761 189.4547065131 -46.9003065131
BXD90 m 52.31 59.7344707761 170.4875065131 -65.8675065131
C57BL/6J m 248.96 59.7344707761 367.1375065131 130.7824934869
DBA/2J m 128.5435 66.7851686276 260.6699689874 -3.5829689874




  GWAS USING LINEAR MIXED MODELS