Project measure / variable:   Schoonjans1   TbMCA_plasma_t30_HFD

ID, description, units MPD:112703   TbMCA_plasma_t30_HFD   plasma bile acid tauro-β-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-β-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means216.4   ng/mL
Median of the strain means173.0   ng/mL
SD of the strain means± 133.9
Coefficient of variation (CV)0.6185
Min–max range of strain means49.647   –   617.2   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 2630528.8352 75157.9667 2.1386 0.0012
Residuals 122 4287443.893 35142.9827


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 111.4 71.24   5 31.861 0.6395 42.756, 219.7 -0.78
BXD100 m 145.0 96.08   9 32.025 0.6627 27.212, 301.5 -0.53
BXD11 m 318.9 113.4   3 65.47 0.3555 211.4, 437.4 0.77
BXD12 m 617.2 900.3   4 450.1 1.4586 79.04, 1961.0 2.99
BXD27 m 242.7 158.2   5 70.75 0.652 90.97, 475.4 0.2
BXD32 m 100.1 78.79   4 39.396 0.7872 31.224, 212.4 -0.87
BXD34 m 221.1 112.8   4 56.41 0.5103 138.9, 381.2 0.04
BXD39 m 146.0 93.45   3 53.96 0.6403 38.064, 201.7 -0.53
BXD40 m 326.4 92.51   4 46.254 0.2834 227.4, 444.4 0.82
BXD43 m 214.7 37.734   5 16.875 0.1758 174.1, 266.7 -0.01
BXD45 m 282.2 56.87   5 25.432 0.2015 218.0, 350.0 0.49
BXD48 m 92.27 31.111   5 13.913 0.3372 57.72, 139.4 -0.93
BXD48a m 238.3 55.24   4 27.622 0.2318 164.6, 296.1 0.16
BXD49 m 330.0 86.01   5 38.466 0.2606 243.5, 446.8 0.85
BXD51 m 338.4 120.7   3 69.71 0.3568 260.8, 477.5 0.91
BXD53 m 112.9 22.714   5 10.158 0.2012 73.7, 128.3 -0.77
BXD55 m 163.6 31.821   5 14.231 0.1945 116.5, 200.1 -0.39
BXD6 m 498.9 250.6   5 112.1 0.5022 302.9, 896.5 2.11
BXD62 m 296.6 90.38   4 45.189 0.3047 175.1, 369.8 0.6
BXD63 m 108.3 22.182   5 9.9201 0.2048 89.73, 146.2 -0.81
BXD64 m 136.4 27.005   5 12.077 0.1981 99.67, 169.6 -0.6
BXD66 m 82.83 14.691   3 8.4816 0.1774 67.91, 97.28 -1.0
BXD67 m 55.79 35.629   5 15.934 0.6386 22.49, 115.4 -1.2
BXD69 m 256.8 90.06   4 45.03 0.3507 179.9, 386.6 0.3
BXD73 m 104.4 59.46   3 34.33 0.5696 66.21, 172.9 -0.84
BXD75 m 404.1 319.1   4 159.6 0.7897 135.4, 782.9 1.4
BXD77 m 92.32 24.394   5 10.91 0.2642 62.9, 130.4 -0.93
BXD79 m 362.6 295.6   5 132.2 0.8154 158.6, 884.2 1.09
BXD8 m 431.1 231.0   3 133.4 0.5359 170.4, 610.5 1.6
BXD81 m 116.4 71.46   5 31.96 0.6138 46.446, 226.4 -0.75
BXD84 m 243.8 271.3   5 121.3 1.1127 85.1, 726.3 0.2
BXD87 m 118.2 42.251   4 21.126 0.3574 68.97, 170.5 -0.73
BXD89 m 139.9 55.69   5 24.907 0.3982 91.7, 226.8 -0.57
BXD90 m 108.8 35.597   4 17.798 0.3273 74.31, 158.7 -0.8
C57BL/6J m 182.4 90.74   3 52.39 0.4976 100.8, 280.1 -0.25
DBA/2J m 49.647 49.487   3 28.571 0.9968 16.242, 106.5 -1.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 111.4052 83.8367255194 277.368371651 -54.557971651
BXD100 m 144.9695555556 62.4882057575 268.6712000799 21.2679110312
BXD11 m 318.9333333333 108.2327472458 533.1908666294 104.6758000373
BXD12 m 617.21 93.7323086362 802.7624667866 431.6575332134
BXD27 m 242.654 83.8367255194 408.617171651 76.690828349
BXD32 m 100.091 93.7323086362 285.6434667866 -85.4614667866
BXD34 m 221.1 93.7323086362 406.6524667866 35.5475332134
BXD39 m 145.9546666667 108.2327472458 360.2121999627 -68.3028666294
BXD40 m 326.425 93.7323086362 511.9774667866 140.8725332134
BXD43 m 214.68 83.8367255194 380.643171651 48.716828349
BXD45 m 282.2 83.8367255194 448.163171651 116.236828349
BXD48 m 92.272 83.8367255194 258.235171651 -73.691171651
BXD48a m 238.325 93.7323086362 423.8774667866 52.7725332134
BXD49 m 330.04 83.8367255194 496.003171651 164.076828349
BXD51 m 338.4 108.2327472458 552.657533296 124.142466704
BXD53 m 112.9 83.8367255194 278.863171651 -53.063171651
BXD55 m 163.62 83.8367255194 329.583171651 -2.343171651
BXD6 m 498.92 83.8367255194 664.883171651 332.956828349
BXD62 m 296.65 93.7323086362 482.2024667866 111.0975332134
BXD63 m 108.334 83.8367255194 274.297171651 -57.629171651
BXD64 m 136.354 83.8367255194 302.317171651 -29.609171651
BXD66 m 82.83 108.2327472458 297.087533296 -131.427533296
BXD67 m 55.7928 83.8367255194 221.755971651 -110.170371651
BXD69 m 256.8 93.7323086362 442.3524667866 71.2475332134
BXD73 m 104.39 108.2327472458 318.647533296 -109.867533296
BXD75 m 404.125 93.7323086362 589.6774667866 218.5725332134
BXD77 m 92.322 83.8367255194 258.285171651 -73.641171651
BXD79 m 362.56 83.8367255194 528.523171651 196.596828349
BXD8 m 431.0666666667 108.2327472458 645.3241999627 216.8091333706
BXD81 m 116.4352 83.8367255194 282.398371651 -49.527971651
BXD84 m 243.84 83.8367255194 409.803171651 77.876828349
BXD87 m 118.2175 93.7323086362 303.7699667866 -67.3349667866
BXD89 m 139.854 83.8367255194 305.817171651 -26.109171651
BXD90 m 108.7525 93.7323086362 294.3049667866 -76.7999667866
C57BL/6J m 182.3666666667 108.2327472458 396.6241999627 -31.8908666294
DBA/2J m 49.6473333333 108.2327472458 263.9048666294 -164.6101999627




  GWAS USING LINEAR MIXED MODELS