Project measure / variable:   Schoonjans1   TaMCA_plasma_t30_CD

ID, description, units MPD:112700   TaMCA_plasma_t30_CD   plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means43.03   ng/mL
Median of the strain means33.978   ng/mL
SD of the strain means± 24.719
Coefficient of variation (CV)0.5745
Min–max range of strain means10.468   –   106.3   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 91666.8234 2619.0521 3.2684 < 0.0001
Residuals 130 104173.4296 801.3341


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 10.468 2.2473   5 1.005 0.2147 7.2938, 13.044 -1.32
BXD100 m 65.04 28.984   5 12.962 0.4456 43.248, 114.9 0.89
BXD11 m 34.243 33.203   4 16.602 0.9696 8.798, 79.48 -0.36
BXD12 m 104.0 26.527   3 15.315 0.255 73.44, 120.4 2.47
BXD27 m 29.288 10.049   4 5.0246 0.3431 17.84, 38.53 -0.56
BXD32 m 43.475 23.402   5 10.466 0.5383 18.89, 80.73 0.02
BXD34 m 33.712 22.137   5 9.9002 0.6567 12.182, 63.22 -0.38
BXD39 m 51.65 34.786   3 20.084 0.6735 23.392, 90.5 0.35
BXD40 m 76.69 18.865   4 9.4325 0.246 51.07, 95.51 1.36
BXD43 m 20.752 17.308   7 6.5418 0.834 2.922, 53.71 -0.9
BXD45 m 106.3 62.88   4 31.439 0.5917 65.89, 198.8 2.56
BXD48 m 25.912 18.846   5 8.428 0.7273 13.224, 59.24 -0.69
BXD48a m 16.633 13.622   4 6.811 0.819 5.2, 35.442 -1.07
BXD49 m 56.86 18.941   5 8.4706 0.3331 28.66, 78.31 0.56
BXD51 m 73.22 41.295   5 18.468 0.564 14.126, 114.7 1.22
BXD53 m 33.663 22.138   4 11.069 0.6576 17.25, 66.33 -0.38
BXD55 m 39.084 16.96   5 7.5846 0.4339 21.698, 57.02 -0.16
BXD6 m 53.89 48.021   5 21.475 0.8912 15.496, 134.5 0.44
BXD62 m 84.84 39.707   5 17.758 0.468 45.456, 128.1 1.69
BXD63 m 33.416 29.191   4 14.596 0.8736 9.77, 72.99 -0.39
BXD64 m 35.232 31.665   5 14.161 0.8988 10.72, 85.72 -0.32
BXD66 m 22.594 9.1747   5 4.103 0.4061 11.834, 34.204 -0.83
BXD67 m 12.491 4.6965   4 2.3483 0.376 8.152, 19.148 -1.24
BXD69 m 31.062 17.26   5 7.7189 0.5557 15.714, 50.36 -0.48
BXD73 m 38.242 30.982   4 15.491 0.8102 0.036, 66.84 -0.19
BXD75 m 56.09 43.689   5 19.538 0.7789 18.544, 124.9 0.53
BXD77 m 33.155 9.1841   5 4.1072 0.277 18.264, 39.51 -0.4
BXD79 m 63.94 57.8   5 25.85 0.904 12.28, 159.2 0.85
BXD8 m 61.36 26.371   5 11.793 0.4298 20.948, 89.1 0.74
BXD81 m 20.556 9.911   3 5.7221 0.4821 11.296, 31.01 -0.91
BXD84 m 27.306 17.013   5 7.6082 0.623 15.442, 57.37 -0.64
BXD87 m 27.4 22.946   5 10.262 0.8374 12.898, 67.28 -0.63
BXD89 m 19.871 14.05   5 6.2834 0.7071 8.828, 42.732 -0.94
BXD90 m 14.741 8.6973   5 3.8896 0.59 6.954, 27.692 -1.14
C57BL/6J m 67.64 37.183   5 16.629 0.5497 28.05, 128.8 1.0
DBA/2J m 24.256 16.841   4 8.4206 0.6943 5.806, 45.112 -0.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 10.46836 12.65965303 35.5139694943 -14.5772494943
BXD100 m 65.0424 12.65965303 90.0880094943 39.9967905057
BXD11 m 34.243 14.1539223733 62.2448426836 6.2411573164
BXD12 m 104.0466666667 16.3435417847 136.3804094891 71.7129238443
BXD27 m 29.288 14.1539223733 57.2898426836 1.2861573164
BXD32 m 43.4748 12.65965303 68.5204094943 18.4291905057
BXD34 m 33.7116 12.65965303 58.7572094943 8.6659905057
BXD39 m 51.6473333333 16.3435417847 83.9810761557 19.3135905109
BXD40 m 76.6875 14.1539223733 104.6893426836 48.6856573164
BXD43 m 20.7522857143 10.6993596217 41.9196891407 -0.4151177121
BXD45 m 106.275 14.1539223733 134.2768426836 78.2731573164
BXD48 m 25.9116 12.65965303 50.9572094943 0.8659905057
BXD48a m 16.6325 14.1539223733 44.6343426836 -11.3693426836
BXD49 m 56.856 12.65965303 81.9016094943 31.8103905057
BXD51 m 73.2228 12.65965303 98.2684094943 48.1771905057
BXD53 m 33.6635 14.1539223733 61.6653426836 5.6616573164
BXD55 m 39.084 12.65965303 64.1296094943 14.0383905057
BXD6 m 53.8852 12.65965303 78.9308094943 28.8395905057
BXD62 m 84.8404 12.65965303 109.8860094943 59.7947905057
BXD63 m 33.4165 14.1539223733 61.4183426836 5.4146573164
BXD64 m 35.2316 12.65965303 60.2772094943 10.1859905057
BXD66 m 22.5944 12.65965303 47.6400094943 -2.4512094943
BXD67 m 12.491 14.1539223733 40.4928426836 -15.5108426836
BXD69 m 31.0616 12.65965303 56.1072094943 6.0159905057
BXD73 m 38.2425 14.1539223733 66.2443426836 10.2406573164
BXD75 m 56.0888 12.65965303 81.1344094943 31.0431905057
BXD77 m 33.1552 12.65965303 58.2008094943 8.1095905057
BXD79 m 63.9384 12.65965303 88.9840094943 38.8927905057
BXD8 m 61.3596 12.65965303 86.4052094943 36.3139905057
BXD81 m 20.5563333333 16.3435417847 52.8900761557 -11.7774094891
BXD84 m 27.3064 12.65965303 52.3520094943 2.2607905057
BXD87 m 27.4004 12.65965303 52.4460094943 2.3547905057
BXD89 m 19.8712 12.65965303 44.9168094943 -5.1744094943
BXD90 m 14.7408 12.65965303 39.7864094943 -10.3048094943
C57BL/6J m 67.638 12.65965303 92.6836094943 42.5923905057
DBA/2J m 24.256 14.1539223733 52.2578426836 -3.7458426836




  GWAS USING LINEAR MIXED MODELS