Project measure / variable:   Schoonjans1   GCA_plasma_t30_CD

ID, description, units MPD:112696   GCA_plasma_t30_CD   plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means1.0723   ng/mL
Median of the strain means0.70893   ng/mL
SD of the strain means± 0.94619
Coefficient of variation (CV)0.8824
Min–max range of strain means0.04   –   3.3508   ng/mL
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 128.3244 3.7742 5.0553 < 0.0001
Residuals 109 81.3778 0.7466


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.56962 0.34172   5 0.15282 0.5999 0.114, 1.0281 -0.53
BXD100 m 0.5096 0.22644   5 0.10127 0.4443 0.314, 0.89 -0.59
BXD11 m 0.582 0.577   3 0.33313 0.9914 0.004, 1.158 -0.52
BXD12 m 1.4393 0.99664   3 0.57541 0.6924 0.804, 2.588 0.39
BXD27 m 0.2565 0.26488   4 0.13244 1.0327 0.032, 0.636 -0.86
BXD32 m 2.6224 0.56513   5 0.25273 0.2155 2.092, 3.51 1.64
BXD34 m 1.7244 1.0759   5 0.48115 0.6239 0.456, 2.944 0.69
BXD39 m 0.80667 0.71493   3 0.41277 0.8863 0.156, 1.572 -0.28
BXD40 m 2.851 1.5398   4 0.76989 0.5401 1.178, 4.344 1.88
BXD43 m 0.3115 0.36275   2   0.2565 1.1645 0.055, 0.568 -0.8
BXD45 m 0.6665 0.41029   4 0.20514 0.6156 0.294, 1.242 -0.43
BXD48 m 0.7212 0.49196   5 0.22001 0.6821 0.206, 1.35 -0.37
BXD48a m 0.36667 0.53348   3 0.30801 1.4549 0.034, 0.982 -0.75
BXD49 m 2.074 0.76511   5 0.34217 0.3689 0.862, 2.756 1.06
BXD51 m 0.27933 0.18472   3 0.10665 0.6613 0.074, 0.432 -0.84
BXD53 m 0.4125 0.49578   4 0.24789 1.2019 0.152, 1.156 -0.7
BXD55 m 1.2788 0.76391   5 0.34163 0.5974 0.462, 2.3 0.22
BXD6 m 0.69667 0.82934   3 0.47882 1.1904 0.026, 1.624 -0.4
BXD62 m 0.3852 0.16526   5 0.07391 0.429 0.182, 0.592 -0.73
BXD63 m 0.579 0.74426   4 0.37213 1.2854 0.122, 1.686 -0.52
BXD64 m 1.84 0.46516   5 0.20803 0.2528 1.494, 2.646 0.81
BXD66 m 0.04 0.0   1   0.0 0.0 0.04, 0.04 -1.09
BXD67 m 1.599 0.12125   4 0.06063 0.0758 1.504, 1.776 0.56
BXD69 m 0.9088 0.8701   5 0.38912 0.9574 0.262, 2.342 -0.17
BXD73 m 3.3395 1.8068   4 0.90341 0.541 1.36, 5.66 2.4
BXD75 m 2.4884 2.3686   5 1.0592 0.9518 0.248, 6.264 1.5
BXD77 m 0.8988 0.48171   5 0.21543 0.5359 0.47, 1.718 -0.18
BXD79 m 0.7328 0.57491   5 0.25711 0.7845 0.14, 1.552 -0.36
BXD8 m 0.53 0.24165   5 0.10807 0.4559 0.136, 0.788 -0.57
BXD81 m 0.76743 0.1705   2   0.12057 0.2222 0.64687, 0.888 -0.32
BXD84 m 0.40256 0.45749   5 0.2046 1.1364 0.00882353, 1.028 -0.71
BXD87 m 2.2192 1.499   5 0.67037 0.6755 0.998, 4.71 1.21
BXD89 m 0.165 0.11124   4 0.05562 0.6742 0.028, 0.294 -0.96
BXD90 m 0.099 0.0297   2   0.021 0.3 0.078, 0.12 -1.03
C57BL/6J m 3.3508 1.0539   5 0.4713 0.3145 1.632, 4.478 2.41
DBA/2J m 0.08867 0.06278   3 0.03625 0.708 0.018, 0.138 -1.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.56962 0.3864156116 1.3354831797 -0.1962431797
BXD100 m 0.5096 0.3864156116 1.2754631797 -0.2562631797
BXD11 m 0.582 0.4988604095 1.5707251135 -0.4067251135
BXD12 m 1.4393333333 0.4988604095 2.4280584469 0.4506082198
BXD27 m 0.2565 0.4320257876 1.1127610657 -0.5997610657
BXD32 m 2.6224 0.3864156116 3.3882631797 1.8565368203
BXD34 m 1.7244 0.3864156116 2.4902631797 0.9585368203
BXD39 m 0.8066666667 0.4988604095 1.7953917802 -0.1820584469
BXD40 m 2.851 0.4320257876 3.7072610657 1.9947389343
BXD43 m 0.3115 0.6109767281 1.522436012 -0.899436012
BXD45 m 0.6665 0.4320257876 1.5227610657 -0.1897610657
BXD48 m 0.7212 0.3864156116 1.4870631797 -0.0446631797
BXD48a m 0.3666666667 0.4988604095 1.3553917802 -0.6220584469
BXD49 m 2.074 0.3864156116 2.8398631797 1.3081368203
BXD51 m 0.2793333333 0.4988604095 1.2680584469 -0.7093917802
BXD53 m 0.4125 0.4320257876 1.2687610657 -0.4437610657
BXD55 m 1.2788 0.3864156116 2.0446631797 0.5129368203
BXD6 m 0.6966666667 0.4988604095 1.6853917802 -0.2920584469
BXD62 m 0.3852 0.3864156116 1.1510631797 -0.3806631797
BXD63 m 0.579 0.4320257876 1.4352610657 -0.2772610657
BXD64 m 1.84 0.3864156116 2.6058631797 1.0741368203
BXD67 m 1.599 0.4320257876 2.4552610657 0.7427389343
BXD69 m 0.9088 0.3864156116 1.6746631797 0.1429368203
BXD73 m 3.3395 0.4320257876 4.1957610657 2.4832389343
BXD75 m 2.4884 0.3864156116 3.2542631797 1.7225368203
BXD77 m 0.8988 0.3864156116 1.6646631797 0.1329368203
BXD79 m 0.7328 0.3864156116 1.4986631797 -0.0330631797
BXD8 m 0.53 0.3864156116 1.2958631797 -0.2358631797
BXD81 m 0.767435 0.6109767281 1.978371012 -0.443501012
BXD84 m 0.402564706 0.3864156116 1.1684278857 -0.3632984737
BXD87 m 2.2192 0.3864156116 2.9850631797 1.4533368203
BXD89 m 0.165 0.4320257876 1.0212610657 -0.6912610657
BXD90 m 0.099 0.6109767281 1.309936012 -1.111936012
C57BL/6J m 3.3508 0.3864156116 4.1166631797 2.5849368203
DBA/2J m 0.0886666667 0.4988604095 1.0773917802 -0.9000584469




  GWAS USING LINEAR MIXED MODELS