Project measure / variable:   Schoonjans1   DCA_plasma_t30_CD

ID, description, units MPD:112694   DCA_plasma_t30_CD   plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means42.939   ng/mL
Median of the strain means26.773   ng/mL
SD of the strain means± 32.579
Coefficient of variation (CV)0.7587
Min–max range of strain means0.161   –   110.7   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 172856.2413 4938.7498 5.6127 < 0.0001
Residuals 129 113510.5598 879.9268


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 77.55 20.28   5 9.0693 0.2615 57.52, 105.9 1.06
BXD100 m 21.644 5.4852   5 2.453 0.2534 13.676, 28.25 -0.65
BXD11 m 19.151 11.886   4 5.9428 0.6206 5.294, 30.652 -0.73
BXD12 m 8.3513 6.9987   3 4.0407 0.838 3.422, 16.362 -1.06
BXD27 m 26.926 9.71   4 4.855 0.3606 16.336, 39.508 -0.49
BXD32 m 79.45 69.48   5 31.071 0.8745 11.788, 196.5 1.12
BXD34 m 16.56 1.4932   5 0.66779 0.0902 14.742, 18.208 -0.81
BXD39 m 19.989 4.8163   3 2.7807 0.2409 14.77, 24.262 -0.7
BXD40 m 16.995 5.1944   4 2.5972 0.3056 11.918, 24.154 -0.8
BXD43 m 7.5727 3.9497   7 1.4929 0.5216 1.746, 13.21 -1.09
BXD45 m 61.92 12.75   4 6.3751 0.2059 46.596, 77.33 0.58
BXD48 m 79.72 27.613   5 12.349 0.3464 50.61, 114.1 1.13
BXD48a m 21.704 13.36   4 6.6799 0.6155 9.654, 36.882 -0.65
BXD49 m 64.59 14.402   5 6.4409 0.223 48.25, 85.69 0.66
BXD51 m 16.193 6.4427   5 2.8813 0.3979 6.778, 23.462 -0.82
BXD53 m 47.014 28.758   4 14.379 0.6117 19.024, 85.33 0.13
BXD55 m 76.67 28.159   5 12.593 0.3673 53.91, 123.9 1.04
BXD6 m 0.161 0.15686   4 0.07843 0.9743 0.016, 0.382 -1.31
BXD62 m 62.37 25.081   5 11.217 0.4021 21.306, 85.73 0.6
BXD63 m 66.91 18.551   4 9.2757 0.2773 49.306, 84.61 0.74
BXD64 m 8.2596 2.3403   5 1.0466 0.2833 5.946, 11.248 -1.06
BXD66 m 14.055 6.5041   5 2.9087 0.4628 7.084, 24.27 -0.89
BXD67 m 12.943 6.874   4 3.437 0.5311 4.06, 19.496 -0.92
BXD69 m 44.548 18.984   5 8.4897 0.4261 29.034, 67.87 0.05
BXD73 m 88.29 77.99   4 38.993 0.8833 0.504, 189.3 1.39
BXD75 m 85.76 14.629   5 6.5421 0.1706 70.08, 101.0 1.31
BXD77 m 21.878 12.708   5 5.683 0.5808 7.104, 41.96 -0.65
BXD79 m 82.33 91.6   5 40.964 1.1126 11.804, 238.0 1.21
BXD8 m 10.856 2.6866   5 1.2015 0.2475 7.988, 15.084 -0.98
BXD81 m 87.52 60.76   3 35.078 0.6942 28.888, 150.2 1.37
BXD84 m 39.997 10.118   5 4.525 0.253 24.736, 48.616 -0.09
BXD87 m 97.57 37.713   5 16.866 0.3865 56.93, 138.5 1.68
BXD89 m 16.362 7.6761   5 3.4329 0.4691 9.072, 25.668 -0.82
BXD90 m 6.6656 2.2399   5 1.0017 0.336 4.126, 9.268 -1.11
C57BL/6J m 110.7 44.744   5 20.01 0.4043 55.11, 171.7 2.08
DBA/2J m 26.62 9.5851   4 4.7925 0.3601 13.538, 36.516 -0.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 77.552 13.2659475351 103.7990021009 51.3049978991
BXD100 m 21.6444 13.2659475351 47.8914021009 -4.6026021009
BXD11 m 19.151 14.8317802372 48.4960404516 -10.1940404516
BXD12 m 8.3513333333 17.1262646251 42.2360673416 -25.5334006749
BXD27 m 26.926 14.8317802372 56.2710404516 -2.4190404516
BXD32 m 79.4516 13.2659475351 105.6986021009 53.2045978991
BXD34 m 16.56 13.2659475351 42.8070021009 -9.6870021009
BXD39 m 19.9893333333 17.1262646251 53.8740673416 -13.8954006749
BXD40 m 16.9955 14.8317802372 46.3405404516 -12.3495404516
BXD43 m 7.5727142857 11.2117720023 29.7554797852 -14.6100512137
BXD45 m 61.924 14.8317802372 91.2690404516 32.5789595484
BXD48 m 79.72 13.2659475351 105.9670021009 53.4729978991
BXD48a m 21.7045 14.8317802372 51.0495404516 -7.6405404516
BXD49 m 64.594 13.2659475351 90.8410021009 38.3469978991
BXD51 m 16.1928 13.2659475351 42.4398021009 -10.0542021009
BXD53 m 47.0145 14.8317802372 76.3595404516 17.6694595484
BXD55 m 76.67 13.2659475351 102.9170021009 50.4229978991
BXD6 m 0.161 14.8317802372 29.5060404516 -29.1840404516
BXD62 m 62.3732 13.2659475351 88.6202021009 36.1261978991
BXD63 m 66.9065 14.8317802372 96.2515404516 37.5614595484
BXD64 m 8.2596 13.2659475351 34.5066021009 -17.9874021009
BXD66 m 14.0552 13.2659475351 40.3022021009 -12.1918021009
BXD67 m 12.943 14.8317802372 42.2880404516 -16.4020404516
BXD69 m 44.5484 13.2659475351 70.7954021009 18.3013978991
BXD73 m 88.291 14.8317802372 117.6360404516 58.9459595484
BXD75 m 85.758 13.2659475351 112.0050021009 59.5109978991
BXD77 m 21.8776 13.2659475351 48.1246021009 -4.3694021009
BXD79 m 82.3272 13.2659475351 108.5742021009 56.0801978991
BXD8 m 10.8564 13.2659475351 37.1034021009 -15.3906021009
BXD81 m 87.5193333333 17.1262646251 121.4040673416 53.6345993251
BXD84 m 39.997 13.2659475351 66.2440021009 13.7499978991
BXD87 m 97.574 13.2659475351 123.8210021009 71.3269978991
BXD89 m 16.362 13.2659475351 42.6090021009 -9.8850021009
BXD90 m 6.6656 13.2659475351 32.9126021009 -19.5814021009
C57BL/6J m 110.682 13.2659475351 136.9290021009 84.4349978991
DBA/2J m 26.62 14.8317802372 55.9650404516 -2.7250404516




  GWAS USING LINEAR MIXED MODELS