Project measure / variable:   Schoonjans1   CDCA_plasma_t30_HFD

ID, description, units MPD:112693   CDCA_plasma_t30_HFD   plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means1.8088   ng/mL
Median of the strain means1.2742   ng/mL
SD of the strain means± 2.0417
Coefficient of variation (CV)1.1288
Min–max range of strain means0.15653   –   11.137   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 683.019 19.5148 1.0388 0.4253
Residuals 116 2179.1775 18.786


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.4765 0.7116   5 0.31824 0.4819 0.52, 2.34 -0.16
BXD100 m 0.3745 0.64616   8 0.22845 1.7254 0.01, 1.944 -0.7
BXD11 m 3.2247 2.825   3 1.631 0.8761 0.184, 5.768 0.69
BXD12 m 1.749 1.4367   4 0.71836 0.8215 0.272, 3.664 -0.03
BXD27 m 4.842 8.5544   5 3.8256 1.7667 0.448, 20.112 1.49
BXD32 m 1.417 1.0957   4 0.54783 0.7732 0.496, 2.718 -0.19
BXD34 m 1.0075 0.78015   4 0.39008 0.7743 0.374, 2.066 -0.39
BXD39 m 1.4233 0.64909   3 0.37475 0.456 0.768, 2.066 -0.19
BXD40 m 2.5355 1.4966   4 0.74832 0.5903 1.096, 4.06 0.36
BXD43 m 0.15653 0.15481   2   0.10947 0.989 0.04706, 0.266 -0.81
BXD45 m 1.8812 0.75715   5 0.33861 0.4025 1.248, 2.944 0.04
BXD48 m 0.8652 1.2938   5 0.57863 1.4954 0.1, 3.154 -0.46
BXD48a m 1.447 1.2059   4 0.60293 0.8334 0.662, 3.244 -0.18
BXD49 m 11.137 19.841   5 8.873 1.7815 0.402, 46.32 4.57
BXD51 m 0.39887 0.00160513   2   0.001135 0.004 0.39773, 0.4 -0.69
BXD53 m 1.1052 0.36862   5 0.16485 0.3335 0.67, 1.554 -0.34
BXD55 m 3.9368 4.5986   5 2.0565 1.1681 0.812, 11.902 1.04
BXD6 m 1.9496 1.5318   5 0.68503 0.7857 0.324, 4.3526 0.07
BXD62 m 3.64 5.5316   4 2.7658 1.5197 0.506, 11.928 0.9
BXD63 m 0.4388 0.25563   5 0.11432 0.5826 0.168, 0.838 -0.67
BXD64 m 1.0152 0.69942   5 0.31279 0.6889 0.488, 2.198 -0.39
BXD66 m 0.587 0.16263   2   0.115 0.2771 0.472, 0.702 -0.6
BXD67 m 0.6866 0.46768   5 0.20915 0.6812 0.098, 1.405 -0.55
BXD69 m 5.6385 4.006   4 2.003 0.7105 2.68, 11.516 1.88
BXD73 m 1.4373 1.2896   3 0.74452 0.8972 0.546, 2.916 -0.18
BXD75 m 1.4025 1.128   4 0.56398 0.8043 0.078, 2.62 -0.2
BXD77 m 0.8412 0.38954   5 0.17421 0.4631 0.246, 1.262 -0.47
BXD79 m 1.8776 0.58967   5 0.26371 0.3141 1.202, 2.554 0.03
BXD8 m 1.146 0.77493   3 0.44741 0.6762 0.33, 1.872 -0.32
BXD81 m 0.738 0.3292   5 0.14722 0.4461 0.444, 1.164 -0.52
BXD84 m 0.3349 0.28977   5 0.12959 0.8652 0.1125, 0.822 -0.72
BXD87 m 0.984 0.66228   4 0.33114 0.6731 0.364, 1.85 -0.4
BXD89 m 1.4968 1.1511   5 0.51477 0.769 0.708, 3.478 -0.15
BXD90 m 0.8355 0.98511   4 0.49255 1.1791 0.274, 2.308 -0.48
C57BL/6J m 0.70533 0.29155   3 0.16833 0.4134 0.404, 0.986 -0.54
DBA/2J m 0.3838 0.0874   3 0.05046 0.2277 0.308, 0.47941 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.47652 1.9383504661 5.315667335 -2.362627335
BXD100 m 0.3745 1.5324005941 3.4096124629 -2.6606124629
BXD11 m 3.2246666667 2.5023996914 8.1809845641 -1.7316512307
BXD12 m 1.749 2.1671417032 6.0412972084 -2.5432972084
BXD27 m 4.842 1.9383504661 8.681147335 1.002852665
BXD32 m 1.417 2.1671417032 5.7092972084 -2.8752972084
BXD34 m 1.0075 2.1671417032 5.2997972084 -3.2847972084
BXD39 m 1.4233333333 2.5023996914 6.3796512307 -3.5329845641
BXD40 m 2.5355 2.1671417032 6.8277972084 -1.7567972084
BXD43 m 0.15653 3.0648011883 6.2267549258 -5.9136949258
BXD45 m 1.8812 1.9383504661 5.720347335 -1.957947335
BXD48 m 0.8652 1.9383504661 4.704347335 -2.973947335
BXD48a m 1.447 2.1671417032 5.7392972084 -2.8452972084
BXD49 m 11.1368 1.9383504661 14.975947335 7.297652665
BXD51 m 0.398865 3.0648011883 6.4690899258 -5.6713599258
BXD53 m 1.1052 1.9383504661 4.944347335 -2.733947335
BXD55 m 3.9368 1.9383504661 7.775947335 0.097652665
BXD6 m 1.94958 1.9383504661 5.788727335 -1.889567335
BXD62 m 3.64 2.1671417032 7.9322972084 -0.6522972084
BXD63 m 0.4388 1.9383504661 4.277947335 -3.400347335
BXD64 m 1.0152 1.9383504661 4.854347335 -2.823947335
BXD66 m 0.587 3.0648011883 6.6572249258 -5.4832249258
BXD67 m 0.6866 1.9383504661 4.525747335 -3.152547335
BXD69 m 5.6385 2.1671417032 9.9307972084 1.3462027916
BXD73 m 1.4373333333 2.5023996914 6.3936512307 -3.5189845641
BXD75 m 1.4025 2.1671417032 5.6947972084 -2.8897972084
BXD77 m 0.8412 1.9383504661 4.680347335 -2.997947335
BXD79 m 1.8776 1.9383504661 5.716747335 -1.961547335
BXD8 m 1.146 2.5023996914 6.1023178974 -3.8103178974
BXD81 m 0.738 1.9383504661 4.577147335 -3.101147335
BXD84 m 0.3349 1.9383504661 4.174047335 -3.504247335
BXD87 m 0.984 2.1671417032 5.2762972084 -3.3082972084
BXD89 m 1.4968 1.9383504661 5.335947335 -2.342347335
BXD90 m 0.8355 2.1671417032 5.1277972084 -3.4567972084
C57BL/6J m 0.7053333333 2.5023996914 5.6616512307 -4.2509845641
DBA/2J m 0.3838033333 2.5023996914 5.3401212307 -4.5725145641




  GWAS USING LINEAR MIXED MODELS