Project measure / variable:   Schoonjans1   CA_plasma_t30_HFD

ID, description, units MPD:112691   CA_plasma_t30_HFD   plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means13.127   ng/mL
Median of the strain means8.6219   ng/mL
SD of the strain means± 13.207
Coefficient of variation (CV)1.0061
Min–max range of strain means0.33065   –   52.82   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 26683.2835 762.3795 1.5749 0.0382
Residuals 116 56154.3773 484.0895


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 9.4665 9.613   5 4.2991 1.0155 0.762, 24.491 -0.28
BXD100 m 1.6929 1.9495   7 0.73685 1.1516 0.012, 5.5 -0.87
BXD11 m 10.352 7.422   3 4.2851 0.717 2.472, 17.21 -0.21
BXD12 m 6.8355 7.9683   4 3.9842 1.1657 0.204, 17.83 -0.48
BXD27 m 44.038 66.84   4 33.419 1.5177 0.58, 143.7 2.34
BXD32 m 11.223 10.162   4 5.0812 0.9055 2.234, 21.642 -0.14
BXD34 m 11.104 9.4   4 4.7 0.8466 2.502, 23.134 -0.15
BXD39 m 7.3987 6.2781   3 3.6246 0.8485 0.37, 12.45 -0.43
BXD40 m 32.689 26.192   4 13.096 0.8013 8.448, 62.03 1.48
BXD43 m 0.33065 0.274   4 0.137 0.8287 0.096, 0.72059 -0.97
BXD45 m 5.0004 1.322   5 0.59122 0.2644 3.376, 6.428 -0.62
BXD48 m 11.986 13.4   4 6.7001 1.1179 0.304, 27.78 -0.09
BXD48a m 12.713 5.3118   4 2.6559 0.4178 7.682, 20.214 -0.03
BXD49 m 52.82 69.16   5 30.93 1.3093 3.402, 158.7 3.01
BXD51 m 2.2268 1.6867   3 0.97381 0.7574 0.84, 4.1045 -0.83
BXD53 m 5.9532 4.2327   5 1.8929 0.711 2.922, 12.75 -0.54
BXD55 m 22.479 25.429   5 11.372 1.1312 3.984, 66.09 0.71
BXD6 m 28.907 31.965   5 14.295 1.1058 3.084, 75.73 1.19
BXD62 m 13.119 19.378   4 9.6892 1.4771 2.546, 42.128 0.0
BXD63 m 10.401 11.239   5 5.0264 1.0806 1.316, 29.894 -0.21
BXD64 m 6.8768 5.5099   5 2.4641 0.8012 1.356, 13.528 -0.47
BXD66 m 3.8513 1.4049   3 0.81114 0.3648 2.282, 4.992 -0.7
BXD67 m 13.641 13.704   5 6.1284 1.0046 2.438, 37.485 0.04
BXD69 m 44.391 35.576   4 17.788 0.8014 6.31, 86.44 2.37
BXD73 m 10.84 10.68   3 6.1664 0.9853 2.548, 22.892 -0.17
BXD75 m 34.971 43.115   4 21.558 1.2329 1.398, 98.17 1.65
BXD77 m 7.7772 4.3923   5 1.9643 0.5648 0.5, 11.09 -0.41
BXD79 m 4.0452 2.9682   5 1.3274 0.7338 1.798, 9.074 -0.69
BXD8 m 6.7127 8.6073   3 4.9694 1.2822 0.04, 16.428 -0.49
BXD81 m 7.0124 3.867   5 1.7294 0.5514 1.924, 12.128 -0.46
BXD84 m 3.1304 2.6849   5 1.2007 0.8577 0.614, 6.238 -0.76
BXD87 m 4.558 5.4804   4 2.7402 1.2024 1.394, 12.738 -0.65
BXD89 m 6.26 7.2887   5 3.2596 1.1643 0.604, 18.506 -0.52
BXD90 m 2.362 2.1152   3 1.2212 0.8955 0.97, 4.796 -0.82
C57BL/6J m 12.396 4.7098   3 2.7192 0.3799 7.162, 16.292 -0.06
DBA/2J m 3.0243 2.9925   3 1.7277 0.9895 0.92, 6.45 -0.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 9.46646 9.8396083188 28.9550440903 -10.0221240903
BXD100 m 1.6928571429 8.3159868355 18.1637169054 -14.7780026197
BXD11 m 10.352 12.7028797173 35.5116538743 -14.8076538743
BXD12 m 6.8355 11.0010165364 28.6243994056 -14.9533994056
BXD27 m 44.038 11.0010165364 65.8268994056 22.2491005944
BXD32 m 11.223 11.0010165364 33.0118994056 -10.5658994056
BXD34 m 11.1035 11.0010165364 32.8923994056 -10.6853994056
BXD39 m 7.3986666667 12.7028797173 32.558320541 -17.7609872076
BXD40 m 32.689 11.0010165364 54.4778994056 10.9001005944
BXD43 m 0.3306475 11.0010165364 22.1195469056 -21.4582519056
BXD45 m 5.0004 9.8396083188 24.4889840903 -14.4881840903
BXD48 m 11.9865 11.0010165364 33.7753994056 -9.8023994056
BXD48a m 12.713 11.0010165364 34.5018994056 -9.0758994056
BXD49 m 52.8216 9.8396083188 72.3101840903 33.3330159097
BXD51 m 2.2268333333 12.7028797173 27.3864872076 -22.932820541
BXD53 m 5.9532 9.8396083188 25.4417840903 -13.5353840903
BXD55 m 22.4792 9.8396083188 41.9677840903 2.9906159097
BXD6 m 28.9068 9.8396083188 48.3953840903 9.4182159097
BXD62 m 13.119 11.0010165364 34.9078994056 -8.6698994056
BXD63 m 10.4012 9.8396083188 29.8897840903 -9.0873840903
BXD64 m 6.8768 9.8396083188 26.3653840903 -12.6117840903
BXD66 m 3.8513333333 12.7028797173 29.0109872076 -21.308320541
BXD67 m 13.641 9.8396083188 33.1295840903 -5.8475840903
BXD69 m 44.3905 11.0010165364 66.1793994056 22.6016005944
BXD73 m 10.84 12.7028797173 35.9996538743 -14.3196538743
BXD75 m 34.9705 11.0010165364 56.7593994056 13.1816005944
BXD77 m 7.7772 9.8396083188 27.2657840903 -11.7113840903
BXD79 m 4.0452 9.8396083188 23.5337840903 -15.4433840903
BXD8 m 6.7126666667 12.7028797173 31.872320541 -18.4469872076
BXD81 m 7.0124 9.8396083188 26.5009840903 -12.4761840903
BXD84 m 3.1304 9.8396083188 22.6189840903 -16.3581840903
BXD87 m 4.558 11.0010165364 26.3468994056 -17.2308994056
BXD89 m 6.26 9.8396083188 25.7485840903 -13.2285840903
BXD90 m 2.362 12.7028797173 27.5216538743 -22.7976538743
C57BL/6J m 12.396 12.7028797173 37.5556538743 -12.7636538743
DBA/2J m 3.0243 12.7028797173 28.1839538743 -22.1353538743




  GWAS USING LINEAR MIXED MODELS