Project measure / variable:   Schoonjans1   bMCA_plasma_t30_HFD

ID, description, units MPD:112689   bMCA_plasma_t30_HFD   plasma bile acid β-muricholic acid, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid β-muricholic acid, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means41.995   ng/mL
Median of the strain means28.633   ng/mL
SD of the strain means± 45.911
Coefficient of variation (CV)1.0933
Min–max range of strain means3.16   –   229.6   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 314325.5967 8980.7313 1.6292 0.0274
Residuals 122 672527.0098 5512.5165


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 39.543 25.288   5 11.309 0.6395 5.248, 68.1 -0.05
BXD100 m 11.198 6.8115   9 2.2705 0.6083 3.862, 23.568 -0.67
BXD11 m 105.5 69.56   3 40.16 0.6595 40.566, 178.9 1.38
BXD12 m 68.68 77.18   4 38.59 1.1237 14.888, 180.4 0.58
BXD27 m 57.83 54.12   5 24.201 0.9358 7.854, 119.3 0.34
BXD32 m 39.017 23.25   4 11.625 0.5959 14.344, 68.53 -0.06
BXD34 m 30.425 6.7056   4 3.3528 0.2204 21.914, 37.91 -0.25
BXD39 m 9.7967 2.6959   3 1.5565 0.2752 7.896, 12.882 -0.7
BXD40 m 79.75 60.85   4 30.426 0.7631 27.214, 154.5 0.82
BXD43 m 19.981 13.262   5 5.931 0.6637 7.332, 39.832 -0.48
BXD45 m 37.358 16.082   5 7.192 0.4305 17.866, 52.49 -0.1
BXD48 m 7.8148 6.3435   5 2.8369 0.8117 2.722, 18.196 -0.74
BXD48a m 18.41 10.042   4 5.021 0.5454 13.158, 33.468 -0.51
BXD49 m 60.53 74.96   5 33.522 1.2383 11.944, 188.0 0.4
BXD51 m 9.891 6.7809   3 3.9149 0.6856 2.292, 15.325 -0.7
BXD53 m 12.657 10.354   5 4.6303 0.818 3.756, 30.28 -0.64
BXD55 m 40.358 28.049   5 12.544 0.695 15.19, 86.98 -0.04
BXD6 m 172.6 279.8   5 125.1 1.6211 28.762, 671.8 2.84
BXD62 m 229.6 286.1   4 143.1 1.2461 44.108, 650.4 4.09
BXD63 m 23.664 10.368   5 4.6366 0.4381 10.468, 37.568 -0.4
BXD64 m 13.886 12.51   5 5.5947 0.9009 5.216, 35.976 -0.61
BXD66 m 25.776 27.265   3 15.742 1.0578 7.92, 57.16 -0.35
BXD67 m 26.84 20.238   5 9.0509 0.7541 9.15, 55.57 -0.33
BXD69 m 15.441 5.6261   4 2.813 0.3644 10.182, 23.07 -0.58
BXD73 m 57.29 40.856   3 23.588 0.7131 31.538, 104.4 0.33
BXD75 m 32.826 44.226   4 22.113 1.3473 8.338, 99.0 -0.2
BXD77 m 20.039 8.8121   5 3.9409 0.4398 12.374, 34.648 -0.48
BXD79 m 65.74 31.849   5 14.243 0.4845 27.948, 99.51 0.52
BXD8 m 43.885 3.7702   3 2.1767 0.0859 40.006, 47.536 0.04
BXD81 m 23.116 9.6046   5 4.2953 0.4155 10.494, 34.83 -0.41
BXD84 m 42.178 51.27   5 22.928 1.2156 8.836, 132.5 0.0
BXD87 m 33.606 18.944   4 9.4719 0.5637 18.284, 58.83 -0.18
BXD89 m 14.453 9.7337   5 4.353 0.6735 5.632, 29.45 -0.6
BXD90 m 9.0691 6.4924   4 3.2462 0.7159 4.5882, 18.672 -0.72
C57BL/6J m 3.16 1.6231   3 0.93712 0.5136 1.29, 4.204 -0.85
DBA/2J m 9.9133 4.8642   3 2.8083 0.4907 7.1, 15.53 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 39.5432 33.2039650456 105.2737651695 -26.1873651695
BXD100 m 11.198 24.7487743215 60.1906706395 -37.7946706395
BXD11 m 105.472 42.8661345499 190.3297947461 20.6142052539
BXD12 m 68.6845 37.1231614822 142.1735059592 -4.8045059592
BXD27 m 57.8276 33.2039650456 123.5581651695 -7.9029651695
BXD32 m 39.017 37.1231614822 112.5060059592 -34.4720059592
BXD34 m 30.4245 37.1231614822 103.9135059592 -43.0645059592
BXD39 m 9.7966666667 42.8661345499 94.6544614128 -75.0611280794
BXD40 m 79.749 37.1231614822 153.2380059592 6.2599940408
BXD43 m 19.98096 33.2039650456 85.7115251695 -45.7496051695
BXD45 m 37.3576 33.2039650456 103.0881651695 -28.3729651695
BXD48 m 7.8148 33.2039650456 73.5453651695 -57.9157651695
BXD48a m 18.4105 37.1231614822 91.8995059592 -55.0785059592
BXD49 m 60.5312 33.2039650456 126.2617651695 -5.1993651695
BXD51 m 9.891 42.8661345499 94.7487947461 -74.9667947461
BXD53 m 12.6568 33.2039650456 78.3873651695 -53.0737651695
BXD55 m 40.3584 33.2039650456 106.0889651695 -25.3721651695
BXD6 m 172.59 33.2039650456 238.3205651695 106.8594348305
BXD62 m 229.6145 37.1231614822 303.1035059592 156.1254940408
BXD63 m 23.6644 33.2039650456 89.3949651695 -42.0661651695
BXD64 m 13.8864 33.2039650456 79.6169651695 -51.8441651695
BXD66 m 25.776 42.8661345499 110.6337947461 -59.0817947461
BXD67 m 26.8396 33.2039650456 92.5701651695 -38.8909651695
BXD69 m 15.4405 37.1231614822 88.9295059592 -58.0485059592
BXD73 m 57.292 42.8661345499 142.1497947461 -27.5657947461
BXD75 m 32.8265 37.1231614822 106.3155059592 -40.6625059592
BXD77 m 20.0388 33.2039650456 85.7693651695 -45.6917651695
BXD79 m 65.7368 33.2039650456 131.4673651695 0.0062348305
BXD8 m 43.8853333333 42.8661345499 128.7431280794 -40.9724614128
BXD81 m 23.1156 33.2039650456 88.8461651695 -42.6149651695
BXD84 m 42.1778 33.2039650456 107.9083651695 -23.5527651695
BXD87 m 33.6065 37.1231614822 107.0955059592 -39.8825059592
BXD89 m 14.4528 33.2039650456 80.1833651695 -51.2777651695
BXD90 m 9.06905 37.1231614822 82.5580559592 -64.4199559592
C57BL/6J m 3.16 42.8661345499 88.0177947461 -81.6977947461
DBA/2J m 9.9133333333 42.8661345499 94.7711280794 -74.9444614128




  GWAS USING LINEAR MIXED MODELS