Project measure / variable:   Schoonjans1   bMCA_plasma_t30_CD

ID, description, units MPD:112688   bMCA_plasma_t30_CD   plasma bile acid β-muricholic acid, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid β-muricholic acid, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means42.093   ng/mL
Median of the strain means21.869   ng/mL
SD of the strain means± 47.6
Coefficient of variation (CV)1.1308
Min–max range of strain means3.8388   –   211.9   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 354246.4363 10121.3268 1.6295 0.0263
Residuals 129 801239.5112 6211.159


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 53.98 111.4   5 49.802 2.0629 1.816, 253.1 0.25
BXD100 m 12.898 14.235   5 6.3662 1.1036 4.466, 38.268 -0.61
BXD11 m 17.337 10.988   4 5.4941 0.6338 8.136, 31.828 -0.52
BXD12 m 21.664 18.833   3 10.873 0.8693 6.676, 42.804 -0.43
BXD27 m 211.9 312.7   4 156.4 1.4756 24.678, 679.0 3.57
BXD32 m 131.2 227.1   5 101.5 1.7309 3.874, 532.3 1.87
BXD34 m 33.505 19.087   5 8.536 0.5697 14.114, 55.98 -0.18
BXD39 m 39.353 63.53   3 36.677 1.6143 1.792, 112.7 -0.06
BXD40 m 112.6 103.0   4 51.52 0.9151 16.12, 257.2 1.48
BXD43 m 11.003 15.759   7 5.9565 1.4323 1.114, 46.144 -0.65
BXD45 m 37.77 37.695   4 18.847 0.998 3.876, 91.62 -0.09
BXD48 m 6.6144 5.094   5 2.2781 0.7701 1.562, 12.378 -0.75
BXD48a m 7.156 0.94858   4 0.47429 0.1326 6.306, 8.14 -0.73
BXD49 m 17.613 10.39   5 4.6463 0.5899 2.79, 28.76 -0.51
BXD51 m 11.97 10.579   5 4.731 0.8838 2.63, 28.84 -0.63
BXD53 m 8.96 7.4037   4 3.7019 0.8263 2.8, 19.674 -0.7
BXD55 m 73.52 69.88   5 31.253 0.9506 10.13, 162.6 0.66
BXD6 m 162.7 150.9   5 67.48 0.9277 42.154, 341.6 2.53
BXD62 m 79.81 32.266   5 14.43 0.4043 43.836, 118.5 0.79
BXD63 m 3.915 2.8178   4 1.4089 0.7197 1.728, 7.684 -0.8
BXD64 m 11.815 4.5176   5 2.0204 0.3824 6.024, 16.502 -0.64
BXD66 m 14.44 6.1866   5 2.7667 0.4284 6.346, 22.948 -0.58
BXD67 m 24.898 16.274   4 8.137 0.6536 6.306, 44.566 -0.36
BXD69 m 6.422 6.5103   5 2.9115 1.0137 1.888, 17.938 -0.75
BXD73 m 86.31 136.1   3 78.57 1.5767 4.41, 243.4 0.93
BXD75 m 22.074 14.454   5 6.4642 0.6548 9.402, 38.144 -0.42
BXD77 m 56.31 65.99   5 29.511 1.1719 14.404, 171.4 0.3
BXD79 m 24.329 32.832   5 14.683 1.3495 4.164, 82.46 -0.37
BXD8 m 18.77 14.551   5 6.5075 0.7752 6.434, 43.456 -0.49
BXD81 m 49.202 58.8   3 33.949 1.1951 15.212, 117.1 0.15
BXD84 m 9.4524 4.2775   5 1.913 0.4525 4.614, 16.1 -0.69
BXD87 m 39.074 44.489   5 19.896 1.1386 11.408, 117.4 -0.06
BXD89 m 14.144 20.257   5 9.0592 1.4322 2.4, 49.698 -0.59
BXD90 m 3.8388 4.6754   5 2.0909 1.2179 1.42, 12.184 -0.8
C57BL/6J m 60.79 44.397   5 19.855 0.7303 26.518, 135.4 0.39
DBA/2J m 18.0 17.315   4 8.6573 0.9619 8.038, 43.86 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 53.9828 35.2453089117 123.7165068916 -15.7509068916
BXD100 m 12.8984 35.2453089117 82.6321068916 -56.8353068916
BXD11 m 17.337 39.4054533073 95.3016544663 -60.6276544663
BXD12 m 21.664 45.501498149 111.6898284868 -68.3618284868
BXD27 m 211.9195 39.4054533073 289.8841544663 133.9548455337
BXD32 m 131.1844 35.2453089117 200.9181068916 61.4506931084
BXD34 m 33.5048 35.2453089117 103.2385068916 -36.2289068916
BXD39 m 39.3526666667 45.501498149 129.3784951535 -50.6731618202
BXD40 m 112.6075 39.4054533073 190.5721544663 34.6428455337
BXD43 m 11.0028571429 29.787722786 69.9385962203 -47.9328819346
BXD45 m 37.77 39.4054533073 115.7346544663 -40.1946544663
BXD48 m 6.6144 35.2453089117 76.3481068916 -63.1193068916
BXD48a m 7.156 39.4054533073 85.1206544663 -70.8086544663
BXD49 m 17.6132 35.2453089117 87.3469068916 -52.1205068916
BXD51 m 11.9696 35.2453089117 81.7033068916 -57.7641068916
BXD53 m 8.96 39.4054533073 86.9246544663 -69.0046544663
BXD55 m 73.5152 35.2453089117 143.2489068916 3.7814931084
BXD6 m 162.6548 35.2453089117 232.3885068916 92.9210931084
BXD62 m 79.8144 35.2453089117 149.5481068916 10.0806931084
BXD63 m 3.915 39.4054533073 81.8796544663 -74.0496544663
BXD64 m 11.8152 35.2453089117 81.5489068916 -57.9185068916
BXD66 m 14.44 35.2453089117 84.1737068916 -55.2937068916
BXD67 m 24.8975 39.4054533073 102.8621544663 -53.0671544663
BXD69 m 6.422 35.2453089117 76.1557068916 -63.3117068916
BXD73 m 86.3093333333 45.501498149 176.3351618202 -3.7164951535
BXD75 m 22.074 35.2453089117 91.8077068916 -47.6597068916
BXD77 m 56.3068 35.2453089117 126.0405068916 -13.4269068916
BXD79 m 24.3292 35.2453089117 94.0629068916 -45.4045068916
BXD8 m 18.7696 35.2453089117 88.5033068916 -50.9641068916
BXD81 m 49.202 45.501498149 139.2278284868 -40.8238284868
BXD84 m 9.4524 35.2453089117 79.1861068916 -60.2813068916
BXD87 m 39.074 35.2453089117 108.8077068916 -30.6597068916
BXD89 m 14.1444 35.2453089117 83.8781068916 -55.5893068916
BXD90 m 3.8388 35.2453089117 73.5725068916 -65.8949068916
C57BL/6J m 60.7948 35.2453089117 130.5285068916 -8.9389068916
DBA/2J m 18.0 39.4054533073 95.9646544663 -59.9646544663




  GWAS USING LINEAR MIXED MODELS