Project measure / variable:   Schoonjans1   aMCA_plasma_t30_HFD

ID, description, units MPD:112687   aMCA_plasma_t30_HFD   plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means7.2644   ng/mL
Median of the strain means5.4288   ng/mL
SD of the strain means± 6.132
Coefficient of variation (CV)0.8441
Min–max range of strain means1.629   –   27.439   ng/mL
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 5036.6926 148.138 1.0072 0.4708
Residuals 105 15442.8173 147.0745


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 6.3126 5.8273   4 2.9137 0.9231 2.154, 14.941 -0.16
BXD100 m 2.7376 1.5367   5 0.68725 0.5613 1.068, 4.13 -0.74
BXD11 m 6.07 3.2289   3 1.8642 0.532 3.08, 9.494 -0.19
BXD12 m 27.284 48.891   4 24.446 1.7919 1.37, 100.6 3.26
BXD27 m 15.572 18.139   4 9.0697 1.1649 2.466, 42.25 1.35
BXD32 m 4.0045 2.9711   4 1.4855 0.7419 1.326, 7.71 -0.53
BXD34 m 4.7625 2.386   4 1.193 0.501 1.872, 7.572 -0.41
BXD39 m 5.269 3.7689   2   2.665 0.7153 2.604, 7.934 -0.33
BXD40 m 11.043 7.4114   4 3.7057 0.6711 4.064, 18.184 0.62
BXD43 m 1.629 0.28991   2   0.205 0.178 1.424, 1.834 -0.92
BXD45 m 7.0028 2.2538   5 1.0079 0.3218 4.264, 9.134 -0.04
BXD48 m 4.4772 2.7057   5 1.21 0.6043 2.11, 8.416 -0.45
BXD48a m 7.297 3.4812   4 1.7406 0.4771 4.418, 11.812 0.01
BXD49 m 7.0035 5.9033   4 2.9516 0.8429 2.25, 14.794 -0.04
BXD51 m 2.1776 1.8314   3 1.0573 0.841 1.054, 4.2909 -0.83
BXD53 m 3.9016 1.5259   5 0.6824 0.3911 1.276, 5.136 -0.55
BXD55 m 9.0244 8.9349   5 3.9958 0.9901 2.266, 24.104 0.29
BXD6 m 10.809 15.063   5 6.7362 1.3936 1.212, 37.438 0.58
BXD62 m 27.439 30.707   4 15.353 1.1191 3.924, 70.47 3.29
BXD63 m 3.3536 1.6057   5 0.71808 0.4788 1.594, 5.824 -0.64
BXD64 m 4.4004 2.914   5 1.3032 0.6622 1.996, 9.476 -0.47
BXD66 m 7.826 8.1056   3 4.6797 1.0357 2.584, 17.162 0.09
BXD67 m 5.5886 4.4794   5 2.0032 0.8015 1.68, 10.772 -0.27
BXD69 m 4.682 3.5466   4 1.7733 0.7575 1.08, 8.5 -0.42
BXD73 m 10.162 11.072   3 6.3924 1.0896 3.64, 22.946 0.47
BXD75 m 6.4295 7.9014   4 3.9507 1.2289 1.724, 18.246 -0.14
BXD77 m 8.3744 2.9522   5 1.3203 0.3525 5.43, 13.162 0.18
BXD79 m 3.8736 2.5883   5 1.1575 0.6682 1.038, 6.956 -0.55
BXD8 m 2.644 1.3859   2   0.98 0.5242 1.664, 3.624 -0.75
BXD81 m 7.3024 3.6564   5 1.6352 0.5007 4.288, 13.484 0.01
BXD84 m 18.108 24.412   4 12.206 1.3481 1.64, 54.09 1.77
BXD87 m 3.471 1.7748   2   1.255 0.5113 2.216, 4.726 -0.62
BXD89 m 3.9464 2.3803   5 1.0645 0.6032 1.756, 7.17 -0.54
BXD90 m 3.5414 1.811   4 0.90549 0.5114 1.8235, 5.818 -0.61
C57BL/6J m 2.0847 0.73722   3 0.42563 0.3536 1.358, 2.832 -0.84
DBA/2J m 1.914 0.0   1   0.0 0.0 1.914, 1.914 -0.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 6.312575 6.0637127793 18.3357973146 -5.7106473146
BXD100 m 2.7376 5.4235495882 13.4914969617 -8.0162969617
BXD11 m 6.07 7.0017724108 19.9532212798 -7.8132212798
BXD12 m 27.284 6.0637127793 39.3072223146 15.2607776854
BXD27 m 15.5715 6.0637127793 27.5947223146 3.5482776854
BXD32 m 4.0045 6.0637127793 16.0277223146 -8.0187223146
BXD34 m 4.7625 6.0637127793 16.7857223146 -7.2607223146
BXD39 m 5.269 8.5753848508 22.2724040608 -11.7344040608
BXD40 m 11.043 6.0637127793 23.0662223146 -0.9802223146
BXD43 m 1.629 8.5753848508 18.6324040608 -15.3744040608
BXD45 m 7.0028 5.4235495882 17.7566969617 -3.7510969617
BXD48 m 4.4772 5.4235495882 15.2310969617 -6.2766969617
BXD48a m 7.297 6.0637127793 19.3202223146 -4.7262223146
BXD49 m 7.0035 6.0637127793 19.0267223146 -5.0197223146
BXD51 m 2.1776333333 7.0017724108 16.0608546131 -11.7055879464
BXD53 m 3.9016 5.4235495882 14.6554969617 -6.8522969617
BXD55 m 9.0244 5.4235495882 19.7782969617 -1.7294969617
BXD6 m 10.80866 5.4235495882 21.5625569617 0.0547630383
BXD62 m 27.439 6.0637127793 39.4622223146 15.4157776854
BXD63 m 3.3536 5.4235495882 14.1074969617 -7.4002969617
BXD64 m 4.4004 5.4235495882 15.1542969617 -6.3534969617
BXD66 m 7.826 7.0017724108 21.7092212798 -6.0572212798
BXD67 m 5.5886 5.4235495882 16.3424969617 -5.1652969617
BXD69 m 4.682 6.0637127793 16.7052223146 -7.3412223146
BXD73 m 10.162 7.0017724108 24.0452212798 -3.7212212798
BXD75 m 6.4295 6.0637127793 18.4527223146 -5.5937223146
BXD77 m 8.3744 5.4235495882 19.1282969617 -2.3794969617
BXD79 m 3.8736 5.4235495882 14.6274969617 -6.8802969617
BXD8 m 2.644 8.5753848508 19.6474040608 -14.3594040608
BXD81 m 7.3024 5.4235495882 18.0562969617 -3.4514969617
BXD84 m 18.10775 6.0637127793 30.1309723146 6.0845276854
BXD87 m 3.471 8.5753848508 20.4744040608 -13.5324040608
BXD89 m 3.9464 5.4235495882 14.7002969617 -6.8074969617
BXD90 m 3.541375 6.0637127793 15.5645973146 -8.4818473146
C57BL/6J m 2.0846666667 7.0017724108 15.9678879464 -11.7985546131




  GWAS USING LINEAR MIXED MODELS