Project measure / variable:   Schoonjans1   keto_DCA_plasma_t30_HFD

ID, description, units MPD:112685   keto_DCA_plasma_t30_HFD   plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   34 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means1.3131   ng/mL
Median of the strain means0.781   ng/mL
SD of the strain means± 1.3481
Coefficient of variation (CV)1.0266
Min–max range of strain means0.218   –   7.1272   ng/mL
Mean sample size per strain3.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 31 254.4489 8.208 0.9468 0.5547
Residuals 75 650.2202 8.6696


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.659 1.7376   5 0.77706 1.0473 0.242, 4.5938 0.26
BXD100 m 0.401 0.25314   2   0.179 0.6313 0.222, 0.58 -0.68
BXD11 m 0.921 0.42285   2   0.299 0.4591 0.622, 1.22 -0.29
BXD12 m 1.1247 1.1563   3 0.66759 1.0281 0.222, 2.428 -0.14
BXD27 m 1.1527 1.1426   3 0.65967 0.9912 0.49, 2.472 -0.12
BXD32 m 0.905 0.30688   2   0.217 0.3391 0.688, 1.122 -0.3
BXD34 m 0.468 0.27393   3 0.15815 0.5853 0.208, 0.754 -0.63
BXD39 m 0.609 0.25597   2   0.181 0.4203 0.428, 0.79 -0.52
BXD40 m 1.553 1.5782   4 0.78911 1.0162 0.382, 3.842 0.18
BXD45 m 0.7048 0.34729   5 0.15531 0.4928 0.352, 1.194 -0.45
BXD48 m 3.033 2.4508   2   1.733 0.8081 1.3, 4.766 1.28
BXD48a m 1.6035 1.0583   4 0.52916 0.66 0.666, 2.736 0.22
BXD49 m 7.1272 9.643   5 4.3125 1.353 0.758, 22.73 4.31
BXD53 m 0.4935 0.37451   4 0.18726 0.7589 0.22, 1.046 -0.61
BXD55 m 2.1608 2.8045   5 1.2542 1.2979 0.376, 7.086 0.63
BXD6 m 4.1538 6.4708   5 2.8938 1.5578 0.25, 15.517 2.11
BXD62 m 2.9567 3.1766   3 1.834 1.0744 0.728, 6.594 1.22
BXD63 m 0.4315 0.31389   4 0.15695 0.7274 0.2, 0.88 -0.65
BXD64 m 0.641 0.15132   2   0.107 0.2361 0.534, 0.748 -0.5
BXD66 m 0.718 0.4978   2   0.352 0.6933 0.366, 1.07 -0.44
BXD67 m 0.61333 0.35487   3 0.20488 0.5786 0.326, 1.01 -0.52
BXD69 m 1.6107 0.8961   3 0.51737 0.5564 0.576, 2.138 0.22
BXD73 m 1.0073 1.0717   3 0.61873 1.0639 0.318, 2.242 -0.23
BXD75 m 2.0713 1.9041   3 1.0993 0.9193 0.97, 4.27 0.56
BXD77 m 0.49 0.39733   5 0.17769 0.8109 0.262, 1.188 -0.61
BXD79 m 0.48933 0.19399   3 0.112 0.3964 0.266, 0.616 -0.61
BXD8 m 0.693 0.02404   2   0.017 0.0347 0.676, 0.71 -0.46
BXD81 m 0.844 0.51617   3 0.29801 0.6116 0.418, 1.418 -0.35
BXD84 m 0.7149 0.44988   5 0.20119 0.6293 0.246, 1.358 -0.44
BXD87 m 0.682 0.56378   3 0.3255 0.8267 0.304, 1.33 -0.47
BXD89 m 1.3235 1.7138   4 0.85688 1.2949 0.266, 3.874 0.01
BXD90 m 0.668 0.0   1   0.0 0.0 0.668, 0.668 -0.48
C57BL/6J m 0.40267 0.09644   3 0.05568 0.2395 0.312, 0.504 -0.68
DBA/2J m 0.218 0.0   1   0.0 0.0 0.218, 0.218 -0.81


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.659026 1.3167841864 4.282194614 -0.964142614
BXD100 m 0.401 2.0820186079 4.5485937535 -3.7465937535
BXD11 m 0.921 2.0820186079 5.0685937535 -3.2265937535
BXD12 m 1.1246666667 1.6999610748 4.5111627855 -2.2618294521
BXD27 m 1.1526666667 1.6999610748 4.5391627855 -2.2338294521
BXD32 m 0.905 2.0820186079 5.0525937535 -3.2425937535
BXD34 m 0.468 1.6999610748 3.8544961188 -2.9184961188
BXD39 m 0.609 2.0820186079 4.7565937535 -3.5385937535
BXD40 m 1.553 1.4722094762 4.4857916687 -1.3797916687
BXD45 m 0.7048 1.3167841864 3.327968614 -1.918368614
BXD48 m 3.033 2.0820186079 7.1805937535 -1.1145937535
BXD48a m 1.6035 1.4722094762 4.5362916687 -1.3292916687
BXD49 m 7.1272 1.3167841864 9.750368614 4.504031386
BXD53 m 0.4935 1.4722094762 3.4262916687 -2.4392916687
BXD55 m 2.1608 1.3167841864 4.783968614 -0.462368614
BXD6 m 4.15378 1.3167841864 6.776948614 1.530611386
BXD62 m 2.9566666667 1.6999610748 6.3431627855 -0.4298294521
BXD63 m 0.4315 1.4722094762 3.3642916687 -2.5012916687
BXD64 m 0.641 2.0820186079 4.7885937535 -3.5065937535
BXD66 m 0.718 2.0820186079 4.8655937535 -3.4295937535
BXD67 m 0.6133333333 1.6999610748 3.9998294521 -2.7731627855
BXD69 m 1.6106666667 1.6999610748 4.9971627855 -1.7758294521
BXD73 m 1.0073333333 1.6999610748 4.3938294521 -2.3791627855
BXD75 m 2.0713333333 1.6999610748 5.4578294521 -1.3151627855
BXD77 m 0.49 1.3167841864 3.113168614 -2.133168614
BXD79 m 0.4893333333 1.6999610748 3.8758294521 -2.8971627855
BXD8 m 0.693 2.0820186079 4.8405937535 -3.4545937535
BXD81 m 0.844 1.6999610748 4.2304961188 -2.5424961188
BXD84 m 0.7149 1.3167841864 3.338068614 -1.908268614
BXD87 m 0.682 1.6999610748 4.0684961188 -2.7044961188
BXD89 m 1.3235 1.4722094762 4.2562916687 -1.6092916687
C57BL/6J m 0.4026666667 1.6999610748 3.7891627855 -2.9838294521




  GWAS USING LINEAR MIXED MODELS