Project measure / variable:   Schoonjans1   keto_DCA_plasma_t30_CD

ID, description, units MPD:112684   keto_DCA_plasma_t30_CD   plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 7-ketodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means8.0409   ng/mL
Median of the strain means1.6939   ng/mL
SD of the strain means± 13.064
Coefficient of variation (CV)1.6247
Min–max range of strain means0.25467   –   50.27   ng/mL
Mean sample size per strain3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 32 26754.8408 836.0888 2.1283 0.0025
Residuals 98 38499.0704 392.8477


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 31.274 61.95   4 30.975 1.9809 0.226, 124.2 1.78
BXD100 m 1.364 0.97626   5 0.4366 0.7157 0.232, 2.902 -0.51
BXD11 m 0.727 0.24749   2   0.175 0.3404 0.552, 0.902 -0.56
BXD12 m 11.437 17.803   3 10.279 1.5567 0.556, 31.982 0.26
BXD27 m 4.1093 5.8528   3 3.3791 1.4243 0.542, 10.864 -0.3
BXD32 m 7.5852 7.4813   5 3.3457 0.9863 1.534, 17.688 -0.03
BXD34 m 3.9724 2.1171   5 0.94679 0.5329 1.37, 7.046 -0.31
BXD39 m 3.576 0.0   1   0.0 0.0 3.576, 3.576 -0.34
BXD40 m 14.752 12.609   4 6.3045 0.8547 1.704, 29.026 0.51
BXD43 m 0.96 0.0   1   0.0 0.0 0.96, 0.96 -0.54
BXD45 m 8.8415 12.916   4 6.4582 1.4609 0.522, 28.012 0.06
BXD48 m 0.8796 0.17725   5 0.07927 0.2015 0.574, 1.004 -0.55
BXD48a m 1.9755 0.82304   4 0.41152 0.4166 1.186, 3.096 -0.46
BXD49 m 42.983 40.325   5 18.034 0.9382 1.798, 94.18 2.67
BXD51 m 0.29867 0.06646   3 0.03837 0.2225 0.222, 0.34 -0.59
BXD53 m 1.799 1.265   4 0.63249 0.7032 0.248, 2.964 -0.48
BXD55 m 50.27 42.183   5 18.865 0.8392 6.828, 95.91 3.23
BXD6 m 41.285 44.603   5 19.947 1.0804 9.674, 112.7 2.54
BXD62 m 0.6204 0.45526   5 0.2036 0.7338 0.244, 1.404 -0.57
BXD63 m 1.295 1.0965   4 0.54824 0.8467 0.304, 2.604 -0.52
BXD64 m 0.25467 0.05139   3 0.02967 0.2018 0.2, 0.302 -0.6
BXD66 m 0.30933 0.07229   3 0.04173 0.2337 0.258, 0.392 -0.59
BXD67 m 0.41333 0.12055   3 0.0696 0.2917 0.3, 0.54 -0.58
BXD69 m 1.5888 1.9533   5 0.87354 1.2294 0.324, 5.036 -0.49
BXD73 m 17.735 28.963   3 16.722 1.633 0.37, 51.17 0.74
BXD75 m 1.0892 1.0141   5 0.45351 0.931 0.454, 2.89 -0.53
BXD77 m 4.4252 5.4096   5 2.4192 1.2225 0.67, 13.584 -0.28
BXD79 m 0.9944 1.3997   5 0.62598 1.4076 0.232, 3.466 -0.54
BXD8 m 0.412 0.09051   2   0.064 0.2197 0.348, 0.476 -0.58
BXD81 m 4.371 6.7332   3 3.8874 1.5404 0.226, 12.14 -0.28
BXD84 m 0.318 0.14208   3 0.08203 0.4468 0.232, 0.482 -0.59
BXD87 m 9.2792 8.9273   5 3.9924 0.9621 3.196, 25.008 0.09
BXD89 m 1.0127 1.1411   3 0.65882 1.1268 0.23, 2.322 -0.54
BXD90 m 0.75 0.0   1   0.0 0.0 0.75, 0.75 -0.56
C57BL/6J m 15.963 17.567   5 7.8562 1.1005 2.868, 45.756 0.61
DBA/2J m 0.55267 0.26187   3 0.15119 0.4738 0.304, 0.826 -0.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 31.274 9.9101924463 50.9404543776 11.6075456224
BXD100 m 1.364 8.863945592 18.9542115459 -16.2262115459
BXD11 m 0.727 14.0151285633 28.5395665046 -27.0855665046
BXD12 m 11.4366666667 11.4433045532 34.1455321245 -11.2721987912
BXD27 m 4.1093333333 11.4433045532 26.8181987912 -18.5995321245
BXD32 m 7.5852 8.863945592 25.1754115459 -10.0050115459
BXD34 m 3.9724 8.863945592 21.5626115459 -13.6178115459
BXD40 m 14.752 9.9101924463 34.4184543776 -4.9144543776
BXD45 m 8.8415 9.9101924463 28.5079543776 -10.8249543776
BXD48 m 0.8796 8.863945592 18.4698115459 -16.7106115459
BXD48a m 1.9755 9.9101924463 21.6419543776 -17.6909543776
BXD49 m 42.9832 8.863945592 60.5734115459 25.3929884541
BXD51 m 0.2986666667 11.4433045532 23.0075321245 -22.4101987912
BXD53 m 1.799 9.9101924463 21.4654543776 -17.8674543776
BXD55 m 50.2656 8.863945592 67.8558115459 32.6753884541
BXD6 m 41.2848 8.863945592 58.8750115459 23.6945884541
BXD62 m 0.6204 8.863945592 18.2106115459 -16.9698115459
BXD63 m 1.295 9.9101924463 20.9614543776 -18.3714543776
BXD64 m 0.2546666667 11.4433045532 22.9635321245 -22.4541987912
BXD66 m 0.3093333333 11.4433045532 23.0181987912 -22.3995321245
BXD67 m 0.4133333333 11.4433045532 23.1221987912 -22.2955321245
BXD69 m 1.5888 8.863945592 19.1790115459 -16.0014115459
BXD73 m 17.7353333333 11.4433045532 40.4441987912 -4.9735321245
BXD75 m 1.0892 8.863945592 18.6794115459 -16.5010115459
BXD77 m 4.4252 8.863945592 22.0154115459 -13.1650115459
BXD79 m 0.9944 8.863945592 18.5846115459 -16.5958115459
BXD8 m 0.412 14.0151285633 28.2245665046 -27.4005665046
BXD81 m 4.3709566667 11.4433045532 27.0798221245 -18.3379087912
BXD84 m 0.318 11.4433045532 23.0268654579 -22.3908654579
BXD87 m 9.2792 8.863945592 26.8694115459 -8.3110115459
BXD89 m 1.0126666667 11.4433045532 23.7215321245 -21.6961987912
C57BL/6J m 15.9628 8.863945592 33.5530115459 -1.6274115459
DBA/2J m 0.5526666667 11.4433045532 23.2615321245 -22.1561987912




  GWAS USING LINEAR MIXED MODELS