Project measure / variable:   Schoonjans1   oxo_CA_plasma_t30_CD

ID, description, units MPD:112682   oxo_CA_plasma_t30_CD   plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   15 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means6.9601   ng/mL
Median of the strain means5.7635   ng/mL
SD of the strain means± 5.0215
Coefficient of variation (CV)0.7215
Min–max range of strain means2.628   –   19.784   ng/mL
Mean sample size per strain1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 42.322 6.046 0.5497 0.7836
Residuals 14 153.98 10.9986


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 19.784 0.0   1   0.0 0.0 19.784, 19.784 2.55
BXD12 m 3.202 0.0   1   0.0 0.0 3.202, 3.202 -0.75
BXD27 m 3.24 0.0   1   0.0 0.0 3.24, 3.24 -0.74
BXD32 m 6.8987 3.3979   3 1.9618 0.4925 3.0, 9.23 -0.01
BXD34 m 3.351 0.53882   2   0.381 0.1608 2.97, 3.732 -0.72
BXD40 m 7.4347 3.954   3 2.2828 0.5318 3.056, 10.744 0.09
BXD45 m 3.67 0.0   1   0.0 0.0 3.67, 3.67 -0.66
BXD49 m 3.881 1.3675   2   0.967 0.3524 2.914, 4.848 -0.61
BXD55 m 5.7635 3.2015   4 1.6008 0.5555 2.95, 9.19 -0.24
BXD6 m 7.7473 3.8937   3 2.248 0.5026 3.508, 11.164 0.16
BXD73 m 16.878 0.0   1   0.0 0.0 16.878, 16.878 1.98
BXD77 m 8.85 0.0   1   0.0 0.0 8.85, 8.85 0.38
BXD81 m 2.628 0.0   1   0.0 0.0 2.628, 2.628 -0.86
BXD87 m 5.8727 4.0489   3 2.3376 0.6894 3.252, 10.536 -0.22
C57BL/6J m 5.2 1.8979   2   1.342 0.365 3.858, 6.542 -0.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD32 m 6.8986666667 1.9147297314 11.0053535056 2.7919798277
BXD34 m 3.351 2.3450554187 8.3806436444 -1.6786436444
BXD40 m 7.4346666667 1.9147297314 11.5413535056 3.3279798277
BXD49 m 3.881 2.3450554187 8.9106436444 -1.1486436444
BXD55 m 5.7635 1.6582045888 9.3199951279 2.2070048721
BXD6 m 7.7473333333 1.9147297314 11.8540201723 3.6406464944
BXD87 m 5.8726666667 1.9147297314 9.9793535056 1.7659798277
C57BL/6J m 5.2 2.3450554187 10.2296436444 0.1703563556




  GWAS USING LINEAR MIXED MODELS