Project measure / variable:   Schoonjans1   wMCA_plasma_t0_HFD

ID, description, units MPD:112681   wMCA_plasma_t0_HFD   plasma bile acid ω-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ω-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means48.985   ng/mL
Median of the strain means38.811   ng/mL
SD of the strain means± 37.007
Coefficient of variation (CV)0.7555
Min–max range of strain means6.3733   –   171.4   ng/mL
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 193899.2785 5539.9794 2.3996 0.0002
Residuals 120 277039.8173 2308.6651


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 10.49 1.8441   5 0.82468 0.1758 8.154, 12.761 -1.04
BXD100 m 14.216 9.9549   9 3.3183 0.7002 4.988, 34.126 -0.94
BXD11 m 72.0 65.2   3 37.645 0.9056 31.176, 147.2 0.62
BXD12 m 171.4 217.0   3 125.3 1.2656 29.954, 421.2 3.31
BXD27 m 19.654 24.567   5 10.987 1.25 2.986, 63.19 -0.79
BXD32 m 17.556 5.4694   4 2.7347 0.3115 9.74, 22.064 -0.85
BXD34 m 46.081 36.681   4 18.34 0.796 21.782, 100.4 -0.08
BXD39 m 36.433 18.516   3 10.69 0.5082 21.116, 57.01 -0.34
BXD40 m 103.0 36.162   4 18.081 0.3511 61.32, 142.0 1.46
BXD43 m 16.528 8.1163   5 3.6297 0.4911 8.144, 29.342 -0.88
BXD45 m 63.12 10.05   5 4.4947 0.1592 57.0, 81.01 0.38
BXD48 m 40.157 11.717   5 5.2402 0.2918 30.514, 58.97 -0.24
BXD48a m 43.923 16.464   4 8.2319 0.3748 19.642, 56.15 -0.14
BXD49 m 108.2 94.04   5 42.055 0.8688 35.19, 271.3 1.6
BXD51 m 15.529 8.0248   3 4.6331 0.5168 8.592, 24.318 -0.9
BXD53 m 90.66 34.116   5 15.257 0.3763 53.98, 126.8 1.13
BXD55 m 36.545 33.373   5 14.925 0.9132 7.268, 87.71 -0.34
BXD6 m 121.4 120.7   5 53.98 0.9944 13.503, 324.8 1.96
BXD62 m 26.169 19.251   4 9.6257 0.7356 14.458, 54.83 -0.62
BXD63 m 23.465 11.911   5 5.3268 0.5076 12.676, 42.632 -0.69
BXD64 m 62.69 31.47   5 14.074 0.502 23.89, 103.6 0.37
BXD66 m 92.95 37.589   3 21.702 0.4044 59.27, 133.5 1.19
BXD67 m 47.643 12.54   5 5.608 0.2632 28.422, 60.33 -0.04
BXD69 m 15.587 14.219   4 7.1093 0.9122 4.312, 35.374 -0.9
BXD73 m 60.43 50.53   3 29.173 0.8362 26.512, 118.5 0.31
BXD75 m 15.096 10.041   4 5.0205 0.6652 3.83, 27.876 -0.92
BXD77 m 60.04 21.512   5 9.6204 0.3583 40.634, 94.99 0.3
BXD79 m 33.968 15.704   5 7.0231 0.4623 8.476, 49.656 -0.41
BXD8 m 32.047 33.832   2   23.923 1.0557 8.124, 55.97 -0.46
BXD81 m 42.322 15.081   5 6.7446 0.3563 26.452, 65.24 -0.18
BXD84 m 37.465 27.423   5 12.264 0.732 12.676, 68.98 -0.31
BXD87 m 19.503 17.309   4 8.6543 0.8875 3.554, 41.228 -0.8
BXD89 m 92.64 89.28   5 39.925 0.9637 25.534, 246.5 1.18
BXD90 m 25.681 19.975   4 9.9876 0.7778 11.69, 54.59 -0.63
C57BL/6J m 42.491 16.295   3 9.4081 0.3835 29.776, 60.86 -0.18
DBA/2J m 6.3733 2.9421   3 1.6986 0.4616 3.06, 8.68 -1.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 10.4898 21.4879740504 53.0344931659 -32.0548931659
BXD100 m 14.2162222222 16.0161902251 45.9271642225 -17.4947197781
BXD11 m 72.002 27.7408552136 126.9269627004 17.0770372996
BXD12 m 171.418 27.7408552136 226.3429627004 116.4930372996
BXD27 m 19.654 21.4879740504 62.1986931659 -22.8906931659
BXD32 m 17.556 24.0242853377 65.1224130005 -30.0104130005
BXD34 m 46.0805 24.0242853377 93.6469130005 -1.4859130005
BXD39 m 36.4326666667 27.7408552136 91.3576293671 -18.4922960337
BXD40 m 102.9875 24.0242853377 150.5539130005 55.4210869995
BXD43 m 16.5276 21.4879740504 59.0722931659 -26.0170931659
BXD45 m 63.122 21.4879740504 105.6666931659 20.5773068341
BXD48 m 40.1568 21.4879740504 82.7014931659 -2.3878931659
BXD48a m 43.923 24.0242853377 91.4894130005 -3.6434130005
BXD49 m 108.24 21.4879740504 150.7846931659 65.6953068341
BXD51 m 15.5293333333 27.7408552136 70.4542960337 -39.3956293671
BXD53 m 90.656 21.4879740504 133.2006931659 48.1113068341
BXD55 m 36.5452 21.4879740504 79.0898931659 -5.9994931659
BXD6 m 121.3786 21.4879740504 163.9232931659 78.8339068341
BXD62 m 26.1695 24.0242853377 73.7359130005 -21.3969130005
BXD63 m 23.4652 21.4879740504 66.0098931659 -19.0794931659
BXD64 m 62.6856 21.4879740504 105.2302931659 20.1409068341
BXD66 m 92.95 27.7408552136 147.8749627004 38.0250372996
BXD67 m 47.6428 21.4879740504 90.1874931659 5.0981068341
BXD69 m 15.5865 24.0242853377 63.1529130005 -31.9799130005
BXD73 m 60.4273333333 27.7408552136 115.3522960337 5.5023706329
BXD75 m 15.0955 24.0242853377 62.6619130005 -32.4709130005
BXD77 m 60.0388 21.4879740504 102.5834931659 17.4941068341
BXD79 m 33.968 21.4879740504 76.5126931659 -8.5766931659
BXD8 m 32.047 33.9754701509 99.3160663787 -35.2220663787
BXD81 m 42.3224 21.4879740504 84.8670931659 -0.2222931659
BXD84 m 37.4652 21.4879740504 80.0098931659 -5.0794931659
BXD87 m 19.5025 24.0242853377 67.0689130005 -28.0639130005
BXD89 m 92.6396 21.4879740504 135.1842931659 50.0949068341
BXD90 m 25.6815 24.0242853377 73.2479130005 -21.8849130005
C57BL/6J m 42.4906666667 27.7408552136 97.4156293671 -12.4342960337
DBA/2J m 6.3733333333 27.7408552136 61.2982960337 -48.5516293671




  GWAS USING LINEAR MIXED MODELS