Project measure / variable:   Schoonjans1   UDCA_plasma_t0_HFD

ID, description, units MPD:112679   UDCA_plasma_t0_HFD   plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   32 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested32 strains
Mean of the strain means5.845   ng/mL
Median of the strain means4.6071   ng/mL
SD of the strain means± 4.2362
Coefficient of variation (CV)0.7247
Min–max range of strain means1.752   –   20.379   ng/mL
Mean sample size per strain2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 23 1440.0205 62.6096 0.9754 0.5106
Residuals 48 3081.0765 64.1891


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD100 m 1.752 0.0   1   0.0 0.0 1.752, 1.752 -0.97
BXD11 m 4.024 2.7521   2   1.946 0.6839 2.078, 5.97 -0.43
BXD12 m 3.754 2.8652   2   2.026 0.7632 1.728, 5.78 -0.49
BXD27 m 13.387 18.692   3 10.792 1.3963 1.612, 34.94 1.78
BXD32 m 5.957 1.4496   2   1.025 0.2433 4.932, 6.982 0.03
BXD34 m 4.917 4.2129   2   2.979 0.8568 1.938, 7.896 -0.22
BXD39 m 8.697 10.574   2   7.477 1.2158 1.22, 16.174 0.67
BXD40 m 6.403 6.3122   4 3.1561 0.9858 1.282, 15.014 0.13
BXD45 m 4.6868 2.117   5 0.94676 0.4517 2.81, 7.244 -0.27
BXD48 m 5.658 0.0   1   0.0 0.0 5.658, 5.658 -0.04
BXD48a m 2.199 0.74812   2   0.529 0.3402 1.67, 2.728 -0.86
BXD49 m 20.379 21.386   4 10.693 1.0494 2.302, 49.128 3.43
BXD53 m 4.328 0.0   1   0.0 0.0 4.328, 4.328 -0.36
BXD55 m 8.5585 8.5319   4 4.266 0.9969 1.46, 20.746 0.64
BXD6 m 7.3376 6.7285   4 3.3643 0.917 1.668, 16.633 0.35
BXD62 m 1.9333 0.86835   3 0.50134 0.4491 1.378, 2.934 -0.92
BXD63 m 2.795 1.9389   2   1.371 0.6937 1.424, 4.166 -0.72
BXD64 m 4.0593 3.959   3 2.2858 0.9753 1.278, 8.592 -0.42
BXD66 m 2.312 0.0   1   0.0 0.0 2.312, 2.312 -0.83
BXD67 m 2.2545 0.77915   4 0.38957 0.3456 1.402, 3.07 -0.85
BXD69 m 6.262 5.8888   2   4.164 0.9404 2.098, 10.426 0.1
BXD73 m 4.5273 3.5544   3 2.0521 0.7851 1.438, 8.412 -0.31
BXD75 m 14.748 0.0   1   0.0 0.0 14.748, 14.748 2.1
BXD77 m 4.881 3.4054   4 1.7027 0.6977 2.736, 9.966 -0.23
BXD79 m 1.9433 1.0259   3 0.59228 0.5279 1.212, 3.116 -0.92
BXD8 m 11.202 0.0   1   0.0 0.0 11.202, 11.202 1.26
BXD81 m 1.906 0.28625   4 0.14312 0.1502 1.502, 2.146 -0.93
BXD84 m 4.104 0.56851   2   0.402 0.1385 3.702, 4.506 -0.41
BXD87 m 6.012 0.0   1   0.0 0.0 6.012, 6.012 0.04
BXD89 m 9.773 8.8445   4 4.4223 0.905 4.022, 22.726 0.93
BXD90 m 3.355 0.21355   2   0.151 0.0637 3.204, 3.506 -0.59
C57BL/6J m 2.936 0.0   1   0.0 0.0 2.936, 2.936 -0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD11 m 4.024 5.6652048873 15.4146578554 -7.3666578554
BXD12 m 3.754 5.6652048873 15.1446578554 -7.6366578554
BXD27 m 13.3866666667 4.6256204207 22.6870998601 4.0862334732
BXD32 m 5.957 5.6652048873 17.3476578554 -5.4336578554
BXD34 m 4.917 5.6652048873 16.3076578554 -6.4736578554
BXD39 m 8.697 5.6652048873 20.0876578554 -2.6936578554
BXD40 m 6.403 4.0059047926 14.4574114117 -1.6514114117
BXD45 m 4.6868 3.5829901711 11.8908845742 -2.5172845742
BXD48a m 2.199 5.6652048873 13.5896578554 -9.1916578554
BXD49 m 20.3785 4.0059047926 28.4329114117 12.3240885883
BXD55 m 8.5585 4.0059047926 16.6129114117 0.5040885883
BXD6 m 7.337625 4.0059047926 15.3920364117 -0.7167864117
BXD62 m 1.9333333333 4.6256204207 11.2337665268 -7.3670998601
BXD63 m 2.795 5.6652048873 14.1856578554 -8.5956578554
BXD64 m 4.0593333333 4.6256204207 13.3597665268 -5.2410998601
BXD67 m 2.2545 4.0059047926 10.3089114117 -5.7999114117
BXD69 m 6.262 5.6652048873 17.6526578554 -5.1286578554
BXD73 m 4.5273333333 4.6256204207 13.8277665268 -4.7730998601
BXD77 m 4.881 4.0059047926 12.9354114117 -3.1734114117
BXD79 m 1.9433333333 4.6256204207 11.2437665268 -7.3570998601
BXD81 m 1.906 4.0059047926 9.9604114117 -6.1484114117
BXD84 m 4.104 5.6652048873 15.4946578554 -7.2866578554
BXD89 m 9.773 4.0059047926 17.8274114117 1.7185885883
BXD90 m 3.355 5.6652048873 14.7456578554 -8.0356578554




  GWAS USING LINEAR MIXED MODELS