Project measure / variable:   Schoonjans1   UDCA_plasma_t0_CD

ID, description, units MPD:112678   UDCA_plasma_t0_CD   plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   28 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested28 strains
Mean of the strain means12.799   ng/mL
Median of the strain means9.044   ng/mL
SD of the strain means± 14.068
Coefficient of variation (CV)1.0991
Min–max range of strain means1.3647   –   58.67   ng/mL
Mean sample size per strain2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 17 12261.1947 721.2467 1.6886 0.0843
Residuals 42 17938.9102 427.1169


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 58.67 0.0   1   0.0 0.0 58.67, 58.67 3.26
BXD11 m 1.4267 0.18102   3 0.10451 0.1269 1.3, 1.634 -0.81
BXD12 m 7.6 0.0   1   0.0 0.0 7.6, 7.6 -0.37
BXD27 m 9.98 0.0   1   0.0 0.0 9.98, 9.98 -0.2
BXD32 m 20.699 21.314   2   15.071 1.0297 5.628, 35.77 0.56
BXD34 m 6.1045 3.604   4 1.802 0.5904 1.946, 9.462 -0.48
BXD39 m 8.702 0.0   1   0.0 0.0 8.702, 8.702 -0.29
BXD40 m 11.835 7.5399   4 3.77 0.6371 1.556, 18.642 -0.07
BXD43 m 5.26 0.0   1   0.0 0.0 5.26, 5.26 -0.54
BXD45 m 27.074 34.43   2   24.346 1.2717 2.728, 51.42 1.01
BXD48 m 6.4207 3.5877   3 2.0713 0.5588 3.106, 10.23 -0.45
BXD48a m 1.987 0.5869   2   0.415 0.2954 1.572, 2.402 -0.77
BXD49 m 15.912 12.171   4 6.0857 0.7649 1.636, 28.978 0.22
BXD53 m 11.312 0.0   1   0.0 0.0 11.312, 11.312 -0.11
BXD55 m 7.337 8.0398   4 4.0199 1.0958 1.426, 18.876 -0.39
BXD6 m 55.22 57.49   5 25.708 1.041 8.24, 123.6 3.02
BXD62 m 3.158 0.0   1   0.0 0.0 3.158, 3.158 -0.69
BXD64 m 1.3647 0.14687   3 0.08479 0.1076 1.272, 1.534 -0.81
BXD73 m 24.046 25.789   3 14.889 1.0725 2.402, 52.58 0.8
BXD75 m 3.4159 1.565   4 0.78249 0.4581 1.78, 5.324 -0.67
BXD77 m 8.498 6.7308   4 3.3654 0.7921 4.122, 18.474 -0.31
BXD79 m 1.739 0.74529   2   0.527 0.4286 1.212, 2.266 -0.79
BXD81 m 10.5 0.0   1   0.0 0.0 10.5, 10.5 -0.16
BXD87 m 9.558 10.709   5 4.7891 1.1204 2.578, 27.992 -0.23
BXD89 m 4.115 0.6067   2   0.429 0.1474 3.686, 4.544 -0.62
BXD90 m 9.386 0.0   1   0.0 0.0 9.386, 9.386 -0.24
C57BL/6J m 15.447 9.553   4 4.7765 0.6184 2.408, 24.772 0.19
DBA/2J m 11.61 0.0   1   0.0 0.0 11.61, 11.61 -0.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD11 m 1.4266666667 11.9319865424 25.5063903861 -22.6530570527
BXD32 m 20.699 14.6136393233 50.1905181299 -8.7925181299
BXD34 m 6.1045 10.3334034633 26.9581524571 -14.7491524571
BXD40 m 11.835 10.3334034633 32.6886524571 -9.0186524571
BXD45 m 27.074 14.6136393233 56.5655181299 -2.4175181299
BXD48 m 6.4206666667 11.9319865424 30.5003903861 -17.6590570527
BXD48a m 1.987 14.6136393233 31.4785181299 -27.5045181299
BXD49 m 15.912 10.3334034633 36.7656524571 -4.9416524571
BXD55 m 7.337 10.3334034633 28.1906524571 -13.5166524571
BXD6 m 55.2212 9.2424770331 73.8732737893 36.5691262107
BXD64 m 1.3646666667 11.9319865424 25.4443903861 -22.7150570527
BXD73 m 24.046 11.9319865424 48.1257237194 -0.0337237194
BXD75 m 3.4159 10.3334034633 24.2695524571 -17.4377524571
BXD77 m 8.498 10.3334034633 29.3516524571 -12.3556524571
BXD79 m 1.739 14.6136393233 31.2305181299 -27.7525181299
BXD87 m 9.558 9.2424770331 28.2100737893 -9.0940737893
BXD89 m 4.115 14.6136393233 33.6065181299 -25.3765181299
C57BL/6J m 15.447 10.3334034633 36.3006524571 -5.4066524571




  GWAS USING LINEAR MIXED MODELS