Project measure / variable:   Schoonjans1   TUDCA_plasma_t0_HFD

ID, description, units MPD:112677   TUDCA_plasma_t0_HFD   plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauroursodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means33.672   ng/mL
Median of the strain means29.714   ng/mL
SD of the strain means± 21.604
Coefficient of variation (CV)0.6416
Min–max range of strain means5.688   –   90.09   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 72663.3187 2076.0948 4.3516 < 0.0001
Residuals 121 57728.1523 477.0922


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 8.9232 2.7776   5 1.2422 0.3113 6.05, 13.196 -1.15
BXD100 m 13.589 10.124   9 3.3747 0.745 2.856, 30.266 -0.93
BXD11 m 52.14 21.002   3 12.125 0.4028 27.906, 65.13 0.85
BXD12 m 46.638 14.066   3 8.121 0.3016 37.55, 62.84 0.6
BXD27 m 25.59 14.839   5 6.6362 0.5799 7.988, 48.124 -0.37
BXD32 m 6.4625 3.2676   4 1.6338 0.5056 2.16, 9.564 -1.26
BXD34 m 27.224 7.3525   4 3.6762 0.2701 19.798, 36.57 -0.3
BXD39 m 34.448 30.528   3 17.625 0.8862 15.248, 69.65 0.04
BXD40 m 66.43 3.8127   4 1.9063 0.0574 63.34, 71.59 1.52
BXD43 m 14.588 4.127   5 1.8457 0.2829 10.516, 21.526 -0.88
BXD45 m 77.37 36.133   5 16.159 0.467 30.99, 120.0 2.02
BXD48 m 43.386 5.4835   5 2.4523 0.1264 36.486, 49.132 0.45
BXD48a m 90.09 49.751   4 24.875 0.5522 49.362, 158.3 2.61
BXD49 m 80.12 45.089   5 20.164 0.5628 54.03, 160.1 2.15
BXD51 m 50.43 17.254   3 9.9613 0.3421 31.63, 65.54 0.78
BXD53 m 53.76 18.203   5 8.1406 0.3386 36.322, 73.71 0.93
BXD55 m 29.326 7.4121   5 3.3148 0.2527 19.148, 39.596 -0.2
BXD6 m 51.19 75.97   5 33.974 1.484 3.976, 186.2 0.81
BXD62 m 34.819 4.1748   4 2.0874 0.1199 30.798, 39.998 0.05
BXD63 m 17.23 1.746   5 0.78082 0.1013 14.656, 19.318 -0.76
BXD64 m 13.674 13.979   5 6.2517 1.0223 3.586, 37.946 -0.93
BXD66 m 32.027 14.038   3 8.1048 0.4383 22.816, 48.184 -0.08
BXD67 m 11.979 7.7209   5 3.4529 0.6445 6.494, 24.354 -1.0
BXD69 m 19.882 4.4853   4 2.2427 0.2256 16.598, 26.5 -0.64
BXD73 m 6.334 2.1725   3 1.2543 0.343 3.924, 8.142 -1.27
BXD75 m 41.266 15.277   4 7.6384 0.3702 22.036, 53.68 0.35
BXD77 m 13.63 15.338   5 6.8591 1.1253 2.708, 40.466 -0.93
BXD79 m 25.668 9.2549   5 4.1389 0.3606 15.714, 38.864 -0.37
BXD8 m 27.944 11.421   3 6.594 0.4087 16.966, 39.762 -0.27
BXD81 m 19.629 14.947   5 6.6847 0.7615 11.444, 46.314 -0.65
BXD84 m 30.102 13.128   5 5.8708 0.4361 20.062, 50.24 -0.17
BXD87 m 15.221 4.6984   4 2.3492 0.3087 9.628, 20.654 -0.85
BXD89 m 41.417 5.9057   5 2.6411 0.1426 33.352, 49.946 0.36
BXD90 m 42.002 8.0899   4 4.045 0.1926 34.608, 53.27 0.39
C57BL/6J m 41.977 17.875   3 10.32 0.4258 26.032, 61.3 0.38
DBA/2J m 5.688 1.8273   3 1.055 0.3213 3.604, 7.016 -1.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 8.9232 9.768235953 28.2619995633 -10.4155995633
BXD100 m 13.5888888889 7.2808132037 28.0031790311 -0.8254012533
BXD11 m 52.1353333333 12.6107383892 77.1016162147 27.169050452
BXD12 m 46.638 12.6107383892 71.6042828814 21.6717171186
BXD27 m 25.5896 9.768235953 44.9283995633 6.2508004367
BXD32 m 6.4625 10.9212198055 28.0839352133 -15.1589352133
BXD34 m 27.2245 10.9212198055 48.8459352133 5.6030647867
BXD39 m 34.448 12.6107383892 59.4142828814 9.4817171186
BXD40 m 66.4325 10.9212198055 88.0539352133 44.8110647867
BXD43 m 14.588 9.768235953 33.9267995633 -4.7507995633
BXD45 m 77.37 9.768235953 96.7087995633 58.0312004367
BXD48 m 43.3856 9.768235953 62.7243995633 24.0468004367
BXD48a m 90.088 10.9212198055 111.7094352133 68.4665647867
BXD49 m 80.12 9.768235953 99.4587995633 60.7812004367
BXD51 m 50.43 12.6107383892 75.3962828814 25.4637171186
BXD53 m 53.7634 9.768235953 73.1021995633 34.4246004367
BXD55 m 29.3264 9.768235953 48.6651995633 9.9876004367
BXD6 m 51.1896 9.768235953 70.5283995633 31.8508004367
BXD62 m 34.8195 10.9212198055 56.4409352133 13.1980647867
BXD63 m 17.2304 9.768235953 36.5691995633 -2.1083995633
BXD64 m 13.674 9.768235953 33.0127995633 -5.6647995633
BXD66 m 32.0273333333 12.6107383892 56.9936162147 7.061050452
BXD67 m 11.9788 9.768235953 31.3175995633 -7.3599995633
BXD69 m 19.882 10.9212198055 41.5034352133 -1.7394352133
BXD73 m 6.334 12.6107383892 31.3002828814 -18.6322828814
BXD75 m 41.2655 10.9212198055 62.8869352133 19.6440647867
BXD77 m 13.6296 9.768235953 32.9683995633 -5.7091995633
BXD79 m 25.6676 9.768235953 45.0063995633 6.3288004367
BXD8 m 27.944 12.6107383892 52.9102828814 2.9777171186
BXD81 m 19.6292 9.768235953 38.9679995633 0.2904004367
BXD84 m 30.102 9.768235953 49.4407995633 10.7632004367
BXD87 m 15.221 10.9212198055 36.8424352133 -6.4004352133
BXD89 m 41.4168 9.768235953 60.7555995633 22.0780004367
BXD90 m 42.0015 10.9212198055 63.6229352133 20.3800647867
C57BL/6J m 41.9773333333 12.6107383892 66.9436162147 17.011050452
DBA/2J m 5.688 12.6107383892 30.6542828814 -19.2782828814




  GWAS USING LINEAR MIXED MODELS