Project measure / variable:   Schoonjans1   TDCA_plasma_t0_HFD

ID, description, units MPD:112673   TDCA_plasma_t0_HFD   plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means46.819   ng/mL
Median of the strain means32.046   ng/mL
SD of the strain means± 49.583
Coefficient of variation (CV)1.059
Min–max range of strain means10.585   –   281.1   ng/mL
Mean sample size per strain4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 401612.0632 11812.1195 4.7015 < 0.0001
Residuals 113 283905.6094 2512.439


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 31.534 7.957   5 3.5585 0.2523 23.444, 42.768 -0.31
BXD100 m 14.217 18.418   9 6.1393 1.2955 1.194, 59.3 -0.66
BXD11 m 41.436 0.0   1   0.0 0.0 41.436, 41.436 -0.11
BXD12 m 35.074 21.06   3 12.159 0.6005 13.382, 55.44 -0.24
BXD27 m 25.664 28.803   5 12.881 1.1223 5.018, 75.82 -0.43
BXD32 m 18.696 12.315   4 6.1575 0.6587 4.106, 33.72 -0.57
BXD34 m 11.751 11.496   4 5.7481 0.9783 3.324, 28.648 -0.71
BXD39 m 89.51 132.2   3 76.3 1.4765 11.614, 242.1 0.86
BXD40 m 19.131 4.8673   4 2.4337 0.2544 14.978, 25.81 -0.56
BXD43 m 11.52 8.0098   5 3.5821 0.6953 3.688, 20.172 -0.71
BXD45 m 12.084 4.1984   5 1.8776 0.3474 7.15, 17.904 -0.7
BXD48 m 83.83 45.216   5 20.221 0.5394 45.202, 162.1 0.75
BXD48a m 127.9 104.4   4 52.22 0.8169 27.364, 258.0 1.64
BXD49 m 60.32 55.5   5 24.821 0.92 16.774, 154.2 0.27
BXD51 m 61.26 20.823   3 12.022 0.3399 41.25, 82.81 0.29
BXD53 m 73.85 97.73   5 43.705 1.3233 21.896, 247.8 0.55
BXD55 m 12.112 3.4243   5 1.5314 0.2827 9.546, 17.724 -0.7
BXD6 m 55.27 74.45   3 42.986 1.3472 3.54, 140.6 0.17
BXD62 m 17.367 12.854   4 6.4272 0.7402 9.906, 36.616 -0.59
BXD63 m 281.1 138.4   5 61.88 0.4922 68.88, 410.3 4.73
BXD64 m 11.783 11.17   3 6.449 0.948 1.816, 23.856 -0.71
BXD66 m 17.856 11.883   3 6.8609 0.6655 5.8, 29.559 -0.58
BXD67 m 32.558 23.388   5 10.46 0.7184 13.186, 69.8 -0.29
BXD69 m 29.889 15.987   4 7.9933 0.5349 14.734, 52.46 -0.34
BXD73 m 10.585 7.525   2   5.321 0.7109 5.264, 15.906 -0.73
BXD75 m 83.87 47.218   4 23.609 0.563 25.952, 141.3 0.75
BXD77 m 25.639 26.254   5 11.741 1.024 8.034, 71.88 -0.43
BXD79 m 44.976 36.188   5 16.184 0.8046 9.604, 103.6 -0.04
BXD8 m 16.137 9.9349   2   7.025 0.6157 9.112, 23.162 -0.62
BXD81 m 33.647 20.854   5 9.3262 0.6198 22.218, 70.86 -0.27
BXD84 m 78.06 65.83   5 29.441 0.8433 38.202, 193.8 0.63
BXD87 m 42.584 47.374   4 23.687 1.1125 4.49, 106.9 -0.09
BXD89 m 33.862 17.321   5 7.7464 0.5115 13.176, 57.99 -0.26
BXD90 m 22.37 17.357   4 8.6786 0.7759 7.374, 42.086 -0.49
C57BL/6J m 91.51 80.57   3 46.515 0.8804 34.624, 183.7 0.9
DBA/2J m 26.523 20.287   3 11.713 0.7649 14.33, 49.942 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 31.5336 22.4162397427 75.9442139101 -12.8770139101
BXD100 m 14.2168888889 16.7080786215 47.3186060974 -18.8848283196
BXD12 m 35.074 28.9392410693 92.4078560229 -22.2598560229
BXD27 m 25.6636 22.4162397427 70.0742139101 -18.7470139101
BXD32 m 18.6955 25.0621179323 68.3480758127 -30.9570758128
BXD34 m 11.751 25.0621179323 61.4035758128 -37.9015758128
BXD39 m 89.506 28.9392410693 146.8398560229 32.1721439771
BXD40 m 19.1305 25.0621179323 68.7830758127 -30.5220758127
BXD43 m 11.5196 22.4162397427 55.9302139101 -32.8910139101
BXD45 m 12.0836 22.4162397427 56.4942139101 -32.3270139101
BXD48 m 83.8284 22.4162397427 128.2390139101 39.4177860899
BXD48a m 127.8635 25.0621179323 177.5160758128 78.2109241872
BXD49 m 60.3248 22.4162397427 104.7354139101 15.9141860899
BXD51 m 61.26 28.9392410693 118.5938560229 3.9261439771
BXD53 m 73.8508 22.4162397427 118.2614139101 29.4401860899
BXD55 m 12.1124 22.4162397427 56.5230139101 -32.2982139101
BXD6 m 55.266 28.9392410693 112.5998560229 -2.0678560229
BXD62 m 17.3665 25.0621179323 67.0190758128 -32.2860758128
BXD63 m 281.136 22.4162397427 325.5466139101 236.7253860899
BXD64 m 11.7826666667 28.9392410693 69.1165226896 -45.5511893562
BXD66 m 17.8556666667 28.9392410693 75.1895226896 -39.4781893562
BXD67 m 32.5576 22.4162397427 76.9682139101 -11.8530139101
BXD69 m 29.8885 25.0621179323 79.5410758128 -19.7640758128
BXD73 m 10.585 35.4431870816 80.8043461211 -59.6343461211
BXD75 m 83.8655 25.0621179323 133.5180758127 34.2129241872
BXD77 m 25.6388 22.4162397427 70.0494139101 -18.7718139101
BXD79 m 44.976 22.4162397427 89.3866139101 0.5653860899
BXD8 m 16.137 35.4431870816 86.3563461211 -54.0823461211
BXD81 m 33.6468 22.4162397427 78.0574139101 -10.7638139101
BXD84 m 78.0592 22.4162397427 122.4698139101 33.6485860899
BXD87 m 42.584 25.0621179323 92.2365758128 -7.0685758128
BXD89 m 33.8616 22.4162397427 78.2722139101 -10.5490139101
BXD90 m 22.3705 25.0621179323 72.0230758128 -27.2820758128
C57BL/6J m 91.508 28.9392410693 148.8418560229 34.1741439771
DBA/2J m 26.5233333333 28.9392410693 83.8571893562 -30.8105226896




  GWAS USING LINEAR MIXED MODELS