Project measure / variable:   Schoonjans1   TCA_plasma_t0_HFD

ID, description, units MPD:112669   TCA_plasma_t0_HFD   plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means273.9   ng/mL
Median of the strain means159.8   ng/mL
SD of the strain means± 245.3
Coefficient of variation (CV)0.8955
Min–max range of strain means50.64   –   985.2   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 8759484.518 250270.9862 1.4255 0.0819
Residuals 121 21243816.5476 175568.7318


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 57.24 18.541   5 8.2916 0.3239 33.986, 77.15 -0.88
BXD100 m 143.4 140.0   9 46.666 0.9766 24.762, 477.9 -0.53
BXD11 m 276.0 125.6   3 72.53 0.4551 192.5, 420.5 0.01
BXD12 m 65.27 37.852   3 21.854 0.5799 31.71, 106.3 -0.85
BXD27 m 366.8 296.6   5 132.6 0.8086 115.5, 845.0 0.38
BXD32 m 87.44 46.905   4 23.452 0.5364 36.258, 139.3 -0.76
BXD34 m 109.4 82.81   4 41.404 0.7569 55.27, 232.6 -0.67
BXD39 m 568.2 705.6   3 407.4 1.2419 158.2, 1383.0 1.2
BXD40 m 118.8 25.541   4 12.77 0.2149 95.99, 151.8 -0.63
BXD43 m 96.05 86.49   5 38.679 0.9004 29.68, 215.0 -0.73
BXD45 m 51.29 13.488   5 6.032 0.263 33.508, 62.7 -0.91
BXD48 m 323.6 219.1   5 97.98 0.6771 79.64, 664.4 0.2
BXD48a m 985.2 1046.0   4 522.8 1.0613 204.6, 2526.0 2.9
BXD49 m 201.1 257.9   5 115.3 1.2822 51.79, 659.6 -0.3
BXD51 m 832.0 332.0   3 191.7 0.399 511.1, 1174.0 2.28
BXD53 m 334.0 184.5   5 82.53 0.5525 119.7, 557.5 0.24
BXD55 m 80.82 25.596   5 11.447 0.3167 48.344, 111.2 -0.79
BXD6 m 962.0 1847.0   5 826.2 1.9205 59.71, 4264.0 2.8
BXD62 m 151.2 50.9   4 25.451 0.3367 109.9, 219.5 -0.5
BXD63 m 536.5 148.6   5 66.45 0.2769 318.0, 685.8 1.07
BXD64 m 215.5 100.7   5 45.042 0.4675 117.0, 352.9 -0.24
BXD66 m 158.7 78.42   3 45.274 0.494 68.4, 209.3 -0.47
BXD67 m 290.1 161.4   5 72.17 0.5563 157.9, 559.7 0.07
BXD69 m 123.2 65.84   4 32.919 0.5346 33.446, 183.6 -0.61
BXD73 m 68.26 29.741   3 17.171 0.4357 42.274, 100.7 -0.84
BXD75 m 464.3 343.0   4 171.5 0.7387 58.94, 751.2 0.78
BXD77 m 161.0 177.7   5 79.49 1.1038 38.746, 471.8 -0.46
BXD79 m 387.2 220.9   5 98.79 0.5705 79.56, 631.4 0.46
BXD8 m 131.5 190.8   3 110.2 1.4506 12.31, 351.6 -0.58
BXD81 m 280.0 266.8   5 119.3 0.9528 54.87, 689.3 0.02
BXD84 m 373.3 288.1   5 128.9 0.7719 107.1, 714.2 0.41
BXD87 m 124.7 103.7   4 51.86 0.8315 26.104, 223.0 -0.61
BXD89 m 50.64 13.248   5 5.9249 0.2616 39.778, 68.23 -0.91
BXD90 m 131.2 41.375   4 20.687 0.3153 94.1, 182.9 -0.58
C57BL/6J m 429.7 327.2   3 188.9 0.7616 200.3, 804.4 0.64
DBA/2J m 125.6 69.3   3 40.013 0.5516 45.806, 170.4 -0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 57.242 187.3866226808 428.2232451617 -313.7392451617
BXD100 m 143.358 139.6697421295 419.8710941864 -133.1550941864
BXD11 m 276.0333333333 241.9150896483 754.9680614222 -202.9013947556
BXD12 m 65.27 241.9150896483 544.2047280889 -413.6647280889
BXD27 m 366.78 187.3866226808 737.7612451617 -4.2012451617
BXD32 m 87.437 209.5046131942 502.2066412796 -327.3326412796
BXD34 m 109.405 209.5046131942 524.1746412796 -305.3646412796
BXD39 m 568.2 241.9150896483 1047.1347280889 89.2652719111
BXD40 m 118.8475 209.5046131942 533.6171412796 -295.9221412796
BXD43 m 96.0548 187.3866226808 467.0360451617 -274.9264451617
BXD45 m 51.2868 187.3866226808 422.2680451617 -319.6944451617
BXD48 m 323.588 187.3866226808 694.5692451617 -47.3932451617
BXD48a m 985.25 209.5046131942 1400.0196412796 570.4803587204
BXD49 m 201.1 187.3866226808 572.0812451617 -169.8812451617
BXD51 m 832.0 241.9150896483 1310.9347280889 353.0652719111
BXD53 m 334.02 187.3866226808 705.0012451617 -36.9612451617
BXD55 m 80.8208 187.3866226808 451.8020451617 -290.1604451617
BXD6 m 962.0 187.3866226808 1332.9812451617 591.0187548383
BXD62 m 151.175 209.5046131942 565.9446412796 -263.5946412796
BXD63 m 536.5 187.3866226808 907.4812451617 165.5187548383
BXD64 m 215.46 187.3866226808 586.4412451617 -155.5212451617
BXD66 m 158.7333333333 241.9150896483 637.6680614222 -320.2013947556
BXD67 m 290.06 187.3866226808 661.0412451617 -80.9212451617
BXD69 m 123.1615 209.5046131942 537.9311412796 -291.6081412796
BXD73 m 68.2646666667 241.9150896483 547.1993947556 -410.6700614222
BXD75 m 464.31 209.5046131942 879.0796412796 49.5403587204
BXD77 m 161.0232 187.3866226808 532.0044451617 -209.9580451617
BXD79 m 387.192 187.3866226808 758.1732451617 16.2107548383
BXD8 m 131.5373333333 241.9150896483 610.4720614222 -347.3973947556
BXD81 m 280.032 187.3866226808 651.0132451617 -90.9492451617
BXD84 m 373.26 187.3866226808 744.2412451617 2.2787548383
BXD87 m 124.736 209.5046131942 539.5056412796 -290.0336412796
BXD89 m 50.6392 187.3866226808 421.6204451617 -320.3420451617
BXD90 m 131.225 209.5046131942 545.9946412796 -283.5446412796
C57BL/6J m 429.6666666667 241.9150896483 908.6013947556 -49.2680614222
DBA/2J m 125.6353333333 241.9150896483 604.5700614222 -353.2993947556




  GWAS USING LINEAR MIXED MODELS