Project measure / variable:   Schoonjans1   TbMCA_plasma_t0_HFD

ID, description, units MPD:112667   TbMCA_plasma_t0_HFD   plasma bile acid tauro-β-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-β-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means214.2   ng/mL
Median of the strain means159.3   ng/mL
SD of the strain means± 144.0
Coefficient of variation (CV)0.6723
Min–max range of strain means40.183   –   554.6   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 2911386.5495 83182.4728 3.1442 < 0.0001
Residuals 121 3201131.0298 26455.6283


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 66.74 31.754   5 14.201 0.4758 29.704, 113.5 -1.02
BXD100 m 113.6 66.61   9 22.203 0.5863 21.394, 255.9 -0.7
BXD11 m 483.9 117.3   3 67.7 0.2423 353.2, 579.9 1.87
BXD12 m 174.2 93.11   3 53.76 0.5346 116.9, 281.6 -0.28
BXD27 m 227.1 161.3   5 72.12 0.7102 92.57, 460.4 0.09
BXD32 m 44.629 21.191   4 10.595 0.4748 17.44, 68.41 -1.18
BXD34 m 158.1 39.374   4 19.687 0.249 114.5, 210.2 -0.39
BXD39 m 252.1 252.8   3 146.0 1.0029 65.22, 539.8 0.26
BXD40 m 239.0 100.5   4 50.23 0.4203 142.5, 379.5 0.17
BXD43 m 196.0 68.53   5 30.647 0.3496 128.4, 294.6 -0.13
BXD45 m 207.1 65.31   5 29.21 0.3153 138.1, 279.9 -0.05
BXD48 m 160.6 105.0   5 46.954 0.6539 50.73, 299.0 -0.37
BXD48a m 401.9 401.3   4 200.7 0.9986 103.8, 993.5 1.3
BXD49 m 444.8 170.3   5 76.16 0.3829 317.9, 729.5 1.6
BXD51 m 456.0 69.5   3 40.128 0.1524 378.8, 513.6 1.68
BXD53 m 202.8 93.98   5 42.031 0.4635 108.6, 338.9 -0.08
BXD55 m 150.1 41.543   5 18.579 0.2768 102.9, 214.0 -0.45
BXD6 m 504.8 485.9   5 217.3 0.9626 148.6, 1356.0 2.02
BXD62 m 290.7 62.13   4 31.067 0.2137 210.0, 359.3 0.53
BXD63 m 205.3 28.232   5 12.626 0.1375 160.1, 236.3 -0.06
BXD64 m 132.7 83.42   5 37.304 0.6285 38.358, 225.2 -0.57
BXD66 m 129.6 31.159   3 17.99 0.2405 94.51, 154.1 -0.59
BXD67 m 126.1 87.71   5 39.223 0.6955 64.81, 270.4 -0.61
BXD69 m 120.8 24.332   4 12.166 0.2015 100.4, 155.6 -0.65
BXD73 m 70.91 30.725   3 17.739 0.4333 51.05, 106.3 -1.0
BXD75 m 332.6 248.3   4 124.1 0.7465 82.65, 647.2 0.82
BXD77 m 84.5 71.42   5 31.939 0.8452 23.724, 197.9 -0.9
BXD79 m 447.8 241.0   5 107.8 0.5382 199.4, 699.0 1.62
BXD8 m 554.6 527.1   3 304.3 0.9504 235.7, 1163.0 2.36
BXD81 m 110.1 124.6   5 55.72 1.1312 11.264, 314.8 -0.72
BXD84 m 121.2 80.66   5 36.072 0.6657 35.73, 221.6 -0.65
BXD87 m 118.1 34.113   4 17.056 0.2889 78.76, 160.8 -0.67
BXD89 m 121.8 20.536   5 9.1839 0.1687 103.0, 153.3 -0.64
BXD90 m 109.2 22.809   4 11.404 0.209 90.77, 140.8 -0.73
C57BL/6J m 112.6 44.222   3 25.532 0.3928 65.67, 153.5 -0.71
DBA/2J m 40.183 31.012   3 17.905 0.7718 16.516, 75.29 -1.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 66.7368 72.7401242029 210.7450619771 -77.2714619771
BXD100 m 113.6071111111 54.2172874699 220.9445321453 6.269690077
BXD11 m 483.9 93.9070965464 669.8138667846 297.9861332154
BXD12 m 174.1666666667 93.9070965464 360.0805334512 -11.7472001179
BXD27 m 227.074 72.7401242029 371.0822619771 83.0657380229
BXD32 m 44.629 81.3259312048 205.6351315512 -116.3771315512
BXD34 m 158.15 81.3259312048 319.1561315512 -2.8561315512
BXD39 m 252.1066666667 93.9070965464 438.0205334512 66.1927998821
BXD40 m 239.0 81.3259312048 400.0061315512 77.9938684488
BXD43 m 196.04 72.7401242029 340.0482619771 52.0317380229
BXD45 m 207.12 72.7401242029 351.1282619771 63.1117380229
BXD48 m 160.562 72.7401242029 304.5702619771 16.5537380229
BXD48a m 401.9 81.3259312048 562.9061315512 240.8938684488
BXD49 m 444.78 72.7401242029 588.7882619771 300.7717380229
BXD51 m 456.0 93.9070965464 641.9138667846 270.0861332154
BXD53 m 202.76 72.7401242029 346.7682619771 58.7517380229
BXD55 m 150.1 72.7401242029 294.1082619771 6.0917380229
BXD6 m 504.84 72.7401242029 648.8482619771 360.8317380229
BXD62 m 290.7 81.3259312048 451.7061315512 129.6938684488
BXD63 m 205.32 72.7401242029 349.3282619771 61.3117380229
BXD64 m 132.7136 72.7401242029 276.7218619771 -11.2946619771
BXD66 m 129.57 93.9070965464 315.4838667846 -56.3438667846
BXD67 m 126.1 72.7401242029 270.1082619771 -17.9082619771
BXD69 m 120.75 81.3259312048 281.7561315512 -40.2561315512
BXD73 m 70.91 93.9070965464 256.8238667846 -115.0038667846
BXD75 m 332.5875 81.3259312048 493.5936315512 171.5813684488
BXD77 m 84.5004 72.7401242029 228.5086619771 -59.5078619771
BXD79 m 447.78 72.7401242029 591.7882619771 303.7717380229
BXD8 m 554.6 93.9070965464 740.5138667846 368.6861332154
BXD81 m 110.1476 72.7401242029 254.1558619771 -33.8606619771
BXD84 m 121.172 72.7401242029 265.1802619771 -22.8362619771
BXD87 m 118.065 81.3259312048 279.0711315512 -42.9411315512
BXD89 m 121.76 72.7401242029 265.7682619771 -22.2482619771
BXD90 m 109.1575 81.3259312048 270.1636315512 -51.8486315512
C57BL/6J m 112.59 93.9070965464 298.5038667846 -73.3238667846
DBA/2J m 40.1833333333 93.9070965464 226.0972001179 -145.7305334512




  GWAS USING LINEAR MIXED MODELS