Project measure / variable:   Schoonjans1   TaMCA_plasma_t0_HFD

ID, description, units MPD:112665   TaMCA_plasma_t0_HFD   plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means72.97   ng/mL
Median of the strain means57.15   ng/mL
SD of the strain means± 59.41
Coefficient of variation (CV)0.8141
Min–max range of strain means11.265   –   272.0   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 542677.4232 15505.0692 1.0288 0.4387
Residuals 121 1823661.7761 15071.5849


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 11.265 4.8121   5 2.1521 0.4272 6.712, 18.507 -1.04
BXD100 m 40.887 52.99   9 17.662 1.2959 5.176, 174.6 -0.54
BXD11 m 81.81 40.006   3 23.097 0.489 58.14, 128.0 0.15
BXD12 m 46.067 35.126   3 20.28 0.7625 20.862, 86.19 -0.45
BXD27 m 126.1 139.4   5 62.35 1.1059 30.318, 354.9 0.89
BXD32 m 16.245 7.1078   4 3.5539 0.4376 7.768, 24.872 -0.95
BXD34 m 34.464 20.378   4 10.189 0.5913 19.184, 64.43 -0.65
BXD39 m 137.5 173.1   3 99.94 1.2591 28.8, 337.1 1.09
BXD40 m 49.018 23.358   4 11.679 0.4765 25.8, 74.76 -0.4
BXD43 m 22.449 18.135   5 8.1101 0.8078 8.396, 49.16 -0.85
BXD45 m 43.93 14.459   5 6.4663 0.3291 30.348, 63.17 -0.49
BXD48 m 119.7 84.65   5 37.855 0.7071 18.604, 223.8 0.79
BXD48a m 269.3 281.1   4 140.6 1.044 57.92, 682.9 3.3
BXD49 m 62.37 56.97   5 25.476 0.9133 33.456, 164.2 -0.18
BXD51 m 132.8 42.374   3 24.465 0.3191 95.96, 179.1 1.01
BXD53 m 101.4 61.24   5 27.386 0.6037 41.085, 170.3 0.48
BXD55 m 33.702 12.399   5 5.545 0.3679 21.366, 52.54 -0.66
BXD6 m 272.0 558.0   5 249.5 2.0513 11.99, 1270.0 3.35
BXD62 m 48.745 19.754   4 9.8771 0.4053 33.412, 77.63 -0.41
BXD63 m 84.72 17.623   5 7.8812 0.208 65.19, 105.1 0.2
BXD64 m 76.01 47.916   5 21.429 0.6304 26.828, 140.1 0.05
BXD66 m 55.88 22.033   3 12.721 0.3943 31.926, 75.28 -0.29
BXD67 m 61.2 40.572   5 18.145 0.663 28.114, 125.8 -0.2
BXD69 m 39.005 21.519   4 10.76 0.5517 11.194, 60.96 -0.57
BXD73 m 25.774 10.088   3 5.8241 0.3914 17.556, 37.032 -0.79
BXD75 m 110.0 67.24   4 33.621 0.6115 22.564, 169.8 0.62
BXD77 m 63.84 68.89   5 30.808 1.079 13.37, 181.4 -0.15
BXD79 m 101.6 60.46   5 27.037 0.5948 26.906, 160.0 0.48
BXD8 m 58.72 75.39   3 43.528 1.284 10.54, 145.6 -0.24
BXD81 m 73.46 72.41   5 32.384 0.9858 9.03, 177.2 0.01
BXD84 m 44.649 29.175   5 13.047 0.6534 17.416, 86.91 -0.48
BXD87 m 17.456 9.3601   4 4.6801 0.5362 6.688, 25.824 -0.93
BXD89 m 34.786 9.8865   5 4.4214 0.2842 22.896, 49.296 -0.64
BXD90 m 51.74 20.84   4 10.42 0.4028 32.28, 75.84 -0.36
C57BL/6J m 58.42 38.99   3 22.511 0.6674 26.558, 101.9 -0.24
DBA/2J m 19.884 15.304   3 8.836 0.7697 7.276, 36.912 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 11.265 54.9027957873 119.9595655598 -97.4295655598
BXD100 m 40.8868888889 40.922127845 121.9030346811 -40.1292569033
BXD11 m 81.81 70.8792045814 222.1340807455 -58.5140807455
BXD12 m 46.0666666667 70.8792045814 186.3907474122 -94.2574140788
BXD27 m 126.0808 54.9027957873 234.7753655598 17.3862344402
BXD32 m 16.2445 61.3831917675 137.7687186883 -105.2797186883
BXD34 m 34.464 61.3831917675 155.9882186883 -87.0602186883
BXD39 m 137.48 70.8792045814 277.8040807455 -2.8440807455
BXD40 m 49.018 61.3831917675 170.5422186883 -72.5062186883
BXD43 m 22.4492 54.9027957873 131.1437655598 -86.2453655598
BXD45 m 43.9304 54.9027957873 152.6249655598 -64.7641655598
BXD48 m 119.7028 54.9027957873 228.3973655598 11.0082344402
BXD48a m 269.28 61.3831917675 390.8042186883 147.7557813117
BXD49 m 62.3724 54.9027957873 171.0669655598 -46.3221655598
BXD51 m 132.7866666667 70.8792045814 273.1107474122 -7.5374140788
BXD53 m 101.4334 54.9027957873 210.1279655598 -7.2611655598
BXD55 m 33.702 54.9027957873 142.3965655598 -74.9925655598
BXD6 m 272.019 54.9027957873 380.7135655598 163.3244344402
BXD62 m 48.745 61.3831917675 170.2692186883 -72.7792186883
BXD63 m 84.716 54.9027957873 193.4105655598 -23.9785655598
BXD64 m 76.0144 54.9027957873 184.7089655598 -32.6801655598
BXD66 m 55.882 70.8792045814 196.2060807455 -84.4420807455
BXD67 m 61.1952 54.9027957873 169.8897655598 -47.4993655598
BXD69 m 39.0055 61.3831917675 160.5297186883 -82.5187186883
BXD73 m 25.774 70.8792045814 166.0980807455 -114.5500807455
BXD75 m 109.9685 61.3831917675 231.4927186883 -11.5557186883
BXD77 m 63.8424 54.9027957873 172.5369655598 -44.8521655598
BXD79 m 101.6396 54.9027957873 210.3341655598 -7.0549655598
BXD8 m 58.716 70.8792045814 199.0400807455 -81.6080807455
BXD81 m 73.456 54.9027957873 182.1505655598 -35.2385655598
BXD84 m 44.6488 54.9027957873 153.3433655598 -64.0457655598
BXD87 m 17.456 61.3831917675 138.9802186883 -104.0682186883
BXD89 m 34.7856 54.9027957873 143.4801655598 -73.9089655598
BXD90 m 51.737 61.3831917675 173.2612186883 -69.7872186883
C57BL/6J m 58.4233333333 70.8792045814 198.7474140788 -81.9007474122
DBA/2J m 19.884 70.8792045814 160.2080807455 -120.4400807455




  GWAS USING LINEAR MIXED MODELS