Project measure / variable:   Schoonjans1   TaMCA_plasma_t0_CD

ID, description, units MPD:112664   TaMCA_plasma_t0_CD   plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means31.413   ng/mL
Median of the strain means28.368   ng/mL
SD of the strain means± 21.693
Coefficient of variation (CV)0.6906
Min–max range of strain means8.0098   –   129.8   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 81147.2871 2318.4939 1.6687 0.0209
Residuals 130 180618.3451 1389.3719


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 8.0098 3.7209   5 1.664 0.4645 3.976, 14.115 -1.08
BXD100 m 31.645 10.004   5 4.4741 0.3161 19.714, 46.308 0.01
BXD11 m 30.938 25.463   4 12.732 0.823 5.084, 55.46 -0.02
BXD12 m 25.954 12.338   3 7.1232 0.4754 17.608, 40.126 -0.25
BXD27 m 29.35 19.868   4 9.9338 0.6769 14.888, 58.69 -0.1
BXD32 m 34.984 23.161   5 10.358 0.6621 10.84, 67.23 0.16
BXD34 m 27.468 15.264   5 6.8262 0.5557 6.212, 43.258 -0.18
BXD39 m 38.045 27.52   3 15.889 0.7234 20.942, 69.79 0.31
BXD40 m 24.554 10.309   4 5.1544 0.4198 10.156, 34.596 -0.32
BXD43 m 13.427 8.6332   7 3.263 0.643 4.384, 26.324 -0.83
BXD45 m 47.401 34.044   4 17.022 0.7182 17.226, 83.42 0.74
BXD48 m 17.664 15.17   5 6.7844 0.8588 6.236, 43.656 -0.63
BXD48a m 26.671 17.587   4 8.7933 0.6594 7.118, 49.762 -0.22
BXD49 m 20.71 4.2365   5 1.8946 0.2046 14.982, 25.144 -0.49
BXD51 m 28.3 11.555   5 5.1675 0.4083 9.326, 38.77 -0.14
BXD53 m 39.045 24.785   4 12.393 0.6348 13.722, 72.11 0.35
BXD55 m 9.326 1.1819   5 0.52854 0.1267 7.7, 10.594 -1.02
BXD6 m 65.66 42.736   5 19.112 0.6509 13.05, 114.3 1.58
BXD62 m 28.436 25.145   5 11.245 0.8842 11.12, 70.59 -0.14
BXD63 m 11.988 1.995   4 0.99749 0.1664 10.212, 14.264 -0.9
BXD64 m 68.19 28.737   5 12.851 0.4214 31.902, 108.6 1.7
BXD66 m 22.031 13.57   5 6.0688 0.616 11.09, 43.89 -0.43
BXD67 m 16.303 10.268   4 5.1341 0.6298 5.17, 29.806 -0.7
BXD69 m 49.262 29.944   5 13.391 0.6079 16.61, 79.1 0.82
BXD73 m 29.58 24.192   4 12.096 0.8179 7.208, 63.49 -0.08
BXD75 m 129.8 182.2   5 81.48 1.4037 15.388, 451.5 4.54
BXD77 m 33.378 16.546   5 7.3997 0.4957 18.836, 60.11 0.09
BXD79 m 32.551 13.685   5 6.12 0.4204 17.77, 51.39 0.05
BXD8 m 29.196 27.765   5 12.417 0.951 3.37, 72.91 -0.1
BXD81 m 13.292 12.062   3 6.9643 0.9075 4.375, 27.017 -0.84
BXD84 m 23.74 9.4115   5 4.209 0.3964 7.294, 30.693 -0.35
BXD87 m 14.126 4.5981   5 2.0563 0.3255 9.138, 21.528 -0.8
BXD89 m 26.137 23.154   6 9.4527 0.8859 6.986, 67.87 -0.24
BXD90 m 39.989 21.567   4 10.784 0.5393 8.78, 58.38 0.4
C57BL/6J m 14.86 5.177   5 2.3152 0.3484 9.924, 22.296 -0.76
DBA/2J m 28.863 21.702   4 10.851 0.7519 8.65, 57.52 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 8.0098 16.6695643916 40.9885395597 -24.9689395597
BXD100 m 31.6452 16.6695643916 64.6239395597 -1.3335395597
BXD11 m 30.938 18.6371395675 67.8093517339 -5.9333517339
BXD12 m 25.954 21.5203150924 68.5293696979 -16.6213696979
BXD27 m 29.3505 18.6371395675 66.2218517339 -7.5208517339
BXD32 m 34.984 16.6695643916 67.9627395597 2.0052604403
BXD34 m 27.4684 16.6695643916 60.4471395597 -5.5103395597
BXD39 m 38.0446666667 21.5203150924 80.6200363646 -4.5307030312
BXD40 m 24.554 18.6371395675 61.4253517339 -12.3173517339
BXD43 m 13.4271428571 14.08835327 41.2992649116 -14.4449791973
BXD45 m 47.401 18.6371395675 84.2723517339 10.5296482661
BXD48 m 17.664 16.6695643916 50.6427395597 -15.3147395597
BXD48a m 26.6705 18.6371395675 63.5418517339 -10.2008517339
BXD49 m 20.7104 16.6695643916 53.6891395597 -12.2683395597
BXD51 m 28.3004 16.6695643916 61.2791395597 -4.6783395597
BXD53 m 39.045 18.6371395675 75.9163517339 2.1736482661
BXD55 m 9.326 16.6695643916 42.3047395597 -23.6527395597
BXD6 m 65.6584 16.6695643916 98.6371395597 32.6796604403
BXD62 m 28.4364 16.6695643916 61.4151395597 -4.5423395597
BXD63 m 11.9875 18.6371395675 48.8588517339 -24.8838517339
BXD64 m 68.1904 16.6695643916 101.1691395597 35.2116604403
BXD66 m 22.0312 16.6695643916 55.0099395597 -10.9475395597
BXD67 m 16.303 18.6371395675 53.1743517339 -20.5683517339
BXD69 m 49.2616 16.6695643916 82.2403395597 16.2828604403
BXD73 m 29.5795 18.6371395675 66.4508517339 -7.2918517339
BXD75 m 129.804 16.6695643916 162.7827395597 96.8252604403
BXD77 m 33.3784 16.6695643916 66.3571395597 0.3996604403
BXD79 m 32.5508 16.6695643916 65.5295395597 -0.4279395597
BXD8 m 29.1964 16.6695643916 62.1751395597 -3.7823395597
BXD81 m 13.292 21.5203150924 55.8673696979 -29.2833696979
BXD84 m 23.7402 16.6695643916 56.7189395597 -9.2385395597
BXD87 m 14.1256 16.6695643916 47.1043395597 -18.8531395597
BXD89 m 26.1373333333 15.2171607351 56.2426659582 -3.9679992916
BXD90 m 39.9895 18.6371395675 76.8608517339 3.1181482661
C57BL/6J m 14.8604 16.6695643916 47.8391395597 -18.1183395597
DBA/2J m 28.8625 18.6371395675 65.7338517339 -8.0088517339




  GWAS USING LINEAR MIXED MODELS