Project measure / variable:   Schoonjans1   GCA_plasma_t0_HFD

ID, description, units MPD:112661   GCA_plasma_t0_HFD   plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   32 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested32 strains
Mean of the strain means1.5081   ng/mL
Median of the strain means0.75475   ng/mL
SD of the strain means± 2.136
Coefficient of variation (CV)1.4163
Min–max range of strain means0.036   –   11.306   ng/mL
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 28 540.841 19.3158 1.012 0.4641
Residuals 84 1603.2773 19.0866


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.27 0.16302   5 0.07291 0.6038 0.016, 0.404 -0.58
BXD100 m 0.097 0.01838   2   0.013 0.1895 0.084, 0.11 -0.66
BXD11 m 0.41733 0.43501   3 0.25115 1.0424 0.104, 0.914 -0.51
BXD12 m 0.394 0.0   1   0.0 0.0 0.394, 0.394 -0.52
BXD27 m 2.643 3.5652   2   2.521 1.3489 0.122, 5.164 0.53
BXD32 m 0.579 0.36716   4 0.18358 0.6341 0.104, 0.892 -0.43
BXD34 m 1.0925 1.6667   4 0.83336 1.5256 0.046, 3.58 -0.19
BXD39 m 1.948 2.946   3 1.7009 1.5123 0.008, 5.338 0.21
BXD40 m 0.2565 0.1682   4 0.0841 0.6558 0.018, 0.4 -0.59
BXD43 m 0.052 0.0   1   0.0 0.0 0.052, 0.052 -0.68
BXD45 m 0.0808 0.03596   5 0.01608 0.4451 0.022, 0.112 -0.67
BXD48 m 0.7185 0.74131   4 0.37066 1.0317 0.106, 1.66 -0.37
BXD48a m 4.2295 7.2544   4 3.6272 1.7152 0.336, 15.104 1.27
BXD49 m 1.8936 2.7355   5 1.2234 1.4446 0.368, 6.77 0.18
BXD51 m 0.28267 0.34416   3 0.1987 1.2176 0.012, 0.67 -0.57
BXD53 m 1.8157 1.2708   4 0.63539 0.6999 0.54, 3.438 0.14
BXD55 m 0.8808 0.42441   5 0.1898 0.4818 0.406, 1.514 -0.29
BXD6 m 11.306 20.343   4 10.171 1.7994 0.376, 41.794 4.59
BXD63 m 2.9596 2.5926   5 1.1595 0.876 0.49, 5.764 0.68
BXD64 m 3.8624 3.2502   5 1.4535 0.8415 1.74, 9.52 1.1
BXD67 m 1.364 0.72381   5 0.3237 0.5307 0.512, 2.128 -0.07
BXD69 m 0.445 0.43088   4 0.21544 0.9683 0.034, 1.05 -0.5
BXD73 m 2.1153 0.21885   3 0.12636 0.1035 1.952, 2.364 0.28
BXD75 m 1.624 1.4035   4 0.70176 0.8642 0.4, 3.638 0.05
BXD77 m 0.791 1.0089   4 0.50444 1.2755 0.01, 2.214 -0.34
BXD79 m 0.2025 0.14216   4 0.07108 0.702 0.01, 0.33 -0.61
BXD8 m 0.39733 0.59993   3 0.34637 1.5099 0.042, 1.09 -0.52
BXD81 m 3.1552 3.0648   5 1.3706 0.9713 0.75, 7.064 0.77
BXD84 m 0.24533 0.22041   3 0.12725 0.8984 0.004, 0.436 -0.59
BXD89 m 0.174 0.08646   4 0.04323 0.4969 0.106, 0.296 -0.62
BXD90 m 0.036 0.0   1   0.0 0.0 0.036, 0.036 -0.69
C57BL/6J m 1.9313 1.9764   3 1.1411 1.0233 0.598, 4.202 0.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.27 1.9537980531 4.1553416957 -3.6153416957
BXD100 m 0.097 3.0892259679 6.2402646232 -6.0462646232
BXD11 m 0.4173333333 2.5223424405 5.4332878939 -4.5986212273
BXD27 m 2.643 3.0892259679 8.7862646232 -3.5002646232
BXD32 m 0.579 2.1844126305 4.9229440737 -3.7649440737
BXD34 m 1.0925 2.1844126305 5.4364440737 -3.2514440737
BXD39 m 1.948 2.5223424405 6.9639545606 -3.0679545606
BXD40 m 0.2565 2.1844126305 4.6004440737 -4.0874440737
BXD45 m 0.0808 1.9537980531 3.9661416957 -3.8045416957
BXD48 m 0.7185 2.1844126305 5.0624440737 -3.6254440737
BXD48a m 4.2295 2.1844126305 8.5734440737 -0.1144440737
BXD49 m 1.8936 1.9537980531 5.7789416957 -1.9917416957
BXD51 m 0.2826666667 2.5223424405 5.2986212273 -4.7332878939
BXD53 m 1.81575 2.1844126305 6.1596940737 -2.5281940737
BXD55 m 0.8808 1.9537980531 4.7661416957 -3.0045416957
BXD6 m 11.305605 2.1844126305 15.6495490737 6.9616609263
BXD63 m 2.9596 1.9537980531 6.8449416957 -0.9257416957
BXD64 m 3.8624 1.9537980531 7.7477416957 -0.0229416957
BXD67 m 1.364 1.9537980531 5.2493416957 -2.5213416957
BXD69 m 0.445 2.1844126305 4.7889440737 -3.8989440737
BXD73 m 2.1153333333 2.5223424405 7.1312878939 -2.9006212273
BXD75 m 1.624 2.1844126305 5.9679440737 -2.7199440737
BXD77 m 0.791 2.1844126305 5.1349440737 -3.5529440737
BXD79 m 0.2025 2.1844126305 4.5464440737 -4.1414440737
BXD8 m 0.3973333333 2.5223424405 5.4132878939 -4.6186212273
BXD81 m 3.1552 1.9537980531 7.0405416957 -0.7301416957
BXD84 m 0.2453333333 2.5223424405 5.2612878939 -4.7706212273
BXD89 m 0.174 2.1844126305 4.5179440737 -4.1699440737
C57BL/6J m 1.9313333333 2.5223424405 6.9472878939 -3.0846212273




  GWAS USING LINEAR MIXED MODELS