Project measure / variable:   Schoonjans1   GCA_plasma_t0_CD

ID, description, units MPD:112660   GCA_plasma_t0_CD   plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.98183   ng/mL
Median of the strain means0.51133   ng/mL
SD of the strain means± 1.1905
Coefficient of variation (CV)1.2125
Min–max range of strain means0.094   –   6.367   ng/mL
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 223.0211 6.5594 2.1465 0.0016
Residuals 107 326.9816 3.0559


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.59658 0.52055   5 0.2328 0.8726 0.104, 1.3029 -0.32
BXD100 m 0.3135 0.16394   4 0.08197 0.5229 0.11, 0.486 -0.56
BXD11 m 0.364 0.09007   3 0.052 0.2474 0.26, 0.416 -0.52
BXD12 m 0.54 0.15839   2   0.112 0.2933 0.428, 0.652 -0.37
BXD27 m 0.68667 0.98321   3 0.56766 1.4319 0.062, 1.82 -0.25
BXD32 m 2.0456 1.4141   5 0.63242 0.6913 0.332, 3.754 0.89
BXD34 m 1.5716 0.87062   5 0.38936 0.554 0.304, 2.474 0.5
BXD39 m 0.45 0.36204   2   0.256 0.8045 0.194, 0.706 -0.45
BXD40 m 1.2805 0.81251   4 0.40626 0.6345 0.31, 2.268 0.25
BXD43 m 0.14333 0.12266   3 0.07082 0.8558 0.014, 0.258 -0.7
BXD45 m 0.4015 0.43324   4 0.21662 1.0791 0.016, 0.964 -0.49
BXD48 m 0.538 0.57202   5 0.25581 1.0632 0.088, 1.304 -0.37
BXD48a m 0.4195 0.34807   4 0.17403 0.8297 0.05, 0.858 -0.47
BXD49 m 1.0268 0.19742   5 0.08829 0.1923 0.866, 1.276 0.04
BXD51 m 0.094 0.03394   2   0.024 0.3611 0.07, 0.118 -0.75
BXD53 m 0.771 0.75326   4 0.37663 0.977 0.198, 1.88 -0.18
BXD55 m 0.232 0.16187   5 0.07239 0.6977 0.068, 0.416 -0.63
BXD6 m 0.594 0.5423   5 0.24252 0.913 0.056, 1.29 -0.33
BXD62 m 0.32933 0.2829   3 0.16333 0.859 0.026, 0.586 -0.55
BXD63 m 0.48467 0.08663   3 0.05002 0.1787 0.416, 0.582 -0.42
BXD64 m 1.8692 0.30308   5 0.13554 0.1621 1.57, 2.31 0.75
BXD66 m 0.152 0.0   1   0.0 0.0 0.152, 0.152 -0.7
BXD67 m 1.7835 0.24713   4 0.12357 0.1386 1.55, 2.1 0.67
BXD69 m 1.68 1.3104   5 0.58603 0.78 0.284, 3.21 0.59
BXD73 m 3.734 2.4649   4 1.2325 0.6601 2.112, 7.37 2.31
BXD75 m 6.367 8.2611   5 3.6945 1.2975 0.614, 20.754 4.52
BXD77 m 1.5216 0.89808   5 0.40163 0.5902 0.532, 2.56 0.45
BXD79 m 0.382 0.12044   4 0.06022 0.3153 0.238, 0.526 -0.5
BXD8 m 0.365 0.26616   4 0.13308 0.7292 0.056, 0.598 -0.52
BXD81 m 0.45277 0.55783   2   0.39444 1.232 0.05833, 0.84722 -0.44
BXD84 m 0.3852 0.09039   5 0.04043 0.2347 0.236, 0.464 -0.5
BXD87 m 1.708 0.66994   5 0.2996 0.3922 0.746, 2.508 0.61
BXD89 m 0.29433 0.27222   6 0.11113 0.9249 0.1, 0.832 -0.58
BXD90 m 0.3265 0.26969   4 0.13484 0.826 0.068, 0.646 -0.55
C57BL/6J m 1.1116 0.1697   5 0.07589 0.1527 0.868, 1.28 0.11
DBA/2J m 0.33067 0.28399   3 0.16396 0.8588 0.034, 0.6 -0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.59658 0.7817803673 2.1463683993 -0.9532083993
BXD100 m 0.3135 0.8740570224 2.0462161058 -1.4192161058
BXD11 m 0.364 1.0092741143 2.3647682202 -1.6367682202
BXD12 m 0.54 1.2361032953 2.9904306165 -1.9104306165
BXD27 m 0.6866666667 1.0092741143 2.6874348868 -1.3141015535
BXD32 m 2.0456 0.7817803673 3.5953883993 0.4958116007
BXD34 m 1.5716 0.7817803673 3.1213883993 0.0218116007
BXD39 m 0.45 1.2361032953 2.9004306165 -2.0004306165
BXD40 m 1.2805 0.8740570224 3.0132161058 -0.4522161058
BXD43 m 0.1433333333 1.0092741143 2.1441015535 -1.8574348868
BXD45 m 0.4015 0.8740570224 2.1342161058 -1.3312161058
BXD48 m 0.538 0.7817803673 2.0877883993 -1.0117883993
BXD48a m 0.4195 0.8740570224 2.1522161058 -1.3132161058
BXD49 m 1.0268 0.7817803673 2.5765883993 -0.5229883993
BXD51 m 0.094 1.2361032953 2.5444306165 -2.3564306165
BXD53 m 0.771 0.8740570224 2.5037161058 -0.9617161058
BXD55 m 0.232 0.7817803673 1.7817883993 -1.3177883993
BXD6 m 0.594 0.7817803673 2.1437883993 -0.9557883993
BXD62 m 0.3293333333 1.0092741143 2.3301015535 -1.6714348868
BXD63 m 0.4846666667 1.0092741143 2.4854348868 -1.5161015535
BXD64 m 1.8692 0.7817803673 3.4189883993 0.3194116007
BXD67 m 1.7835 0.8740570224 3.5162161058 0.0507838942
BXD69 m 1.68 0.7817803673 3.2297883993 0.1302116007
BXD73 m 3.734 0.8740570224 5.4667161058 2.0012838942
BXD75 m 6.36704 0.7817803673 7.9168283993 4.8172516007
BXD77 m 1.5216 0.7817803673 3.0713883993 -0.0281883993
BXD79 m 0.382 0.8740570224 2.1147161058 -1.3507161058
BXD8 m 0.365 0.8740570224 2.0977161058 -1.3677161058
BXD81 m 0.452775 1.2361032953 2.9032056165 -1.9976556165
BXD84 m 0.3852 0.7817803673 1.9349883993 -1.1645883993
BXD87 m 1.708 0.7817803673 3.2577883993 0.1582116007
BXD89 m 0.2943333333 0.7136645703 1.7090901094 -1.1204234427
BXD90 m 0.3265 0.8740570224 2.0592161058 -1.4062161058
C57BL/6J m 1.1116 0.7817803673 2.6613883993 -0.4381883993
DBA/2J m 0.3306666667 1.0092741143 2.3314348868 -1.6701015535




  GWAS USING LINEAR MIXED MODELS