Project measure / variable:   Schoonjans1   DCA_plasma_t0_CD

ID, description, units MPD:112658   DCA_plasma_t0_CD   plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means47.37   ng/mL
Median of the strain means32.547   ng/mL
SD of the strain means± 45.636
Coefficient of variation (CV)0.9634
Min–max range of strain means0.3105   –   234.8   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 352421.6371 10069.1896 9.8572 < 0.0001
Residuals 130 132795.5155 1021.504


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 75.97 51.05   5 22.832 0.672 33.116, 164.6 0.63
BXD100 m 7.0348 1.345   5 0.60151 0.1912 5.158, 8.93 -0.88
BXD11 m 31.945 14.612   4 7.3058 0.4574 10.968, 44.316 -0.34
BXD12 m 6.216 3.6589   3 2.1124 0.5886 3.93, 10.436 -0.9
BXD27 m 25.478 10.101   4 5.0503 0.3964 14.96, 38.904 -0.48
BXD32 m 75.84 54.01   5 24.154 0.7122 22.426, 156.2 0.62
BXD34 m 19.513 3.9043   5 1.746 0.2001 15.3, 24.716 -0.61
BXD39 m 20.938 3.0421   3 1.7563 0.1453 17.696, 23.73 -0.58
BXD40 m 26.023 5.2411   4 2.6205 0.2014 19.89, 31.78 -0.47
BXD43 m 12.168 7.3102   7 2.763 0.6008 4.022, 24.294 -0.77
BXD45 m 61.68 47.939   4 23.97 0.7772 34.744, 133.5 0.31
BXD48 m 98.28 21.923   5 9.8044 0.2231 69.73, 128.9 1.12
BXD48a m 24.716 6.9057   4 3.4528 0.2794 17.562, 33.186 -0.5
BXD49 m 79.19 23.09   5 10.326 0.2916 52.29, 102.7 0.7
BXD51 m 16.131 11.607   5 5.1906 0.7195 5.632, 32.906 -0.68
BXD53 m 45.831 17.992   4 8.9959 0.3926 28.836, 69.66 -0.03
BXD55 m 52.98 19.647   5 8.7863 0.3708 29.992, 77.86 0.12
BXD6 m 0.3105 0.28321   4 0.14161 0.9121 0.078, 0.718 -1.03
BXD62 m 39.575 27.148   5 12.141 0.686 16.678, 80.27 -0.17
BXD63 m 56.42 7.0176   4 3.5088 0.1244 48.86, 65.69 0.2
BXD64 m 19.218 5.5285   5 2.4724 0.2877 11.816, 24.896 -0.62
BXD66 m 13.757 6.5535   5 2.9308 0.4764 7.49, 22.77 -0.74
BXD67 m 11.005 4.8664   4 2.4332 0.4422 4.338, 15.326 -0.8
BXD69 m 43.362 3.0384   5 1.3588 0.0701 39.11, 47.578 -0.09
BXD73 m 111.7 58.57   4 29.286 0.5245 56.69, 194.4 1.41
BXD75 m 125.7 16.8   5 7.5134 0.1336 105.3, 144.2 1.72
BXD77 m 33.361 15.649   5 6.9984 0.4691 11.088, 52.61 -0.31
BXD79 m 50.05 27.473   5 12.286 0.5489 8.776, 73.19 0.06
BXD8 m 24.173 12.301   5 5.5011 0.5089 10.59, 41.402 -0.51
BXD81 m 63.53 68.71   3 39.668 1.0815 14.164, 142.0 0.35
BXD84 m 33.148 10.331   5 4.62 0.3116 19.556, 47.834 -0.31
BXD87 m 234.8 107.5   5 48.093 0.458 123.7, 392.1 4.11
BXD89 m 17.939 10.542   6 4.3036 0.5876 6.476, 31.518 -0.64
BXD90 m 8.5476 4.2809   5 1.9145 0.5008 3.578, 15.316 -0.85
C57BL/6J m 109.1 68.12   5 30.466 0.6247 44.598, 223.1 1.35
DBA/2J m 29.698 9.1015   4 4.5507 0.3065 17.236, 38.718 -0.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 75.9732 14.293382841 104.2509485403 47.6954514597
BXD100 m 7.0348 14.293382841 35.3125485403 -21.2429485403
BXD11 m 31.9445 15.9804878305 63.5599839934 0.3290160066
BXD12 m 6.216 18.4526779014 42.7224163883 -30.2904163883
BXD27 m 25.478 15.9804878305 57.0934839934 -6.1374839934
BXD32 m 75.84 14.293382841 104.1177485403 47.5622514597
BXD34 m 19.5132 14.293382841 47.7909485403 -8.7645485403
BXD39 m 20.938 18.4526779014 57.4444163883 -15.5684163883
BXD40 m 26.0235 15.9804878305 57.6389839934 -5.5919839934
BXD43 m 12.1682857143 12.0801133226 36.0673452072 -11.7307737787
BXD45 m 61.6785 15.9804878305 93.2939839934 30.0630160066
BXD48 m 98.278 14.293382841 126.5557485403 70.0002514597
BXD48a m 24.7165 15.9804878305 56.3319839934 -6.8989839934
BXD49 m 79.186 14.293382841 107.4637485403 50.9082514597
BXD51 m 16.1312 14.293382841 44.4089485403 -12.1465485403
BXD53 m 45.8305 15.9804878305 77.4459839934 14.2150160066
BXD55 m 52.9796 14.293382841 81.2573485403 24.7018514597
BXD6 m 0.3105 15.9804878305 31.9259839934 -31.3049839934
BXD62 m 39.5752 14.293382841 67.8529485403 11.2974514597
BXD63 m 56.4175 15.9804878305 88.0329839934 24.8020160066
BXD64 m 19.218 14.293382841 47.4957485403 -9.0597485403
BXD66 m 13.7572 14.293382841 42.0349485403 -14.5205485403
BXD67 m 11.0045 15.9804878305 42.6199839934 -20.6109839934
BXD69 m 43.362 14.293382841 71.6397485403 15.0842514597
BXD73 m 111.675 15.9804878305 143.2904839934 80.0595160066
BXD75 m 125.74 14.293382841 154.0177485403 97.4622514597
BXD77 m 33.3612 14.293382841 61.6389485403 5.0834514597
BXD79 m 50.0496 14.293382841 78.3273485403 21.7718514597
BXD8 m 24.1728 14.293382841 52.4505485403 -4.1049485403
BXD81 m 63.5316666667 18.4526779014 100.0380830549 27.0252502784
BXD84 m 33.1484 14.293382841 61.4261485403 4.8706514597
BXD87 m 234.78 14.293382841 263.0577485403 206.5022514597
BXD89 m 17.939 13.0480136752 43.752934585 -7.874934585
BXD90 m 8.5476 14.293382841 36.8253485403 -19.7301485403
C57BL/6J m 109.0536 14.293382841 137.3313485403 80.7758514597
DBA/2J m 29.698 15.9804878305 61.3134839934 -1.9174839934




  GWAS USING LINEAR MIXED MODELS