Project measure / variable:   Schoonjans1   CDCA_plasma_t0_HFD

ID, description, units MPD:112657   CDCA_plasma_t0_HFD   plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means2.3797   ng/mL
Median of the strain means1.7092   ng/mL
SD of the strain means± 2.2641
Coefficient of variation (CV)0.9514
Min–max range of strain means0.23067   –   9.4944   ng/mL
Mean sample size per strain4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 824.4728 23.5564 1.0605 0.3963
Residuals 112 2487.6843 22.2115


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.2724 0.38628   5 0.17275 1.4181 0.056, 0.95 -0.93
BXD100 m 0.23067 0.2224   6 0.09079 0.9642 0.008, 0.546 -0.95
BXD11 m 1.6853 1.0531   3 0.60801 0.6249 0.682, 2.782 -0.31
BXD12 m 1.1853 0.8586   3 0.49571 0.7244 0.272, 1.976 -0.53
BXD27 m 9.4944 18.736   5 8.3788 1.9733 0.404, 42.982 3.14
BXD32 m 2.52 2.0858   4 1.0429 0.8277 0.458, 4.898 0.06
BXD34 m 2.0075 2.7316   4 1.3658 1.3607 0.204, 6.066 -0.16
BXD39 m 5.273 4.8578   2   3.435 0.9213 1.838, 8.708 1.28
BXD40 m 2.7465 2.9008   4 1.4504 1.0562 0.68, 6.864 0.16
BXD43 m 0.68733 0.29604   3 0.17092 0.4307 0.378, 0.968 -0.75
BXD45 m 2.3916 1.1757   5 0.52579 0.4916 0.946, 4.176 0.01
BXD48 m 1.192 1.7037   5 0.76192 1.4293 0.11, 4.196 -0.52
BXD48a m 1.4215 0.89058   4 0.44529 0.6265 0.708, 2.72 -0.42
BXD49 m 8.826 10.418   5 4.659 1.1803 0.694, 24.402 2.85
BXD51 m 0.29 0.20501   3 0.11836 0.7069 0.086, 0.496 -0.92
BXD53 m 3.189 1.7069   5 0.76335 0.5352 1.716, 5.2 0.36
BXD55 m 6.8084 8.1603   5 3.6494 1.1986 0.806, 20.568 1.96
BXD6 m 2.7713 2.4999   5 1.118 0.9021 0.75882, 6.3778 0.17
BXD62 m 0.732 0.5987   4 0.29935 0.8179 0.186, 1.528 -0.73
BXD63 m 0.8948 0.73109   5 0.32695 0.817 0.232, 2.13 -0.66
BXD64 m 1.5376 1.9369   5 0.86619 1.2597 0.116, 4.902 -0.37
BXD66 m 0.67408 0.16643   3 0.09609 0.2469 0.53, 0.85625 -0.75
BXD67 m 1.9135 0.72857   4 0.36428 0.3808 0.958, 2.732 -0.21
BXD69 m 4.795 5.202   4 2.601 1.0849 2.164, 12.598 1.07
BXD73 m 2.772 2.1421   3 1.2367 0.7728 1.304, 5.23 0.17
BXD75 m 2.6215 1.7584   4 0.87918 0.6707 1.404, 5.172 0.11
BXD77 m 2.7412 1.9449   5 0.8698 0.7095 1.17, 5.662 0.16
BXD79 m 0.504 0.26412   5 0.11812 0.524 0.246, 0.948 -0.83
BXD8 m 2.9393 3.7169   3 2.1459 1.2645 0.336, 7.196 0.25
BXD81 m 1.2396 0.45985   5 0.20565 0.371 0.52, 1.766 -0.5
BXD84 m 0.274 0.0897   4 0.04485 0.3274 0.17, 0.372 -0.93
BXD87 m 0.801 0.97035   4 0.48518 1.2114 0.192, 2.25 -0.7
BXD89 m 4.7424 4.0445   5 1.8088 0.8528 1.028, 10.614 1.04
BXD90 m 1.1505 1.024   4 0.512 0.89 0.254, 2.452 -0.54
C57BL/6J m 1.733 1.6617   2   1.175 0.9589 0.558, 2.908 -0.29
DBA/2J m 0.612 0.37323   3 0.21548 0.6099 0.372, 1.042 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.2724 2.1076748623 4.4484875671 -3.9036875671
BXD100 m 0.2306666667 1.92403511 4.0428956044 -3.581562271
BXD11 m 1.6853333333 2.720996547 7.0766391999 -3.7059725332
BXD12 m 1.1853333333 2.720996547 6.5766391999 -4.2059725332
BXD27 m 9.4944 2.1076748623 13.6704875671 5.3183124329
BXD32 m 2.52 2.3564521333 7.18900784 -2.14900784
BXD34 m 2.0075 2.3564521333 6.67650784 -2.66150784
BXD39 m 5.273 3.332526566 11.8759742102 -1.3299742102
BXD40 m 2.7465 2.3564521333 7.41550784 -1.92250784
BXD43 m 0.6873333333 2.720996547 6.0786391999 -4.7039725332
BXD45 m 2.3916 2.1076748623 6.5676875671 -1.7844875671
BXD48 m 1.192 2.1076748623 5.3680875671 -2.9840875671
BXD48a m 1.4215 2.3564521333 6.09050784 -3.24750784
BXD49 m 8.826 2.1076748623 13.0020875671 4.6499124329
BXD51 m 0.29 2.720996547 5.6813058666 -5.1013058666
BXD53 m 3.189 2.1076748623 7.3650875671 -0.9870875671
BXD55 m 6.8084 2.1076748623 10.9844875671 2.6323124329
BXD6 m 2.771324 2.1076748623 6.9474115671 -1.4047635671
BXD62 m 0.732 2.3564521333 5.40100784 -3.93700784
BXD63 m 0.8948 2.1076748623 5.0708875671 -3.2812875671
BXD64 m 1.5376 2.1076748623 5.7136875671 -2.6384875671
BXD66 m 0.6740833333 2.720996547 6.0653891999 -4.7172225332
BXD67 m 1.9135 2.3564521333 6.58250784 -2.75550784
BXD69 m 4.795 2.3564521333 9.46400784 0.12599216
BXD73 m 2.772 2.720996547 8.1633058666 -2.6193058666
BXD75 m 2.6215 2.3564521333 7.29050784 -2.04750784
BXD77 m 2.7412 2.1076748623 6.9172875671 -1.4348875671
BXD79 m 0.504 2.1076748623 4.6800875671 -3.6720875671
BXD8 m 2.9393333333 2.720996547 8.3306391999 -2.4519725332
BXD81 m 1.2396 2.1076748623 5.4156875671 -2.9364875671
BXD84 m 0.274 2.3564521333 4.94300784 -4.39500784
BXD87 m 0.801 2.3564521333 5.47000784 -3.86800784
BXD89 m 4.7424 2.1076748623 8.9184875671 0.5663124329
BXD90 m 1.1505 2.3564521333 5.81950784 -3.51850784
C57BL/6J m 1.733 3.332526566 8.3359742102 -4.8699742102
DBA/2J m 0.612 2.720996547 6.0033058666 -4.7793058666




  GWAS USING LINEAR MIXED MODELS