Project measure / variable:   Schoonjans1   CA_plasma_t0_CD

ID, description, units MPD:112654   CA_plasma_t0_CD   plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means52.71   ng/mL
Median of the strain means19.402   ng/mL
SD of the strain means± 70.0
Coefficient of variation (CV)1.328
Min–max range of strain means1.853   –   272.7   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 839762.9359 23993.2267 4.5157 < 0.0001
Residuals 131 696038.5936 5313.2717


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 23.007 48.855   5 21.849 2.1235 0.768, 110.4 -0.42
BXD100 m 6.092 4.1862   5 1.8721 0.6872 3.17, 13.384 -0.67
BXD11 m 10.891 8.4617   4 4.2309 0.7769 3.084, 20.646 -0.6
BXD12 m 30.159 20.497   3 11.834 0.6796 6.6, 43.906 -0.32
BXD27 m 15.803 11.615   4 5.8073 0.735 5.632, 32.43 -0.53
BXD32 m 140.1 101.2   5 45.239 0.7222 39.038, 271.5 1.25
BXD34 m 128.9 90.62   5 40.527 0.7028 13.406, 219.1 1.09
BXD39 m 26.679 31.741   3 18.326 1.1897 0.598, 62.02 -0.37
BXD40 m 147.2 94.01   4 47.007 0.6386 20.388, 247.1 1.35
BXD43 m 6.168 4.5655   7 1.7256 0.7402 0.78, 14.18 -0.66
BXD45 m 18.845 16.704   4 8.3521 0.8864 2.806, 39.922 -0.48
BXD48 m 18.181 5.9715   5 2.6705 0.3284 10.81, 25.868 -0.49
BXD48a m 32.718 22.374   4 11.187 0.6838 8.178, 53.62 -0.29
BXD49 m 119.6 107.3   5 47.985 0.897 7.442, 236.8 0.96
BXD51 m 4.018 2.3755   5 1.0624 0.5912 1.65, 7.912 -0.7
BXD53 m 40.318 74.93   4 37.466 1.8585 1.264, 152.7 -0.18
BXD55 m 61.98 30.104   5 13.463 0.4857 32.272, 112.1 0.13
BXD6 m 272.7 196.2   5 87.76 0.7196 51.35, 533.1 3.14
BXD62 m 4.8468 2.0025   5 0.89554 0.4132 3.292, 8.132 -0.68
BXD63 m 12.46 7.5185   4 3.7592 0.6034 5.67, 19.942 -0.58
BXD64 m 6.0608 4.3452   5 1.9432 0.7169 0.198, 10.918 -0.67
BXD66 m 3.5196 2.7075   5 1.2108 0.7693 1.296, 8.104 -0.7
BXD67 m 1.853 1.5606   4 0.7803 0.8422 0.388, 3.274 -0.73
BXD69 m 19.113 5.8481   5 2.6153 0.306 10.764, 25.52 -0.48
BXD73 m 97.91 124.6   4 62.29 1.2724 2.152, 267.6 0.65
BXD75 m 43.3 42.169   5 18.858 0.9739 7.212, 112.2 -0.13
BXD77 m 139.2 69.3   5 30.991 0.4978 34.96, 210.7 1.24
BXD79 m 5.6864 2.899   5 1.2965 0.5098 2.886, 9.316 -0.67
BXD8 m 2.4348 1.0424   5 0.46618 0.4281 0.688, 3.316 -0.72
BXD81 m 36.166 28.703   3 16.572 0.7937 9.26, 66.38 -0.24
BXD84 m 2.5271 2.0711   5 0.92623 0.8195 0.498, 5.304 -0.72
BXD87 m 258.9 240.1   5 107.4 0.9272 114.7, 686.0 2.95
BXD89 m 7.1357 5.9999   6 2.4495 0.8408 0.188, 17.134 -0.65
BXD90 m 12.214 23.233   5 10.39 1.9021 1.298, 53.77 -0.58
C57BL/6J m 121.2 110.5   5 49.437 0.9123 6.77, 298.3 0.98
DBA/2J m 19.692 30.15   4 15.075 1.5311 3.83, 64.9 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 23.0068 32.5983794292 87.4941705033 -41.4805705033
BXD100 m 6.092 32.5983794292 70.5793705033 -58.3953705033
BXD11 m 10.891 36.44609618 82.9900720677 -61.2080720677
BXD12 m 30.1586666667 42.0843268809 113.4115039999 -53.0941706666
BXD27 m 15.8025 36.44609618 87.9015720677 -56.2965720677
BXD32 m 140.0696 32.5983794292 204.5569705033 75.5822294967
BXD34 m 128.9472 32.5983794292 193.4345705033 64.4598294967
BXD39 m 26.6786666667 42.0843268809 109.9315039999 -56.5741706666
BXD40 m 147.222 36.44609618 219.3210720677 75.1229279323
BXD43 m 6.168 27.5506590718 60.6697755571 -48.3337755571
BXD45 m 18.8445 36.44609618 90.9435720677 -53.2545720677
BXD48 m 18.1812 32.5983794292 82.6685705033 -46.3061705033
BXD48a m 32.7175 36.44609618 104.8165720677 -39.3815720677
BXD49 m 119.6248 32.5983794292 184.1121705033 55.1374294967
BXD51 m 4.018 32.5983794292 68.5053705033 -60.4693705033
BXD53 m 40.3185 36.44609618 112.4175720677 -31.7805720677
BXD55 m 61.9764 32.5983794292 126.4637705033 -2.5109705033
BXD6 m 272.69 32.5983794292 337.1773705033 208.2026294967
BXD62 m 4.8468 32.5983794292 69.3341705033 -59.6405705033
BXD63 m 12.4595 36.44609618 84.5585720677 -59.6395720677
BXD64 m 6.0608 32.5983794292 70.5481705033 -58.4265705033
BXD66 m 3.5196 32.5983794292 68.0069705033 -60.9677705033
BXD67 m 1.853 36.44609618 73.9520720677 -70.2460720677
BXD69 m 19.1132 32.5983794292 83.6005705033 -45.3741705033
BXD73 m 97.9105 36.44609618 170.0095720677 25.8114279323
BXD75 m 43.2996 32.5983794292 107.7869705033 -21.1877705033
BXD77 m 139.212 32.5983794292 203.6993705033 74.7246294967
BXD79 m 5.6864 32.5983794292 70.1737705033 -58.8009705033
BXD8 m 2.4348 32.5983794292 66.9221705033 -62.0525705033
BXD81 m 36.166 42.0843268809 119.4188373333 -47.0868373333
BXD84 m 2.52714 32.5983794292 67.0145105033 -61.9602305033
BXD87 m 258.9 32.5983794292 323.3873705033 194.4126294967
BXD89 m 7.1356666667 29.7581129191 66.004312498 -51.7329791647
BXD90 m 12.214 32.5983794292 76.7013705033 -52.2733705033
C57BL/6J m 121.174 32.5983794292 185.6613705033 56.6866294967
DBA/2J m 19.692 36.44609618 91.7910720677 -52.4070720677




  GWAS USING LINEAR MIXED MODELS