Project measure / variable:   Schoonjans1   bMCA_plasma_t0_HFD

ID, description, units MPD:112653   bMCA_plasma_t0_HFD   plasma bile acid β-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid β-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means52.77   ng/mL
Median of the strain means39.438   ng/mL
SD of the strain means± 42.855
Coefficient of variation (CV)0.8121
Min–max range of strain means8.312   –   176.0   ng/mL
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 262931.0133 7512.3147 1.6682 0.0222
Residuals 120 540395.7412 4503.2978


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 15.146 9.8493   5 4.4048 0.6503 5.632, 27.532 -0.88
BXD100 m 14.733 10.697   9 3.5657 0.7261 3.696, 36.272 -0.89
BXD11 m 115.4 132.5   3 76.51 1.1487 26.85, 267.7 1.46
BXD12 m 101.5 114.5   3 66.12 1.1283 30.218, 233.6 1.14
BXD27 m 94.71 123.2   5 55.12 1.3012 5.694, 307.2 0.98
BXD32 m 52.48 23.252   4 11.626 0.443 25.422, 74.6 -0.01
BXD34 m 50.23 28.771   4 14.385 0.5727 33.706, 93.28 -0.06
BXD39 m 36.373 32.454   3 18.737 0.8922 9.036, 72.24 -0.38
BXD40 m 78.85 73.02   4 36.51 0.9261 31.534, 187.5 0.61
BXD43 m 19.897 11.738   5 5.2492 0.5899 3.176, 31.194 -0.77
BXD45 m 44.14 19.522   5 8.7305 0.4423 20.592, 66.54 -0.2
BXD48 m 11.976 5.7607   5 2.5763 0.481 8.362, 22.204 -0.95
BXD48a m 19.715 10.06   4 5.0302 0.5103 9.148, 31.328 -0.77
BXD49 m 104.9 132.4   5 59.19 1.2613 16.3, 335.1 1.22
BXD51 m 9.954 2.0852   3 1.2039 0.2095 8.116, 12.22 -1.0
BXD53 m 29.915 24.921   5 11.145 0.8331 6.136, 71.84 -0.53
BXD55 m 90.22 83.25   5 37.231 0.9227 19.07, 218.5 0.87
BXD6 m 176.0 171.7   5 76.77 0.9754 31.992, 375.4 2.88
BXD62 m 93.91 75.65   4 37.823 0.8055 50.22, 207.0 0.96
BXD63 m 42.502 39.111   5 17.491 0.9202 21.2, 112.3 -0.24
BXD64 m 28.105 26.853   5 12.009 0.9555 4.67, 68.79 -0.58
BXD66 m 19.935 9.2436   3 5.3368 0.4637 10.288, 28.714 -0.77
BXD67 m 53.83 26.942   5 12.049 0.5005 18.322, 85.75 0.02
BXD69 m 15.112 9.561   4 4.7805 0.6327 5.192, 27.488 -0.88
BXD73 m 112.4 115.6   3 66.73 1.0284 42.274, 245.8 1.39
BXD75 m 33.692 49.991   4 24.995 1.4838 4.934, 108.5 -0.45
BXD77 m 56.2 46.99   5 21.014 0.8362 21.072, 136.1 0.08
BXD79 m 60.11 33.021   5 14.768 0.5493 27.254, 115.6 0.17
BXD8 m 156.8 206.5   3 119.2 1.3168 27.182, 395.0 2.43
BXD81 m 28.868 11.944   5 5.3415 0.4137 9.732, 38.892 -0.56
BXD84 m 22.863 15.433   5 6.9019 0.675 8.348, 46.28 -0.7
BXD87 m 26.314 22.769   4 11.384 0.8653 3.722, 56.04 -0.62
BXD89 m 45.788 45.2   5 20.214 0.9872 8.42, 123.1 -0.16
BXD90 m 14.458 11.496   4 5.7479 0.7951 6.19, 31.25 -0.89
C57BL/6J m 8.312 8.2279   2   5.818 0.9899 2.494, 14.13 -1.04
DBA/2J m 14.523 8.7679   3 5.0621 0.6037 6.812, 24.06 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 15.146 30.0109907966 74.5656731649 -44.2736731649
BXD100 m 14.7326666667 22.3688718311 59.0214761325 -29.5561427991
BXD11 m 115.3533333333 38.7440225195 192.0638015349 38.6428651318
BXD12 m 101.4993333333 38.7440225195 178.2098015349 24.7888651318
BXD27 m 94.7104 30.0109907966 154.1300731649 35.2907268351
BXD32 m 52.4835 33.5533077467 118.9167141987 -13.9497141987
BXD34 m 50.233 33.5533077467 116.6662141987 -16.2002141987
BXD39 m 36.3733333333 38.7440225195 113.0838015349 -40.3371348682
BXD40 m 78.8505 33.5533077467 145.2837141987 12.4172858013
BXD43 m 19.8972 30.0109907966 79.3168731649 -39.5224731649
BXD45 m 44.1404 30.0109907966 103.5600731649 -15.2792731649
BXD48 m 11.9756 30.0109907966 71.3952731649 -47.4440731649
BXD48a m 19.715 33.5533077467 86.1482141987 -46.7182141987
BXD49 m 104.9372 30.0109907966 164.3568731649 45.5175268351
BXD51 m 9.954 38.7440225195 86.6644682015 -66.7564682015
BXD53 m 29.9152 30.0109907966 89.3348731649 -29.5044731649
BXD55 m 90.2232 30.0109907966 149.6428731649 30.8035268351
BXD6 m 176.0056 30.0109907966 235.4252731649 116.5859268351
BXD62 m 93.9075 33.5533077467 160.3407141987 27.4742858013
BXD63 m 42.502 30.0109907966 101.9216731649 -16.9176731649
BXD64 m 28.1052 30.0109907966 87.5248731649 -31.3144731649
BXD66 m 19.935 38.7440225195 96.6454682015 -56.7754682015
BXD67 m 53.8264 30.0109907966 113.2460731649 -5.5932731649
BXD69 m 15.1125 33.5533077467 81.5457141987 -51.3207141987
BXD73 m 112.3946666667 38.7440225195 189.1051348682 35.6841984651
BXD75 m 33.692 33.5533077467 100.1252141987 -32.7412141987
BXD77 m 56.1956 30.0109907966 115.6152731649 -3.2240731649
BXD79 m 60.114 30.0109907966 119.5336731649 0.6943268351
BXD8 m 156.842 38.7440225195 233.5524682015 80.1315317985
BXD81 m 28.868 30.0109907966 88.2876731649 -30.5516731649
BXD84 m 22.8632 30.0109907966 82.2828731649 -36.5564731649
BXD87 m 26.3135 33.5533077467 92.7467141987 -40.1197141987
BXD89 m 45.7876 30.0109907966 105.2072731649 -13.6320731649
BXD90 m 14.4585 33.5533077467 80.8917141987 -51.9747141987
C57BL/6J m 8.312 47.4515428778 102.2627525119 -85.6387525119
DBA/2J m 14.5226666667 38.7440225195 91.2331348682 -62.1878015349




  GWAS USING LINEAR MIXED MODELS