Project measure / variable:   Schoonjans1   aMCA_plasma_t0_HFD

ID, description, units MPD:112651   aMCA_plasma_t0_HFD   plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means9.9603   ng/mL
Median of the strain means8.0948   ng/mL
SD of the strain means± 7.9438
Coefficient of variation (CV)0.7975
Min–max range of strain means1.583   –   39.406   ng/mL
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 6286.5424 190.5013 0.9846 0.5032
Residuals 94 18187.174 193.4806


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.6165 0.59599   3 0.3441 0.3687 1.012, 2.2036 -1.05
BXD100 m 5.813 4.5302   4 2.2651 0.7793 1.84, 12.28 -0.52
BXD11 m 4.3087 2.3862   3 1.3777 0.5538 2.926, 7.064 -0.71
BXD12 m 39.406 59.66   3 34.447 1.5141 4.848, 108.3 3.71
BXD27 m 25.725 39.141   4 19.571 1.5216 2.352, 84.28 1.98
BXD32 m 4.637 1.792   4 0.89601 0.3865 2.248, 6.446 -0.67
BXD34 m 8.281 6.8332   4 3.4166 0.8252 3.278, 18.032 -0.21
BXD39 m 14.188 0.56286   2   0.398 0.0397 13.79, 14.586 0.53
BXD40 m 10.207 8.4196   3 4.861 0.8249 3.228, 19.558 0.03
BXD43 m 1.68 0.0   1   0.0 0.0 1.68, 1.68 -1.04
BXD45 m 7.6444 2.048   5 0.91589 0.2679 4.598, 9.718 -0.29
BXD48 m 5.132 2.7391   5 1.225 0.5337 3.518, 9.952 -0.61
BXD48a m 8.098 3.2719   4 1.6359 0.404 4.06, 11.936 -0.23
BXD49 m 12.457 12.576   4 6.2881 1.0095 4.526, 31.096 0.31
BXD51 m 1.583 0.69155   2   0.489 0.4369 1.094, 2.072 -1.05
BXD53 m 9.2278 3.7117   5 1.6599 0.4022 2.686, 11.554 -0.09
BXD55 m 16.441 14.924   5 6.6741 0.9077 2.422, 38.964 0.82
BXD6 m 17.52 17.418   4 8.7091 0.9942 2.84, 39.622 0.95
BXD62 m 11.979 14.478   4 7.2388 1.2086 3.588, 33.654 0.25
BXD63 m 7.6464 8.4347   5 3.7721 1.1031 2.272, 22.426 -0.29
BXD64 m 8.55 7.235   4 3.6175 0.8462 2.894, 19.0 -0.18
BXD66 m 6.5935 2.0947   3 1.2094 0.3177 4.524, 8.7125 -0.42
BXD67 m 11.423 7.2611   5 3.2473 0.6356 3.438, 22.164 0.18
BXD69 m 10.183 8.1049   2   5.731 0.7959 4.452, 15.914 0.03
BXD73 m 15.153 16.157   3 9.3283 1.0663 4.274, 33.718 0.65
BXD75 m 4.451 4.8311   4 2.4155 1.0854 1.182, 11.608 -0.69
BXD77 m 19.31 17.022   5 7.6127 0.8815 4.478, 46.794 1.18
BXD79 m 3.9152 2.3377   5 1.0455 0.5971 1.84, 7.91 -0.76
BXD8 m 26.202 0.0   1   0.0 0.0 26.202, 26.202 2.04
BXD81 m 9.2256 5.458   5 2.4409 0.5916 3.678, 15.292 -0.09
BXD84 m 6.008 5.4655   4 2.7328 0.9097 2.034, 13.774 -0.5
BXD87 m 1.868 0.66549   3 0.38422 0.3563 1.432, 2.634 -1.02
BXD89 m 8.0916 7.0193   5 3.1391 0.8675 2.062, 19.958 -0.24
BXD90 m 6.756 8.7296   3 5.04 1.2921 1.176, 16.816 -0.4
C57BL/6J m 4.786 2.8115   2   1.988 0.5874 2.798, 6.774 -0.65
DBA/2J m 2.463 0.24466   2   0.173 0.0993 2.29, 2.636 -0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.6165333333 8.0307860759 17.5618473437 -14.3287806771
BXD100 m 5.813 6.9548647541 19.6220470043 -7.9960470043
BXD11 m 4.3086666667 8.0307860759 20.2539806771 -11.6366473437
BXD12 m 39.406 8.0307860759 55.3513140104 23.4606859896
BXD27 m 25.7245 6.9548647541 39.5335470043 11.9154529957
BXD32 m 4.637 6.9548647541 18.4460470043 -9.1720470043
BXD34 m 8.281 6.9548647541 22.0900470043 -5.5280470043
BXD39 m 14.188 9.8356640597 33.7169415569 -5.3409415569
BXD40 m 10.2066666667 8.0307860759 26.1519806771 -5.7386473437
BXD45 m 7.6444 6.2206201458 19.9955871225 -4.7067871225
BXD48 m 5.132 6.2206201458 17.4831871225 -7.2191871225
BXD48a m 8.098 6.9548647541 21.9070470043 -5.7110470043
BXD49 m 12.4575 6.9548647541 26.2665470043 -1.3515470043
BXD51 m 1.583 9.8356640597 21.1119415569 -17.9459415569
BXD53 m 9.2278 6.2206201458 21.5789871225 -3.1233871225
BXD55 m 16.4412 6.2206201458 28.7923871225 4.0900128775
BXD6 m 17.520075 6.9548647541 31.3291220043 3.7110279957
BXD62 m 11.979 6.9548647541 25.7880470043 -1.8300470043
BXD63 m 7.6464 6.2206201458 19.9975871225 -4.7047871225
BXD64 m 8.55 6.9548647541 22.3590470043 -5.2590470043
BXD66 m 6.5935 8.0307860759 22.5388140104 -9.3518140104
BXD67 m 11.4232 6.2206201458 23.7743871225 -0.9279871225
BXD69 m 10.183 9.8356640597 29.7119415569 -9.3459415569
BXD73 m 15.1526666667 8.0307860759 31.0979806771 -0.7926473437
BXD75 m 4.451 6.9548647541 18.2600470043 -9.3580470043
BXD77 m 19.31 6.2206201458 31.6611871225 6.9588128775
BXD79 m 3.9152 6.2206201458 16.2663871225 -8.4359871225
BXD81 m 9.2256 6.2206201458 21.5767871225 -3.1255871225
BXD84 m 6.008 6.9548647541 19.8170470043 -7.8010470043
BXD87 m 1.868 8.0307860759 17.8133140104 -14.0773140104
BXD89 m 8.0916 6.2206201458 20.4427871225 -4.2595871225
BXD90 m 6.756 8.0307860759 22.7013140104 -9.1893140104
C57BL/6J m 4.786 9.8356640597 24.3149415569 -14.7429415569
DBA/2J m 2.463 9.8356640597 21.9919415569 -17.0659415569




  GWAS USING LINEAR MIXED MODELS