Project measure / variable:   Schoonjans1   keto_DCA_plasma_t0_HFD

ID, description, units MPD:112649   keto_DCA_plasma_t0_HFD   plasma bile acid 7-ketodeoxycholic acid, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   35 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 7-ketodeoxycholic acid, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means2.0081   ng/mL
Median of the strain means1.2008   ng/mL
SD of the strain means± 2.3705
Coefficient of variation (CV)1.1805
Min–max range of strain means0.259   –   12.513   ng/mL
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 848.4792 25.7115 1.1908 0.2567
Residuals 88 1900.1221 21.5923


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.30068 0.1088   4 0.0544 0.3618 0.22, 0.46071 -0.72
BXD100 m 0.95467 0.15074   3 0.08703 0.1579 0.782, 1.06 -0.44
BXD11 m 0.76733 0.59231   3 0.34197 0.7719 0.226, 1.4 -0.52
BXD12 m 1.1093 1.3262   3 0.76569 1.1955 0.242, 2.636 -0.38
BXD27 m 3.9933 4.9315   3 2.8472 1.2349 0.708, 9.664 0.84
BXD32 m 0.91467 0.53181   3 0.30704 0.5814 0.336, 1.382 -0.46
BXD34 m 1.376 1.6655   4 0.83277 1.2104 0.51, 3.874 -0.27
BXD39 m 4.023 2.7195   2   1.923 0.676 2.1, 5.946 0.85
BXD40 m 1.538 1.5637   4 0.78183 1.0167 0.396, 3.714 -0.2
BXD43 m 0.394 0.0   1   0.0 0.0 0.394, 0.394 -0.68
BXD45 m 1.6356 1.1544   5 0.51624 0.7058 0.252, 2.836 -0.16
BXD48 m 0.70267 0.582   3 0.33602 0.8283 0.288, 1.368 -0.55
BXD48a m 1.7515 1.0212   4 0.51058 0.583 0.89, 2.956 -0.11
BXD49 m 12.513 17.803   5 7.9616 1.4228 0.624, 43.342 4.43
BXD53 m 1.7644 1.28   5 0.57244 0.7255 0.41, 3.89 -0.1
BXD55 m 5.9824 6.4659   5 2.8916 1.0808 0.392, 13.478 1.68
BXD6 m 5.5352 6.2755   5 2.8065 1.1338 0.83235, 15.311 1.49
BXD62 m 0.5905 0.64675   4 0.32338 1.0953 0.212, 1.554 -0.6
BXD63 m 0.7544 0.75874   5 0.33932 1.0058 0.3, 2.064 -0.53
BXD64 m 0.929 0.98327   4 0.49163 1.0584 0.254, 2.386 -0.46
BXD66 m 0.47354 0.21448   3 0.12383 0.4529 0.226, 0.604 -0.65
BXD67 m 1.2056 0.68056   5 0.30435 0.5645 0.248, 2.154 -0.34
BXD69 m 2.3367 2.6301   3 1.5185 1.1256 0.266, 5.296 0.14
BXD73 m 1.8707 2.264   3 1.3071 1.2103 0.458, 4.482 -0.06
BXD75 m 2.2005 3.4278   4 1.7139 1.5577 0.22, 7.328 0.08
BXD77 m 1.2008 1.3717   5 0.61345 1.1423 0.26, 3.56 -0.34
BXD79 m 0.444 0.19799   2   0.14 0.4459 0.304, 0.584 -0.66
BXD8 m 3.632 4.4208   2   3.126 1.2172 0.506, 6.758 0.69
BXD81 m 1.2495 0.21924   4 0.10962 0.1755 0.944, 1.466 -0.32
BXD84 m 0.422 0.12402   4 0.06201 0.2939 0.258, 0.522 -0.67
BXD87 m 0.701 0.5671   2   0.401 0.809 0.3, 1.102 -0.55
BXD89 m 4.8384 5.4321   5 2.4293 1.1227 0.378, 13.214 1.19
BXD90 m 0.97 1.0607   2   0.75 1.0935 0.22, 1.72 -0.44
C57BL/6J m 0.95 0.93055   2   0.658 0.9795 0.292, 1.608 -0.45
DBA/2J m 0.259 0.00141421   2   0.001 0.0055 0.258, 0.26 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.3006775 2.3233756207 4.9178983232 -4.3165433232
BXD100 m 0.9546666667 2.6828030801 6.286174037 -4.3768407037
BXD11 m 0.7673333333 2.6828030801 6.0988407037 -4.564174037
BXD12 m 1.1093333333 2.6828030801 6.4408407037 -4.222174037
BXD27 m 3.9933333333 2.6828030801 9.3248407037 -1.338174037
BXD32 m 0.9146666667 2.6828030801 6.246174037 -4.4168407037
BXD34 m 1.376 2.3233756207 5.9932208232 -3.2412208232
BXD39 m 4.023 3.2857493133 10.5527363086 -2.5067363086
BXD40 m 1.538 2.3233756207 6.1552208232 -3.0792208232
BXD45 m 1.6356 2.07809033 5.7653678511 -2.4941678511
BXD48 m 0.7026666667 2.6828030801 6.034174037 -4.6288407037
BXD48a m 1.7515 2.3233756207 6.3687208232 -2.8657208232
BXD49 m 12.5128 2.07809033 16.6425678511 8.3830321489
BXD53 m 1.7644 2.07809033 5.8941678511 -2.3653678511
BXD55 m 5.9824 2.07809033 10.1121678511 1.8526321489
BXD6 m 5.53517 2.07809033 9.6649378511 1.4054021489
BXD62 m 0.5905 2.3233756207 5.2077208232 -4.0267208232
BXD63 m 0.7544 2.07809033 4.8841678511 -3.3753678511
BXD64 m 0.929 2.3233756207 5.5462208232 -3.6882208232
BXD66 m 0.47354 2.6828030801 5.8050473703 -4.8579673703
BXD67 m 1.2056 2.07809033 5.3353678511 -2.9241678511
BXD69 m 2.3366666667 2.6828030801 7.668174037 -2.9948407037
BXD73 m 1.8706666667 2.6828030801 7.202174037 -3.4608407037
BXD75 m 2.2005 2.3233756207 6.8177208232 -2.4167208232
BXD77 m 1.2008 2.07809033 5.3305678511 -2.9289678511
BXD79 m 0.444 3.2857493133 6.9737363086 -6.0857363086
BXD8 m 3.632 3.2857493133 10.1617363086 -2.8977363086
BXD81 m 1.2495 2.3233756207 5.8667208232 -3.3677208232
BXD84 m 0.422 2.3233756207 5.0392208232 -4.1952208232
BXD87 m 0.701 3.2857493133 7.2307363086 -5.8287363086
BXD89 m 4.8384 2.07809033 8.9681678511 0.7086321489
BXD90 m 0.97 3.2857493133 7.4997363086 -5.5597363086
C57BL/6J m 0.95 3.2857493133 7.4797363086 -5.5797363086
DBA/2J m 0.259 3.2857493133 6.7887363086 -6.2707363086




  GWAS USING LINEAR MIXED MODELS