Project measure / variable:   Schoonjans1   keto_DCA_plasma_t0_CD

ID, description, units MPD:112648   keto_DCA_plasma_t0_CD   plasma bile acid 7-ketodeoxycholic acid, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   35 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 7-ketodeoxycholic acid, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means10.241   ng/mL
Median of the strain means3.732   ng/mL
SD of the strain means± 20.997
Coefficient of variation (CV)2.0503
Min–max range of strain means0.3152   –   116.2   ng/mL
Mean sample size per strain4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 72944.9025 2210.4516 2.5339 0.0002
Residuals 107 93343.2914 872.3672


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 13.214 22.318   3 12.885 1.6889 0.322, 38.985 0.14
BXD100 m 0.676 0.39917   4 0.19958 0.5905 0.346, 1.256 -0.46
BXD11 m 1.483 0.63553   4 0.31776 0.4285 0.726, 2.246 -0.42
BXD12 m 10.857 16.678   3 9.6288 1.5361 0.578, 30.1 0.03
BXD27 m 2.035 2.2207   4 1.1104 1.0913 0.65, 5.346 -0.39
BXD32 m 7.044 4.773   5 2.1345 0.6776 2.6, 14.508 -0.15
BXD34 m 8.0008 6.4523   5 2.8855 0.8065 0.752, 15.84 -0.11
BXD39 m 3.217 3.9697   2   2.807 1.234 0.41, 6.024 -0.33
BXD40 m 11.018 7.014   4 3.507 0.6366 1.236, 17.64 0.04
BXD43 m 0.388 0.21299   6 0.08695 0.549 0.224, 0.714 -0.47
BXD45 m 7.032 6.4917   4 3.2458 0.9232 0.89, 15.328 -0.15
BXD48 m 2.3904 0.94725   5 0.42362 0.3963 1.206, 3.262 -0.37
BXD48a m 4.6255 2.7139   4 1.357 0.5867 1.41, 7.334 -0.27
BXD49 m 116.2 138.8   5 62.09 1.1947 3.16, 290.7 5.05
BXD53 m 9.8645 17.407   4 8.7035 1.7646 0.514, 35.962 -0.02
BXD55 m 30.422 25.335   5 11.33 0.8328 15.084, 75.38 0.96
BXD6 m 49.018 37.36   5 16.708 0.7622 7.506, 93.69 1.85
BXD62 m 0.656 0.34549   4 0.17275 0.5267 0.25, 1.006 -0.46
BXD63 m 1.0405 0.69816   4 0.34908 0.671 0.398, 1.896 -0.44
BXD64 m 0.5355 0.20281   4 0.1014 0.3787 0.246, 0.704 -0.46
BXD66 m 0.525 0.02687   2   0.019 0.0512 0.506, 0.544 -0.46
BXD67 m 0.63533 0.27331   3 0.15779 0.4302 0.32, 0.804 -0.46
BXD69 m 1.7628 0.75622   5 0.33819 0.429 1.248, 3.096 -0.4
BXD73 m 11.377 13.599   4 6.7993 1.1953 0.278, 28.82 0.05
BXD75 m 4.2787 2.4563   5 1.0985 0.5741 2.208, 8.0385 -0.28
BXD77 m 5.5876 5.0001   5 2.2361 0.8948 1.846, 14.174 -0.22
BXD79 m 0.6424 0.18032   5 0.08064 0.2807 0.392, 0.854 -0.46
BXD8 m 0.3152 0.06945   5 0.03106 0.2203 0.208, 0.394 -0.47
BXD81 m 5.4222 1.7364   2   1.2278 0.3202 4.1944, 6.65 -0.23
BXD84 m 0.45867 0.16523   3 0.0954 0.3602 0.268, 0.56 -0.47
BXD87 m 23.824 28.09   5 12.562 1.1791 9.346, 74.03 0.65
BXD89 m 1.2135 0.95789   4 0.47894 0.7894 0.258, 2.506 -0.43
BXD90 m 3.732 0.0   1   0.0 0.0 3.732, 3.732 -0.31
C57BL/6J m 17.643 17.295   5 7.7343 0.9802 0.912, 40.43 0.35
DBA/2J m 1.2985 1.5917   4 0.79587 1.2258 0.212, 3.636 -0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 13.2143333333 17.0525385177 47.01900211 -20.5903354434
BXD100 m 0.676 14.7679315553 29.9517019271 -28.5997019271
BXD11 m 1.483 14.7679315553 30.7587019271 -27.7927019271
BXD12 m 10.8573333333 17.0525385177 44.66200211 -22.9473354434
BXD27 m 2.035 14.7679315553 31.3107019271 -27.2407019271
BXD32 m 7.044 13.2088395379 33.2289838392 -19.1409838392
BXD34 m 8.0008 13.2088395379 34.1857838392 -18.1841838392
BXD39 m 3.217 20.8850090937 44.6190947133 -38.1850947133
BXD40 m 11.0185 14.7679315553 40.2942019271 -18.2572019271
BXD43 m 0.388 12.0579656223 24.2915105278 -23.5155105278
BXD45 m 7.032 14.7679315553 36.3077019271 -22.2437019271
BXD48 m 2.3904 13.2088395379 28.5753838392 -23.7945838392
BXD48a m 4.6255 14.7679315553 33.9012019271 -24.6502019271
BXD49 m 116.2016 13.2088395379 142.3865838392 90.0166161608
BXD53 m 9.8645 14.7679315553 39.1402019271 -19.4112019271
BXD55 m 30.422 13.2088395379 56.6069838392 4.2370161608
BXD6 m 49.0176 13.2088395379 75.2025838392 22.8326161608
BXD62 m 0.656 14.7679315553 29.9317019271 -28.6197019271
BXD63 m 1.0405 14.7679315553 30.3162019271 -28.2352019271
BXD64 m 0.5355 14.7679315553 29.8112019271 -28.7402019271
BXD66 m 0.525 20.8850090937 41.9270947133 -40.8770947133
BXD67 m 0.6353333333 17.0525385177 34.44000211 -33.1693354434
BXD69 m 1.7628 13.2088395379 27.9477838392 -24.4221838392
BXD73 m 11.377 14.7679315553 40.6527019271 -17.8987019271
BXD75 m 4.27874 13.2088395379 30.4637238392 -21.9062438392
BXD77 m 5.5876 13.2088395379 31.7725838392 -20.5973838392
BXD79 m 0.6424 13.2088395379 26.8273838392 -25.5425838392
BXD8 m 0.3152 13.2088395379 26.5001838392 -25.8697838392
BXD81 m 5.4222 20.8850090937 46.8242947133 -35.9798947133
BXD84 m 0.4586666667 17.0525385177 34.2633354434 -33.34600211
BXD87 m 23.8236 13.2088395379 50.0085838392 -2.3613838392
BXD89 m 1.2135 14.7679315553 30.4892019271 -28.0622019271
C57BL/6J m 17.6432 13.2088395379 43.8281838392 -8.5417838392
DBA/2J m 1.2985 14.7679315553 30.5742019271 -27.9772019271




  GWAS USING LINEAR MIXED MODELS