Project measure / variable:   Schoonjans1   oxo_CA_plasma_t0_HFD

ID, description, units MPD:112647   oxo_CA_plasma_t0_HFD   plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   15 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means5.0728   ng/mL
Median of the strain means4.49   ng/mL
SD of the strain means± 2.2958
Coefficient of variation (CV)0.4526
Min–max range of strain means2.722   –   10.196   ng/mL
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 3 20.5665 6.8555 1.7618 0.293
Residuals 4 15.5644 3.8911


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD27 m 10.196 0.0   1   0.0 0.0 10.196, 10.196 2.23
BXD34 m 2.968 0.0   1   0.0 0.0 2.968, 2.968 -0.92
BXD39 m 5.334 0.0   1   0.0 0.0 5.334, 5.334 0.11
BXD40 m 2.936 0.0   1   0.0 0.0 2.936, 2.936 -0.93
BXD49 m 6.712 3.8212   2   2.702 0.5693 4.01, 9.414 0.71
BXD55 m 6.692 0.12162   2   0.086 0.0182 6.606, 6.778 0.71
BXD6 m 8.4833 0.0   1   0.0 0.0 8.4833, 8.4833 1.49
BXD63 m 4.49 0.0   1   0.0 0.0 4.49, 4.49 -0.25
BXD64 m 3.377 0.88106   2   0.623 0.2609 2.754, 4.0 -0.74
BXD69 m 2.794 0.0   1   0.0 0.0 2.794, 2.794 -0.99
BXD73 m 3.692 0.0   1   0.0 0.0 3.692, 3.692 -0.6
BXD75 m 6.968 0.0   1   0.0 0.0 6.968, 6.968 0.83
BXD77 m 2.722 0.0   1   0.0 0.0 2.722, 2.722 -1.02
BXD8 m 5.104 0.0   1   0.0 0.0 5.104, 5.104 0.01
BXD89 m 3.623 0.41436   2   0.293 0.1144 3.33, 3.916 -0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD49 m 6.712 1.3948277671 10.5846627267 2.8393372733
BXD55 m 6.692 1.3948277671 10.5646627267 2.8193372733
BXD64 m 3.377 1.3948277671 7.2496627267 -0.4956627267
BXD89 m 3.623 1.3948277671 7.4956627267 -0.2496627267




  GWAS USING LINEAR MIXED MODELS